Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Stephen G Holt"'
Publikováno v:
Saudi Journal of Kidney Diseases and Transplantation, Vol 33, Iss 3, Pp 413-417 (2022)
Some epidemiological data have implicated blood groups in susceptibility to coronavirus disease 2019 (COVID-19) infection. We were interested to see if there was any apparent effect of different ABO blood groups on susceptibility to COVID-19 infectio
Externí odkaz:
https://doaj.org/article/a3b2828cc2684b24ba7791f9ef0d5cfd
Publikováno v:
JBMR Plus, Vol 5, Iss 6, Pp n/a-n/a (2021)
ABSTRACT Patients with chronic inflammatory diseases (CID) experience accelerated loss of bone mineral density, which is often accompanied by increased vascular calcification. These disturbances can be attenuated by therapies for inflammation, such a
Externí odkaz:
https://doaj.org/article/76e61497107346a191b081a97c637320
Autor:
Sven-Jean Tan, Melissa M Chu, Nigel D Toussaint, Michael MX Cai, Tim D Hewitson, Stephen G Holt
Publikováno v:
Journal of Circulating Biomarkers, Vol 7 (2018)
The recently discovered klotho proteins have roles in a diverse range of metabolic processes with the oldest protein, α-klotho, implicated in various cellular pathways in energy, glucose, and phosphate metabolism. Circulating soluble klotho (sKl), d
Externí odkaz:
https://doaj.org/article/61ee42cae4854e2ba3518ff0cb7fc2d2
Publikováno v:
Journal of Renal and Hepatic Disorders, Vol 2, Iss 2 (2018)
Tenofovir disoproxil fumarate (TDF) is a common antiretroviral utilised in the treatment of human immunodeficiency virus (HIV) and hepatitis B infections. It is associated with the development of tubulotoxicity and tubulopathies, and is not recommend
Externí odkaz:
https://doaj.org/article/7368840b7ccf4c4cb42ecb938751d635
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
The close association between cardiovascular pathology and renal dysfunction are well documented and significant. Patients with conventional risk factors for cardiovascular disease like diabetes and hypertension also suffer renal dysfunction. This is
Externí odkaz:
https://doaj.org/article/da6ba2b416844a6598b91ff854129755
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60904 (2013)
The formation of fetuin-A-containing calciprotein particles (CPP) may facilitate the clearance of calcium phosphate nanocrystals from the extracellular fluid. These crystals may otherwise seed extra-osseous mineralization. Fetuin-A is a partially pho
Externí odkaz:
https://doaj.org/article/e2f721cc191b4fd490355b82d6890c22
Autor:
Ursula Thiem, Tim D Hewitson, Nigel D Toussaint, Stephen G Holt, Maria C Haller, Andreas Pasch, Daniel Cejka, Edward R Smith
Publikováno v:
Nephrology Dialysis Transplantation. 38:1282-1296
Background Calciprotein particles (CPPs), colloidal mineral-protein nanoparticles, have emerged as potential mediators of phosphate toxicity in dialysis patients, with putative links to vascular calcification, endothelial dysfunction and inflammation
Autor:
Nigel D. Toussaint, Matthew J. Damasiewicz, Stephen G. Holt, Zhong X. Lu, Dianna J. Magliano, Robert C. Atkins, Steven J. Chadban, Jonathan E. Shaw, Kevan R. Polkinghorne
Publikováno v:
Journal of Renal Nutrition. 32:510-519
High dietary phosphate intake may lead to adverse outcomes including cardiovascular disease (CVD). Urinary phosphate excretion, a marker of intestinal phosphate absorption, may be a more reliable marker of phosphate homeostasis in steady state than s
Publikováno v:
American Journal of Nephrology. 53:806-815
Introduction: Elevated levels of fibroblast growth factor-23 (FGF23) in chronic kidney disease (CKD) are associated with progression of CKD. FGF23 inhibits proximal tubular phosphate reabsorption, raising phosphate concentrations in the tubular fluid
Autor:
Kate Wyburn, Stephen G Holt, Peter Hughes, Matthew P Sypek, Joshua Kausman, Narelle Watson, Philip A. Clayton
Publikováno v:
Transplantation. 105:1317-1325
BACKGROUND In March 2016, Australia's deceased donor kidney allocation program introduced calculated panel reactive antibody (cPRA) based on antibody exclusions using multiplex assays to define sensitization for waitlisted candidates. We aimed to ass