Zobrazeno 1 - 10
of 675
pro vyhledávání: '"Stephen G. Swisher"'
Autor:
Apar Pataer, MD, PhD, Annikka Weissferdt, MD, Arlene M. Correa, PhD, Ara A. Vaporciyan, MD, Boris Sepesi, MD, John V. Heymach, MD, Sabina Berezowska, MD, Tina Cascone, MD, Stephen G. Swisher, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 11, Pp 100420- (2022)
Introduction: Complete pathologic response (CPR) is an acceptable surrogate for survival in clinical trials but it occurs infrequently in patients with NSCLC receiving neoadjuvant chemotherapy (NCT). Therefore, we studied the impact of major patholog
Externí odkaz:
https://doaj.org/article/f35612be06cf4d75bebb3778e0ad2af2
Autor:
Tina Cascone, Annikka Weissferdt, Myrna C. B. Godoy, William N. William, Cheuk H. Leung, Heather Y. Lin, Sreyashi Basu, Shalini S. Yadav, Apar Pataer, Kyle G. Mitchell, Md Abdul Wadud Khan, Yushu Shi, Cara Haymaker, Luisa M. Solis, Edwin R. Parra, Humam Kadara, Ignacio I. Wistuba, Padmanee Sharma, James P. Allison, Nadim J. Ajami, Jennifer A. Wargo, Robert R. Jenq, Don L. Gibbons, J. Jack Lee, Stephen G. Swisher, Ara A. Vaporciyan, John V. Heymach, Boris Sepesi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Granulomatous/sarcoid-like lesions have been reported in patients treated with immune checkpoint inhibitors (ICIs). Here the authors report the occurrence of “nodal immune flare”, an apparent radiological cancer progression in the nodes character
Externí odkaz:
https://doaj.org/article/02f55269e7f9462fb8c8389a4b130848
Autor:
Mara B. Antonoff, MD, Hope A. Feldman, MD, Kyle G. Mitchell, MD, Ahsan Farooqi, MD, Ethan B. Ludmir, MD, Wayne L. Hofstetter, MD, Reza J. Mehran, MD, Ravi Rajaram, MD, David C. Rice, MB, BCh, Boris Sepesi, MD, Stephen G. Swisher, MD, Garrett L. Walsh, MD, Saumil Gandhi, MD, PhD, Daniel R. Gomez, MD, Ara A. Vaporciyan, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 3, Pp 100288- (2022)
Introduction: Pulmonary resection has been established as an important component of local consolidative therapy (LCT) for oligometastatic NSCLC. However, technical aspects of such surgical procedures have not been well characterized. We sought to rev
Externí odkaz:
https://doaj.org/article/ee6f50b61b9044f28752ebe8d6af6823
Autor:
Manoop S. Bhutani, Shamim Ejaz, Irina M. Cazacu, Ben S. Singh, Mehnaz Shafi, John R. Stroehlein, Reza J. Mehran, Garrett Walsh, Ara Vaporciyan, Stephen G. Swisher, Wayne Hofstetter
Publikováno v:
Cancers, Vol 14, Iss 23, p 5743 (2022)
Patients with esophageal cancer undergoing esophagectomy have an improved survival over time, however adverse events associated with the use of a gastric conduit are increasingly being reported. Delayed gastric emptying (DGE) is an esophagectomy-rela
Externí odkaz:
https://doaj.org/article/8a4f4a5fa7c341cd93530137dccb28b4
Autor:
Xin Hu, Junya Fujimoto, Lisha Ying, Junya Fukuoka, Kazuto Ashizawa, Wenyong Sun, Alexandre Reuben, Chi-Wan Chow, Nicholas McGranahan, Runzhe Chen, Jinlin Hu, Myrna C. Godoy, Kazuhiro Tabata, Kishio Kuroda, Lei Shi, Jun Li, Carmen Behrens, Edwin Roger Parra, Latasha D. Little, Curtis Gumbs, Xizeng Mao, Xingzhi Song, Samantha Tippen, Rebecca L. Thornton, Humam Kadara, Paul Scheet, Emily Roarty, Edwin Justin Ostrin, Xu Wang, Brett W. Carter, Mara B. Antonoff, Jianhua Zhang, Ara A. Vaporciyan, Harvey Pass, Stephen G. Swisher, John V. Heymach, J. Jack Lee, Ignacio I. Wistuba, Waun Ki Hong, P. Andrew Futreal, Dan Su, Jianjun Zhang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
There has been a drastic increase in detection of lung nodules, many of which are precancers, preinvasive, minimally invasive or sometimes invasive lung cancers. Here, Hu et al. perform multi-region exome sequencing to discern the evolutional traject
Externí odkaz:
https://doaj.org/article/6c98a1e227804a168c18ce27f945729f
Autor:
Xingxiang Pu, Ran Zhang, Li Wang, Yungchang Chen, Yi Xu, Apar Pataer, Ismail M. Meraz, Xiaoshan Zhang, Shuhong Wu, Lin Wu, Dan Su, Weimin Mao, John V. Heymach, Jack A. Roth, Stephen G. Swisher, Bingliang Fang
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background Because patient-derived xenografts (PDXs) are grown in immunodeficient mouse strains, PDXs are regarded as lacking an immune microenvironment. However, whether patients’ immune cells co-exist in PDXs remains uncharacterized. Met
Externí odkaz:
https://doaj.org/article/6894e6771c634171aa7604d1ac710e1d
Autor:
Edwin R. Parra, Pamela Villalobos, Carmen Behrens, Mei Jiang, Apar Pataer, Stephen G. Swisher, William N. William, Jiexin Zhang, Jack Lee, Tina Cascone, John V. Heymach, Marie-Andrée Forget, Cara Haymaker, Chantale Bernatchez, Neda Kalhor, Annikka Weissferdt, Cesar Moran, Jianjun Zhang, Ara Vaporciyan, Don L. Gibbons, Boris Sepesi, Ignacio I. Wistuba
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-11 (2018)
Abstract Background The clinical efficacy observed with inhibitors of programed cell death 1/programed cell death ligand 1 (PD-L1/PD-1) in cancer therapy has prompted studies to characterize the immune response in several tumor types, including lung
Externí odkaz:
https://doaj.org/article/a0fbee6e3c0d4cdda806783e081be8ef
Autor:
Xin Hu, Junya Fujimoto, Lisha Ying, Junya Fukuoka, Kazuto Ashizawa, Wenyong Sun, Alexandre Reuben, Chi-Wan Chow, Nicholas McGranahan, Runzhe Chen, Jinlin Hu, Myrna C. Godoy, Kazuhiro Tabata, Kishio Kuroda, Lei Shi, Jun Li, Carmen Behrens, Edwin Roger Parra, Latasha D. Little, Curtis Gumbs, Xizeng Mao, Xingzhi Song, Samantha Tippen, Rebecca L. Thornton, Humam Kadara, Paul Scheet, Emily Roarty, Edwin Justin Ostrin, Xu Wang, Brett W. Carter, Mara B. Antonoff, Jianhua Zhang, Ara A. Vaporciyan, Harvey Pass, Stephen G. Swisher, John V. Heymach, J. Jack Lee, Ignacio I. Wistuba, Waun Ki Hong, P. Andrew Futreal, Dan Su, Jianjun Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/65cbdc5d34a842e5a0fd745c093e43dc
Autor:
Anhui Shi, MD, Zhongxing Liao, MD, Pamela K. Allen, PhD, Linus Ho, MD, PhD, Mariela Blum Murphy, MD, Dipen M. Maru, MD, Stephen G. Swisher, MD, Wayne L. Hofstetter, MD, Reza J. Mehran, MD, James D. Cox, MD, Ritsuko Komaki, MD, Steven H. Lin, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 2, Iss 3, Pp 316-324 (2017)
Purpose: In patients with esophageal cancer (EC), intensity modulated radiation therapy (IMRT) improves dose sparing to the heart and lung, with some evidence showing clinical benefit. Herein, we report our cumulative clinical experience with the use
Externí odkaz:
https://doaj.org/article/ead571cd6568456f82605d3d8bd8a45b
Autor:
Maithili P. Dalvi, Lei Wang, Rui Zhong, Rahul K. Kollipara, Hyunsil Park, Juan Bayo, Paul Yenerall, Yunyun Zhou, Brenda C. Timmons, Jaime Rodriguez-Canales, Carmen Behrens, Barbara Mino, Pamela Villalobos, Edwin R. Parra, Milind Suraokar, Apar Pataer, Stephen G. Swisher, Neda Kalhor, Natarajan V. Bhanu, Benjamin A. Garcia, John V. Heymach, Kevin Coombes, Yang Xie, Luc Girard, Adi F. Gazdar, Ralf Kittler, Ignacio I. Wistuba, John D. Minna, Elisabeth D. Martinez
Publikováno v:
Cell Reports, Vol 19, Iss 8, Pp 1669-1684 (2017)
Although non-small cell lung cancer (NSCLC) patients benefit from standard taxane-platin chemotherapy, many relapse, developing drug resistance. We established preclinical taxane-platin-chemoresistance models and identified a 35-gene resistance signa
Externí odkaz:
https://doaj.org/article/b799525f4c5f4794b566dfe7987f5ae9