Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen G Malin"'
Autor:
Osman Ahmed, April S. Caravaca, Maria Crespo, Wanmin Dai, Ting Liu, Qi Guo, Magdalena Leiva, Guadalupe Sabio, Vladimir S. Shavva, Stephen G. Malin, Peder S. Olofsson
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Background The liver is an important immunological organ and liver inflammation is part of the pathophysiology of non-alcoholic steatohepatitis, a condition that may promote cirrhosis, liver cancer, liver failure, and cardiovascular disease.
Externí odkaz:
https://doaj.org/article/9da48cf905954ac6b4d0687c31190809
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
B cells are a core element of the pathophysiology of atherosclerotic cardiovascular disease (ASCVD). Multiple experimental and epidemiological studies have revealed both protective and deleterious functions of B cells in atherosclerotic plaque format
Externí odkaz:
https://doaj.org/article/2a6f141d070f4395af6b513af6389b0c
Autor:
Alessandro L. Gallina, Urszula Rykaczewska, Robert C. Wirka, April S. Caravaca, Vladimir S. Shavva, Mohamad Youness, Glykeria Karadimou, Mariette Lengquist, Anton Razuvaev, Gabrielle Paulsson-Berne, Thomas Quertermous, Anton Gisterå, Stephen G. Malin, Laura Tarnawski, Ljubica Matic, Peder S. Olofsson
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Objectives and Aims: Vascular smooth muscle cells (VSMCs) are key constituents of both normal arteries and atherosclerotic plaques. They have an ability to adapt to changes in the local environment by undergoing phenotypic modulation. An improved und
Externí odkaz:
https://doaj.org/article/00172a729ab44f2ab228b984782249c7
Autor:
Laura Tarnawski, Vladimir S. Shavva, Eric J. Kort, Zhengbing Zhuge, Ingrid Nilsson, Alessandro L. Gallina, David Martínez-Enguita, Benjamin Heller Sahlgren, Matthew Weiland, April S. Caravaca, Staffan Schmidt, Ping Chen, Katarina Abbas, Fu-Hua Wang, Osman Ahmed, Michael Eberhardson, Anna Färnert, Eddie Weitzberg, Mika Gustafsson, Jan Kehr, Stephen G. Malin, Henrik Hult, Mattias Carlström, Stefan Jovinge, Peder S. Olofsson
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Endothelial dysfunction and impaired vasodilation are linked with adverse cardiovascular events. T lymphocytes expressing choline acetyltransferase (ChAT), the enzyme catalyzing biosynthesis of the vasorelaxant acetylcholine (ACh), regulate vasodilat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cb681031febe45afd788f72d0012010
https://doi.org/10.1073/pnas.2212476120
https://doi.org/10.1073/pnas.2212476120
Autor:
Sanna Hellberg, Osman Ahmed, Yuyang Zhang, Giada Di Nunzio, Hanna M Björck, Roy Francis, Linn Fagerberg, Anton Gisterå, Xueming Zhang, Jari Metso, Valentina Manfé, Yosdel Soto, Anders Franco-Cereceda, Per Eriksson, Matti Jauhiainen, Peder S. Olofsson, Stephen G. Malin
Apolipoprotein-B (APOB) containing lipoproteins are causative for atherosclerotic cardiovascular disease. Whether the vasculature is the initial responding site or if atherogenic-dyslipidemia effects other organs simultaneously is unknown. We set out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2698f270010d9aa1764311ad0c4afc65
https://doi.org/10.1101/2022.10.13.512086
https://doi.org/10.1101/2022.10.13.512086
Autor:
Sabine Jurado, Anna S Fedl, Markus Jaritz, Daniela Kostanova‐Poliakova, Stephen G Malin, Charles G Mullighan, Sabine Strehl, Maria Fischer, Meinrad Busslinger
Publikováno v:
The EMBO journal. 41(7)
While PAX5 is an important tumor suppressor gene in B-cell acute lymphoblastic leukemia (B-ALL), it is also involved in oncogenic translocations coding for diverse PAX5 fusion proteins. PAX5-JAK2 encodes a protein consisting of the PAX5 DNA-binding r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e2c9bf2050a70a3f8ba7612cbcf697
https://pubmed.ncbi.nlm.nih.gov/35156727
https://pubmed.ncbi.nlm.nih.gov/35156727
Autor:
Myrthe E Reiche, Oom Pattarabajinard, Aditi Upadhye, Kikkie Poels, Claudia van Tiel, Stephen G Malin, Christoph J Binder, Norbert Gerdes, Christian Weber, Dorothee Atzler, Coleen A McNamara, Esther Lutgens
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Background: The co-stimulatory CD40-CD40L dyad is an important driver of atherosclerosis. CD40 exerts divergent, cell-specific roles, which differentially impacts atherogenesis. Objectives: We here investigate the role of the most prominent CD40-expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6425deed45d51cacc5922acffa4d785
https://doi.org/10.1161/atvb.41.suppl_1.101
https://doi.org/10.1161/atvb.41.suppl_1.101
Autor:
Saikiran K, Sedimbi, Thomas, Hägglöf, Manasa G, Garimella, Shan, Wang, Amanda, Duhlin, Ana, Coelho, Katrine, Ingelshed, Emma, Mondoc, Stephen G, Malin, Rikard, Holmdahl, David P, Lane, Elizabeth A, Leadbetter, Mikael C I, Karlsson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance iNKT cells can both provide help and inhibit B cell responses. Our data show that when iNKT cells are activated with the glycolipid agonist αGalCer together with the inflammatory cytokine IL-18, they switch from regulating autoreactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::179745744349a79c823e24b2f7cc8bdb
https://pubmed.ncbi.nlm.nih.gov/32295878
https://pubmed.ncbi.nlm.nih.gov/32295878