Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stephen Gadomski"'
Autor:
Claire Fielding, Andrés García-García, Claudia Korn, Stephen Gadomski, Zijian Fang, Juan L. Reguera, José A. Pérez-Simón, Berthold Göttgens, Simón Méndez-Ferrer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The sympathetic nervous system has been shown to respond to stress and activate haematopoietic stem cells. Here they show that cholinergic signals in the bone marrow preserve haematopoietic stem cell quiescence and self-renewal under proliferative st
Externí odkaz:
https://doaj.org/article/a37b394503a547f08085bab8d2e09c03
Autor:
Shweta Singh, Tanmoy Sarkar, Brad Jakubison, Stephen Gadomski, Andrew Spradlin, Kristbjorn O. Gudmundsson, Jonathan R. Keller
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adult mammalian hematopoiesis is a dynamic cellular process that provides a continuous supply of myeloid, lymphoid, erythroid/megakaryocyte cells for host survival. This process is sustained by regulating hematopoietic stem cells (HSCs) quiescence, p
Externí odkaz:
https://doaj.org/article/6c698dcc8e404e2284a5a3cc0e3e0ba5
Autor:
Stephen Gadomski, Satyendra K. Singh, Shweta Singh, Tanmoy Sarkar, Kimberly D. Klarmann, Maximillian Berenschot, Steven Seaman, Brad Jakubison, Kristbjorn O. Gudmundsson, Stephen Lockett, Jonathan R. Keller
Publikováno v:
Cell Reports, Vol 31, Iss 4, Pp - (2020)
Summary: Investigating mechanisms that regulate endothelial cell (EC) growth and survival is important for understanding EC homeostasis and how ECs maintain stem cell niches. We report here that targeted loss of Id genes in adult ECs results in dilat
Externí odkaz:
https://doaj.org/article/5e00d82cb9f044aeacd238721b815f03
Autor:
Stephen Gadomski, Claire Fielding, Andrés García-García, Claudia Korn, Chrysa Kapeni, Sadaf Ashraf, Javier Villadiego, Raquel del Toro, Olivia Domingues, Jeremy N. Skepper, Tatiana Michel, Jacques Zimmer, Regine Sendtner, Scott Dillon, Kenneth E.S. Poole, Gill Holdsworth, Michael Sendtner, Juan J. Toledo-Aral, Cosimo De Bari, Andrew W. McCaskie, Pamela G. Robey, Simón Méndez-Ferrer
The autonomic nervous system is a master regulator of homeostatic processes and stress responses. Sympathetic noradrenergic nerve fibers decrease bone mass, but the role of cholinergic signaling in bone has remained largely unknown. Here, we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca12c9aaa18370fb305c74b24f72ea7b
https://api.elsevier.com/content/abstract/scopus_id/85127354047
https://api.elsevier.com/content/abstract/scopus_id/85127354047
Autor:
Maximillian Berenschot, Jonathan R. Keller, Stephen J. Lockett, Shweta Singh, Tanmoy Sarkar, Brad Jakubison, Satyendra K. Singh, Stephen Gadomski, Kristbjorn O. Gudmundsson, Kimberly D. Klarmann, Steven Seaman
Publikováno v:
Cell Rep
Cell Reports, Vol 31, Iss 4, Pp-(2020)
Cell Reports, Vol 31, Iss 4, Pp-(2020)
Summary: Investigating mechanisms that regulate endothelial cell (EC) growth and survival is important for understanding EC homeostasis and how ECs maintain stem cell niches. We report here that targeted loss of Id genes in adult ECs results in dilat
Autor:
Shweta Singh, Satyendra K. Singh, Lei Sun, Xiongfong Chen, Lino Tessarollo, Serguei Kozlov, Jonathan R. Keller, Alexander Pfannenstein, Kimberly D. Klarmann, Stephen Gadomski, Valentin Magidson
Publikováno v:
Cell Stem Cell. 23:252-265.e8
Defining mechanisms that maintain tissue stem cells during homeostasis, stress, and aging is important for improving tissue regeneration and repair and enhancing cancer therapies. Here, we show that Id1 is induced in hematopoietic stem cells (HSCs) b