Zobrazeno 1 - 10
of 1 091
pro vyhledávání: '"Stephen G Davies"'
Autor:
Timothy J. Donohoe
Publikováno v:
Tetrahedron. 76:130748
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6005f7a46842f84599f9e9a2e07fad67
https://doi.org/10.1016/j.tet.2019.130748
https://doi.org/10.1016/j.tet.2019.130748
Autor:
Thomas R. Jackson, Aini Vuorinen, Laia Josa-Culleré, Katrina S. Madden, Daniel Conole, Thomas J. Cogswell, Isabel V.L. Wilkinson, Laura M. Kettyle, Douzi Zhang, Alison O’Mahony, Deanne Gracias, Lorna McCall, Robert Westwood, Georg C. Terstappen, Stephen G. Davies, Edward W. Tate, Graham M. Wynne, Paresh Vyas, Angela J. Russell, Thomas A. Milne
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104787- (2022)
Summary: Despite much progress in developing better drugs, many patients with acute myeloid leukemia (AML) still die within a year of diagnosis. This is partly because it is difficult to identify therapeutic targets that are effective across multiple
Externí odkaz:
https://doaj.org/article/41383f2f5a8d4ffeb2940ad8bb573d15
Publikováno v:
European Journal of Organic Chemistry; April 2010, Vol. 2010 Issue: 10 p1875-1884, 10p
Autor:
Mark Lautens
Publikováno v:
Journal of the American Chemical Society. 122:5904-5904
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7933a3bf58c4f3cde44bea63171e4472
https://doi.org/10.1021/ja995780u
https://doi.org/10.1021/ja995780u
Autor:
Laia Josa-Culleré, Thomas J. Cogswell, Irene Georgiou, Morgan Jay-Smith, Thomas R. Jackson, Carole J. R. Bataille, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. Russell
Publikováno v:
Molecules, Vol 26, Iss 21, p 6648 (2021)
Acute myeloid leukemia (AML) is the most aggressive type of blood cancer, and there is a continued need for new treatments that are well tolerated and improve long-term survival rates in patients. Induction of differentiation has emerged as a promisi
Externí odkaz:
https://doaj.org/article/371c3b38b9e44be49d8dc114324e28ce
Publikováno v:
Journal of Natural Products. 85:306-312
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::791a46d1b8046afba5d4d624282935bd
https://doi.org/10.1021/acs.jnatprod.1c00847
https://doi.org/10.1021/acs.jnatprod.1c00847
Autor:
David Reza, Rosalino Balo, Jose M. Otero, Ai M. Fletcher, Rebeca García-Fandino, Victor M. Sanchez-Pedregal, Stephen G. Davies, Ramon J. Estevez, Juan C. Estevez
We describe the synthesis of trihydroxylated cyclohexane β-amino acids from (–)-shikimic acid, in their cis and trans configuration, and the incorporation of the trans isomer into a trans-2-aminocyclohexanecarboxylic acid peptide chain. Subsequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::325ef2db0e5f65058856a31c77d0ff75
https://doi.org/10.26434/chemrxiv-2022-zdb5j
https://doi.org/10.26434/chemrxiv-2022-zdb5j
Autor:
Thomas A. Milne, Graham Trevitt, Stephen G. Davies, Douzi Zhang, Thomas R. Jackson, Angela J. Russell, Katrina S. Madden, Laia Josa-Culleré, Paresh Vyas, Graham Michael Wynne, Tom S. Carter, Thomas J. Cogswell
Publikováno v:
Journal of Medicinal Chemistry. 64:15608-15628
Induction of differentiation is a promising therapeutic strategy against acute myeloid leukemia. However, current differentiation therapies are effective only to specific patient populations. To identify novel differentiation agents with wider effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203e8ec83667a61e34f8c6a1755a1032
https://doi.org/10.1021/acs.jmedchem.1c00574
https://doi.org/10.1021/acs.jmedchem.1c00574
Publikováno v:
Journal of natural products. 85(7)
The first asymmetric synthesis of microgrewiapine C, a piperidine alkaloid isolated from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1c364d00a8d9c9b926519232ea4876
https://pubmed.ncbi.nlm.nih.gov/35771599
https://pubmed.ncbi.nlm.nih.gov/35771599