Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Stephen Gilheeney"'
Autor:
Sameer Farouk Sait, Mauricio Rendon Bernot, Elizabeth Klein, David H. Abramson, Jasmine H. Francis, Stephen Gilheeney, Matthias A. Karajannis, Barbara Spitzer, Suzanne Wolden, Ira J. Dunkel, Nancy A. Kernan
Publikováno v:
Pediatric Blood & Cancer. 70
Stage 4a metastatic retinoblastoma (RB) is curable with intensive multimodality therapy including myeloablative chemotherapy with autologous stem cell transplant (HDC-ASCT) and involved field radiation therapy (IFRT). To our knowledge, no data exist
Autor:
Cassie Martinez, Stephen Gilheeney, Andrew L. Kung, Victoria Szenes, James Killinger, Mini Kamboj, Deborah Diotallevi, Giselle Melendez, Farid Boulad, Julia Glade Bender, Rachel Bright, Nicole Zakak, Stephen S. Roberts
Publikováno v:
J Pediatr Oncol Nurs
Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) first reached the United States in January 2020. Located in New York City (NYC), MSK Kids, at Memorial Sloan Kettering Cancer Center services, is one of the largest pediatric ca
Autor:
Michael Karremann, Olaf Witt, Tabitha Bloom, Winand N.M. Dinjens, Felipe Andreiuolo, Michael Farrell, Scott Newman, Simone Hettmer, James Dalton, Leslie R. Bridges, Jens Schittenhelm, Martin Ebinger, Thomas S. Jacques, Francesca Diomedi-Camassei, Dominik Sturm, Jane Chalker, Matija Snuderl, David W. Ellison, Paula Proszek, Irene Slavc, Matthias A. Karajannis, Giovanna Stefania Colafati, Louise Howell, Christine Haberler, Simon Bailey, Barbara C. Worst, David A. Solomon, Andrew J. Martin, Stefan M. Pfister, Maria Vinci, Ho Keung Ng, Kelly Haupfear, Mellissa Maybury, Stephen Gilheeney, Bassel Zebian, Martin Sill, David T.W. Jones, Pablo Hernáiz Driever, Martin U. Schuhmann, Angela Mastronuzzi, Jessica K.R. Boult, Matthew Clarke, Rachael Natrajan, Kornelius Kerl, Lawrence Doey, Alex Virasami, Andrey Korshunov, Christof M. Kramm, Jane Cryan, David E. Kram, Timothy E.G. Hassall, Debbie Hughes, Claire Mitchell, Chris Jones, Monika A. Davare, Evelina Miele, Safa Al-Sarraj, Sara Temelso, Catherine Rowe, Suzanne J. Baker, Sergey Popov, Torsten Pietsch, Matthew D. Wood, Roger J. Packer, Lynley V. Marshall, Michael Capra, Valeria Molinari, Diana Carvalho, Marc Zuckermann, Andreas von Deimling, Uwe Kordes, Kathreena M Kurian, Shani Caspi, Ira J. Dunkel, Wilda Orisme, Ulrich Schüller, Claire Cairns, Matthias Preusser, Kristian Aquilina, Petter Brandal, Stephen Lowis, Iris Stoler, Christopher Chandler, Lissa C. Baird, Marc K. Rosenblum, Ji Wen, Felix Sahm, Barbara Faganel Kotnik, Stephen Crosier, Mara Popović, Andrea Carai, Lotte Hiddingh, Thale Kristin Olsen, Fernando Carceller, Simon P. Robinson, Maria Tsoli, Ruth G. Tatevossian, Anna Burford, Mike Hubank, Elisa Izquierdo, Tejus Bale, David Capper, Andrew S. Moore, David S. Ziegler, Amy R Fairchild, Aimee Avery, Alan Mackay, Jessica C Pickles, Mark Kristiansen, Jeffrey Knipstein, Darren Hargrave, Mark J. Cowley, Tobey J. MacDonald, Britta Ismer
Publikováno v:
Cancer Discovery, 10(7), 942-963. American Association for Cancer Research Inc.
Clarke, M, Mackay, A, Ismer, B, Pickles, J C, Tatevossian, R G, Newman, S, Bale, T A, Stoler, I, Izquierdo, E, Temelso, S, Carvalho, D M, Molinari, V, Burford, A, Howell, L, Virasami, A, Fairchild, A R, Avery, A, Chalker, J, Kristiansen, M, Haupfear, K, Dalton, J D, Orisme, W, Wen, J, Hubank, M, Kurian, K M, Rowe, C & Lowis, S P 2020, ' Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes ', Cancer Discovery . https://doi.org/10.1158/2159-8290.CD-19-1030
Cancer Discov
Clarke, M, Mackay, A, Ismer, B, Pickles, J C, Tatevossian, R G, Newman, S, Bale, T A, Stoler, I, Izquierdo, E, Temelso, S, Carvalho, D M, Molinari, V, Burford, A, Howell, L, Virasami, A, Fairchild, A R, Avery, A, Chalker, J, Kristiansen, M, Haupfear, K, Dalton, J D, Orisme, W, Wen, J, Hubank, M, Kurian, K M, Rowe, C & Lowis, S P 2020, ' Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes ', Cancer Discovery . https://doi.org/10.1158/2159-8290.CD-19-1030
Cancer Discov
Infant high-grade gliomas appear clinically distinct from their counterparts in older children, indicating that histopathologic grading may not accurately reflect the biology of these tumors. We have collected 241 cases under 4 years of age, and carr
Autor:
Yasmin Khakoo, Maria I. Carlo, Elise Fiala, Ozge Ceyhan-Birsoy, Leonard H. Wexler, Nancy Bouvier, Diana Mandelker, Jasmine H. Francis, Alicia Latham, Sowmya Jairam, Marc Ladanyi, Gowtham Jayakumaran, Sameer Farouk Sait, Filemon S. Dela Cruz, Ira J. Dunkel, Michael Walsh, Michael F. Berger, Todd E. Heaton, Ellen M. Basu, Matthias A. Karajannis, Ciyu Yang, Christopher J. Forlenza, Neerav Shukla, Emily K. Slotkin, Julia Glade Bender, Tanya M. Trippett, Nai-Kong Cheung, Danielle Novetsky Friedman, Justin T. Gerstle, Semanti Murkherjee, Ahmet Zehir, Zsofia K. Stadler, Erin E. Salo-Mullen, Maria Luisa Sulis, Yelena Kemel, Karen Cadoo, Sabine Topka, Jennifer Kennedy, Megan Harlan Fleischut, Nikolaus Schultz, Richard J. O'Reilly, Anna Maio, Margaret Sheehan, Shakeel Modak, Michael V. Ortiz, Alex Kentsis, Andrew L. Kung, Paul A. Meyers, Stephen S. Roberts, Kenneth Offit, Angela G. Arnold, Mark E. Robson, David H. Abramson, Stephen Gilheeney, Liying Zhang, Audrey Mauguen, Joseph Vijai
Publikováno v:
Nat Cancer
Nature cancer, vol 2, iss 3
Nature cancer, vol 2, iss 3
The spectrum of germline predisposition in pediatric cancer continues to be realized. Here we report 751 solid tumor patients who underwent prospective matched tumor-normal DNA sequencing and downstream clinical use (clinicaltrials.gov NCT01775072).
Autor:
Pat Zanzonico, John L. Humm, Nai-Kong V. Cheung, Stephen Gilheeney, Kayleen Bailey, Kim Kramer, Neeta Pandit-Taskar
Publikováno v:
J Neurooncol
PURPOSE: We explored the use of intraventricular (131)I-8H9 targeting B7-H3 in patients with ETMR. METHODS: Patients were enrolled in an IRB approved, phase 1, 3+3 dose escalation trial. Patients with CNS disease expressing the antibody target antige
Autor:
Mrinal Joshirao, Sameer Farouk Sait, Nancy Bouvier, Katherine Hill, Yasmin Khakoo, Kim Kramer, Stephen Gilheeney, Suzanne Wolden, Craig Nolan, Lauren Schaff, Marc Rosenblum, Tejus A Bale, Jonathan T Yang, Andrew Lin, Ira J Dunkel, Matthias Karajannis
Publikováno v:
Neuro-Oncology. 24:i68-i68
INTRODUCTION: Patients receiving cranial radiotherapy (RT) are at risk for a subsequent radiation-induced glioma (RIG). RIGs are rare, generally develop with a latency of 2 years to several decades, display high-grade histology and an aggressive clin
Autor:
Katherine Hill, Alexandra M Miller, Bryan Kincheon Li, Nancy Bouvier, Shanita Li, Tina Alano, Seyram Doe-Tetteh, Claudia Huereca, Sara DiNapoli, Alex Lee, Luca Szalontay, Cecile Riviere-Cazaux, Terry C Burns, Sofia Haque, Tejus Bale, Jamal Benhamida, Snjezana Dogan, Chad Vanderbilt, Dara Ross, Jason Chang, Maria Donzelli, Ira J Dunkel, Sameer Farouk Sait, Yasmin Khakoo, Stephen Gilheeney, Mark Souweidane, Jeffrey Greenfield, Michael Berger, Ryma Benayed, Maria E Arcila, Marc Ladanyi, Ingo Mellinghoff, Matthias Karajannis
Publikováno v:
Neuro-Oncology. 24:i162-i162
PURPOSE: A subset of pediatric, adolescent and young adult (AYA) gliomas are located in the brainstem, eloquent locations, or present with diffuse/leptomeningeal disease, and are associated with high risk and low yield of biopsy. At the same time, ac
Autor:
Katarzyna Ibanez, Sofia Haque, Marc K. Rosenblum, Daniel E. Prince, Matthias A. Karajannis, Tejus Bale, Stephen Gilheeney, Ira J. Dunkel, Krisoula Spatz, Sameer Farouk Sait
Publikováno v:
Neuro Oncol
BACKGROUND Oncogenic driver alterations in fibroblast growth factor receptors (FGFRs) are present in a subset of pediatric gliomas. Debio1347 is an orally available, highly selective FGFR 1–3 inhibitor with a favorable safety profile and encouragin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f52be73e1eff0c9daae23755d3e1cc
https://europepmc.org/articles/PMC7651617/
https://europepmc.org/articles/PMC7651617/
Autor:
Stephen Gilheeney, Marc Dinkin, Krisoula Spatz, Matthias A. Karajannis, Sameer Farouk Sait, Ira J. Dunkel, Katarzyna Ibanez, Sofia Haque, Tejus Bale, Daniel E. Prince, Stephanie Vitolano, Marc K. Rosenblum
Publikováno v:
JCO Precis Oncol
Autor:
Cynthia Hawkins, Marilyn M. Li, Ana Guerreiro Stucklin, Matthias A. Karajannis, Annie Huang, Christopher Li, Lili-Naz Hazrati, Sanja Pajovic, Abhaya V. Kulkarni, Javal Sheth, James T. Rutka, Ibrahim Qaddoumi, Angela J. Waanders, Michael D. Taylor, Derek S. Tsang, Ruth G. Tatevossian, Robert Siddaway, James M. Drake, Uri Tabori, Anthony Arnoldo, Mary Shago, Ute Bartels, Colleen D’Arcy, David W. Ellison, Vijay Ramaswamy, Stephen Gilheeney, Manohar Shroff, Scott Ryall, Peter B. Dirks, Michal Zapotocky, Eric Bouffet, Lea F. Surrey, Alvaro Lassaletta, Tejus Bale, Liana Nobre, Monique Johnson, Marc K. Rosenblum, Julie Bennett, George M. Ibrahim, Mariarita Santi, Normand Laperriere, Suzanne Laughlin, Kohei Fukuoka, Wilda Orisme, Paul E. Kowalski
Publikováno v:
Cancer Cell
Pediatric low-grade gliomas (pLGG) are frequently driven by genetic alterations in the RAS-mitogen-activated protein kinase (RAS/MAPK) pathway yet show unexplained variability in their clinical outcome. To address this, we characterized a cohort of >