Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Stephen Futterweit"'
Autor:
Stephen Futterweit, John E. Bylander, Roy Mathew, Howard Trachtman, Antonio A. Tarectecan, Judith S. Bond, Elsa Valderrama
Publikováno v:
American Journal of Physiology-Renal Physiology. 289:F911-F921
Meprin (MEP) A is a metalloendopeptidase that is present in the renal proximal tubule brush-border membrane (BBM) and that colocalizes with angiotensin-converting enzyme (ACE). The MEP beta-chain gene locus on chromosome 18 has been linked to a heigh
Publikováno v:
Pediatric Nephrology. 17:20-29
Nitric oxide (NO) is a multifunctional mediator that has been implicated in the short-term hemodynamic alterations that occur in acute streptozocin (STZ)-induced diabetes. We investigated the role of NO produced by inducible nitric oxide synthase (iN
Publikováno v:
Biochemical and Biophysical Research Communications. 245:443-446
Vascular endothelial growth factor (VEGF) stimulates nitric oxide (NO) production by endothelial cells in vitro and in vivo. However, the impact of VEGF on inducible nitric oxide synthase (iNOS) activity and NO synthesis in cultured mesangial cells i
Autor:
Pravin C. Singhal, Nicholas Franki, Stephen Futterweit, Howard Trachtman, Robert Greenwald, Ashok R. Amin, Susan A. Moak
Publikováno v:
Biochemical and Biophysical Research Communications. 229:243-248
Tetracyclines inhibit matrix metalloproteinases (MMP) and attenuate connective tissue degradation in a wide variety of human and animal disorders. Chemically modified tetracyclines (CMT) have been synthesized in which the antibacterial potency has be
Autor:
James C.M. Chan, Elsa Valderrama, Chan Ma, Howard Trachtman, Winnie Chan, Paul E. Wakely, Richard B. Brandt, John K. Maesaka, Stephen Futterweit
Publikováno v:
Pediatric Research. 40:620-626
Vitamin E Ameliorates Renal Injury in an Experimental Model of Immunoglobulin A Nephropathy 1
Publikováno v:
Biochemical and Biophysical Research Communications. 218:704-708
We recently demonstrated that stimulation of inducible nitric oxide synthase (iNOS) activity reduced the accumulation of collagen and fibronectin in cultured rat mesangial cells. Therefore, we examined whether nitric oxide (NO) influenced the activit
Publikováno v:
Biochemical and Biophysical Research Communications. 207:120-125
Nitric oxide (NO) is an important effector molecule of the inflammatory response. It is synthesized by mesangial cells and has been proposed to contribute to glomerular injury in various disease states. We studied whether NO modulates extracellular m
Publikováno v:
Pediatric Research. 32:118-124
Taurine is an organic osmolyte in brain cells. We studied whether cerebral taurine transport is enhanced as part of the cell volume regulatory adaptation to hypernatremia. Hypernatremic dehydration was induced for 48 h. Synaptosomes, metabolically ac
Publikováno v:
Life Sciences. 49:677-688
To clarify the role of the sugar polyols, sorbitol and myo-inositol, in cerebral cell volume regulation, we studied the effect of sorbinil, an inhibitor of aldose and aldehyde reductase, on the size of the cerebral water compartments in rats with hyp
Autor:
Christopher Arzberger, Nicholas Franki, Howard Trachtman, Judah Goldschmiedt, Pravin C. Singhal, Stephen Futterweit, Jessica Bod, Haddassah Gorman, Krishna Reddy
Publikováno v:
Pediatric nephrology (Berlin, Germany). 21(5)
Background: C-reactive protein (CRP) has been linked to cardiovascular and renal disease. We evaluated the effects of CRP on the production of nitric oxide (NO) and superoxide by rat mesangial cells (RMC) and the impact on cell function. Methods and