Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stephen G. Hastings"'
Autor:
Leslie M. Werbel, T. E. Mertz, C. S. Stratton, R. W. Fleming, T. J. Steffe, Stephen G. Hastings, L. T. Blouin, Milton L. Hoefle, J. M. Hinkley
Publikováno v:
Journal of medicinal chemistry. 34(1)
A series of alpha-[(diarylmethoxy)methyl]-1-piperidineethanols was evaluated for antiarrhythmic activity in the coronary artery ligated dog model. Structure-activity relationship studies indicated that the 2,6-dimethylpiperidine group afforded the be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2380bf40f1b914b1bfd0dfb905b675
https://pubmed.ncbi.nlm.nih.gov/1992154
https://pubmed.ncbi.nlm.nih.gov/1992154
Autor:
Milton L. Hoefle, R. W. Fleming, C. S. Stratton, T. E. Mertz, Stephen G. Hastings, T. J. Steffe, J. M. Hinkley, L. T. Blouin
Publikováno v:
Journal of medicinal chemistry. 34(1)
A series of alpha,alpha-diaryl-1-piperidinebutanols was evaluated for antiarrhythmic activity in the coronary ligated dog model. Structure-activity relationship studies indicated that the 2,6-dimethylpiperidine group yielded compounds with the best a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323324628858f116ba17616191eeccb8
https://pubmed.ncbi.nlm.nih.gov/1992110
https://pubmed.ncbi.nlm.nih.gov/1992110
Autor:
Charlotte D. Stratton, Milton L. Hoefle, Ruth M. Corey, Robert F. Meyer, Ann Holmes, Stephen G. Hastings
Publikováno v:
Chemischer Informationsdienst. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b55f04f2cefdef1a2767494238c7530e
https://doi.org/10.1002/chin.197524227
https://doi.org/10.1002/chin.197524227
Autor:
Charlotte D. Stratton, Milton L. Hoefle, Ruth M. Corey, Robert F. Meyer, Stephen G. Hastings, Ann Holmes
Publikováno v:
Journal of medicinal chemistry. 18(2)
A series of 1-amino-3-aryloxy-2-propanols has been synthesized and examined for cardioselective beta-blockade. The introduction of the (3,4-dimethoxyphenethyl)amino group lead to the most cardioselective agents. Structure-activity relationships are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e2f75b8d75a6e54ca00d8d4a57fba0
https://pubmed.ncbi.nlm.nih.gov/235644
https://pubmed.ncbi.nlm.nih.gov/235644
Publikováno v:
Chemischer Informationsdienst. 5
Eine Reihe von Methylheterocyclen (I) wird in Form ihrer Lithiumderivate (II) mit den Aminoacetonitrilen (III) zu den Enaminen (IV) umgesetzt, die durch Hydrolyse, Reduktion mit Natriumborhydrid und hydrierende Debenzylierung in Propanolamine (VII) u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5195af896cf69343101b6ec6e4b234c8
https://doi.org/10.1002/chin.197404242
https://doi.org/10.1002/chin.197404242
Publikováno v:
Journal of medicinal chemistry. 16(10)
Eine Reihe von Methylheterocyclen (I) wird in Form ihrer Lithiumderivate (II) mit den Aminoacetonitrilen (III) zu den Enaminen (IV) umgesetzt, die durch Hydrolyse, Reduktion mit Natriumborhydrid und hydrierende Debenzylierung in Propanolamine (VII) u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af3cf1ee29a3627eea00bef1774cb2c
https://pubmed.ncbi.nlm.nih.gov/4147942
https://pubmed.ncbi.nlm.nih.gov/4147942
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 122(1)
SummaryPostnatal changes in the cardiac ventricles of 75 piglets are reported. The RV/T ratio reclines from a mean of 0.382 to 0.253 by 7 days of age. Concomitant with this decline the LV + S/T and the LV/RV ratios increased. Although such changes oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36845083ffe002341a23a476239870a
https://pubmed.ncbi.nlm.nih.gov/5944870
https://pubmed.ncbi.nlm.nih.gov/5944870