Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Stephen G. Grant"'
Autor:
Ali F. Almutairy, Abdullah S. Alhamed, Stephen G. Grant, Miranda J. Falso, Billy W. Day, Colton R. Simmons, Jean J. Latimer
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionBreast cancer (BC) is the most common cancer affecting women in the United States. Ductal carcinoma in situ (DCIS) is the earliest identifiable pre-invasive BC lesion. Estimates show that 14 to 50% of DCIS cases progress to invasive BC.Me
Externí odkaz:
https://doaj.org/article/c4c90ea8dbcc4d48ad9f8cd113153a3d
Nucleotide excision repair is a predictor of early relapse in pediatric acute lymphoblastic leukemia
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-11 (2018)
Abstract Background Nucleotide Excision Repair (NER) is a major pathway of mammalian DNA repair that is associated with drug resistance and has not been well characterized in acute lymphoblastic leukemia (ALL). The objective of this study was to expl
Externí odkaz:
https://doaj.org/article/30efcfb3989140a18028ce27263b03f8
Autor:
Peter Wend, Stephanie Runke, Korinna Wend, Brenda Anchondo, Maria Yesayan, Meghan Jardon, Natalie Hardie, Christoph Loddenkemper, Ilya Ulasov, Maciej S. Lesniak, Rebecca Wolsky, Laurent A. Bentolila, Stephen G. Grant, David Elashoff, Stephan Lehr, Jean J. Latimer, Shikha Bose, Husain Sattar, Susan A. Krum, Gustavo A. Miranda‐Carboni
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 2, Pp 264-279 (2013)
Abstract Wnt/β‐catenin signalling has been suggested to be active in basal‐like breast cancer. However, in highly aggressive metastatic triple‐negative breast cancers (TNBC) the role of β‐catenin and the underlying mechanism(s) for the aggr
Externí odkaz:
https://doaj.org/article/bfd88c16d16f4a579876003647e84448
Autor:
Kimberly Sullivan, Maria Abreu, Stefanie Sveiven, Nancy G. Klimas, Abdullah Alhamed, Ali Almutairy, Stephen G. Grant, Jean Johanna Latimer
Publikováno v:
Military Medicine
IntroductionVeterans of the 1991 Gulf War were potentially exposed to a mixture of stress, chemicals and radiation that may have contributed to the persistent symptoms of Gulf War Illness (GWI). The genotoxic effects of some of these exposures are me
Autor:
Ali Almutairy, Abdullah Alhamed, Stephen G. Grant, Miranda Sarachine Falso, Billy W. Day, Jean J. Latimer
Publikováno v:
Cancer Research. 82:A033-A033
Background and Objectives: In 2021 breast cancer (BC) was the most common cancer affecting women and the second deadliest cancer in the U.S. Ductal Carcinoma In Situ (DCIS) is the earliest identifiable pre-invasive breast cancer lesion. Approximately
Autor:
Jean Johanna Latimer, Xiao-Lu Jin, Kimberly Sullivan, Omar Ibrahim, Stephen G. Grant, Nancy G. Klimas
Publikováno v:
Life Sciences. 281:119746
Aims Gulf War illness (GWI) is thought to be associated with exposures experienced by soldiers deployed in the 1991 Gulf War. A major question is how these exposures continue to influence the health of these individuals three decades later. One poten
Autor:
Stephanie Runke, David Elashoff, Ilya V. Ulasov, Husain Sattar, Susan A. Krum, Christoph Loddenkemper, Brenda Anchondo, Rebecca J. Wolsky, Shikha Bose, Gustavo A. Miranda-Carboni, Korinna Wend, Maciej S. Lesniak, Natalie Hardie, Stephan Lehr, Laurent A. Bentolila, Stephen G. Grant, Meghan Jardon, Jean Johanna Latimer, Peter Wend, Maria Yesayan
Publikováno v:
EMBO Molecular Medicine
Wnt/β-catenin signalling has been suggested to be active in basal-like breast cancer. However, in highly aggressive metastatic triple-negative breast cancers (TNBC) the role of β-catenin and the underlying mechanism(s) for the aggressiveness of TNB
Autor:
Amal Kanbour-Shakir, Jennifer Johnson, Tiffany D Miles, Kelly A. Beaudry-Rodgers, Stephen G. Grant, Jean Johanna Latimer, Victor G. Vogel, Ronald Johnson, Joseph L. Kelley, Nancy A. lalanne, Crystal M Kelly
Publikováno v:
Proceedings of the National Academy of Sciences. 107:21725-21730
The molecular etiology of breast cancer has proven to be remarkably complex. Most individual oncogenes are disregulated in only approximately 30% of breast tumors, indicating that either very few molecular alterations are common to the majority of br
Autor:
Stephen G. Grant
Publikováno v:
The Open Pediatric Medicine Journal. 4:10-13
Maternal exposure to tobacco smoke is known to have deleterious effects on the developing fetus, but it has only recently been shown that there may be life-long consequences due to genotoxic damage. Analysis of newborn cord bloods with the GPA somati
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 26:378-385
(Z)-1-1-Dichloro-2,3-diphenylcyclopropane (A(II)) and (Z)-1,1-dichloro-2-(4-methoxyphenyl)-3-phenylcyclopropane [2-(4-methoxyphenyl)-A(II)] inhibit tubulin polymerization, PSA production, and the proliferation of human prostate cancer cells. The acti