Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen Forrow"'
Autor:
Anne Huber, Amr H. Allam, Christine Dijkstra, Stefan Thiem, Jennifer Huynh, Ashleigh R. Poh, Joshua Konecnik, Saumya P. Jacob, Rita Busuttil, Yang Liao, David Chisanga, Wei Shi, Mariah G. Alorro, Stephen Forrow, Daniele V.F. Tauriello, Eduard Batlle, Alex Boussioutas, David S. Williams, Michael Buchert, Matthias Ernst, Moritz F. Eissmann
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114616- (2024)
Summary: Although aberrant activation of the KRAS and PI3K pathway alongside TP53 mutations account for frequent aberrations in human gastric cancers, neither the sequence nor the individual contributions of these mutations have been clarified. Here,
Externí odkaz:
https://doaj.org/article/bcbb4c19d532433d8228119f5febdeda
Autor:
Thomas Mortimer, Valentina M. Zinna, Carmelo Laudanna, Paul Petrus, Kevin B. Koronowski, Jacob G. Smith, Carolina M. Greco, Elisa García-Lara, Arun Kumar, Mireia Vaca-Dempere, Oleg Deryagin, Stephen Forrow, Paolo Sassone-Corsi, Patrick-Simon Welz, Pura Muñoz-Cánoves, Salvador Aznar Benitah
In mammals, an integrated network of molecular oscillators drives daily rhythms of tissue-specific homeostatic processes. This network is required for maintaining health and can be compromised by physiological aging, disease, and lifestyle choices. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e68fd039a5ae2e6f8a866f31b9f70c3
https://doi.org/10.1101/2022.01.26.477844
https://doi.org/10.1101/2022.01.26.477844
Autor:
Aida Peña-Blanco, Travis H. Stracker, Lluís Palenzuela, Anja Groth, Brian Raught, Philip A. Knobel, Katrin Rein, Alain de Bruin, Julien Colombelli, Teresa López-Rovira, Sandra Segura-Bayona, Etienne Coyaud, Stephen Forrow, Sameh A. Youssef, Helena González-Burón
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Segura-Bayona, S, Knobel, P A, Gonzalez-Buron, H, Youssef, S A, Peña-Blanco, A, Coyaud, E, Lopez-Rovira, T, Rein, K, Palenzuela, L, Colombelli, J, Forrow, S, Raught, B, Groth, A, De Bruin, A & Stracker, T H 2017, ' Differential requirements for Tousled-like kinases 1 and 2 in mammalian development ', Cell Death and Differentiation, vol. 24, no. 11, pp. 1872-1885 . https://doi.org/10.1038/cdd.2017.108
Cell death and differentiation, 24(11), 1872-1885. Nature Publishing Group
Cell Death and Differentiation, 24(11), 1872. Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Segura-Bayona, S, Knobel, P A, Gonzalez-Buron, H, Youssef, S A, Peña-Blanco, A, Coyaud, E, Lopez-Rovira, T, Rein, K, Palenzuela, L, Colombelli, J, Forrow, S, Raught, B, Groth, A, De Bruin, A & Stracker, T H 2017, ' Differential requirements for Tousled-like kinases 1 and 2 in mammalian development ', Cell Death and Differentiation, vol. 24, no. 11, pp. 1872-1885 . https://doi.org/10.1038/cdd.2017.108
Cell death and differentiation, 24(11), 1872-1885. Nature Publishing Group
Cell Death and Differentiation, 24(11), 1872. Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
instname
The regulation of chromatin structure is critical for a wide range of essential cellular processes. The Tousled-like kinases, TLK1 and TLK2, regulate ASF1, a histone H3/H4 chaperone, and likely other substrates, and their activity has been implicated
Autor:
Kenneth A. Brown, Trond Aasen, Malcolm B. Hodgins, David A. Greenhalgh, Malcolm E. Finbow, Laurence Tetley, Sheila Bryson, George Bakirtzis, Leonard Shore, Rukhsana Choudhry, Stephen Forrow
Publikováno v:
Human Molecular Genetics. 12:1737-1744
To investigate the role of connexins in dominantly inherited skin disease, transgenic mice were produced which expressed mutant connexin 26 [gjb2/connexin 26(D66H)], from a keratin 10 promoter, exclusively in the suprabasal epidermis (the cells in wh
Autor:
Susana Ros, Delia Zafra, Stephen Forrow, Jordi Valles-Ortega, Joan J. Guinovart, Mar García-Rocha, Jorge Domínguez, Joaquim Calbó
Publikováno v:
The Journal of biological chemistry. 285(48)
In this study, we tested the efficacy of increasing liver glycogen synthase to improve blood glucose homeostasis. The overexpression of wild-type liver glycogen synthase in rats had no effect on blood glucose homeostasis in either the fed or the fast
Autor:
Robert J. B. Nibbs, Heinrich Körner, Mark D. Bunting, Sarah Haylock-Jacobs, Iain Comerford, Wendel Litchfield, Yuka Harata-Lee, Shaun R. McColl, Stephen Forrow
Publikováno v:
Blood. 116(20)
Our previous in vitro studies led to proposals that the atypical chemokine receptor CCX-CKR is a scavenger of CCR7 ligand homeostatic chemokines. In the present study, we generated CCX-CKR−/− mice and confirm this scavenger function in vivo. Comp
Autor:
David Stevenson, Michael F. Olson, Michael S. Samuel, Sheila Bryson, June Munro, Stephen Forrow
ROCK kinases regulate actin-myosin structures downstream of Rho GTPases. We generated mice expressing 4-hydroxytamoxifen (4HT)-regulated human ROCK II (ROCKII:mER) under the transcriptional control of the cytokeratin14 (K14) promoter. The K14-ROCKII:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ba15d458c1f04ebf03804db780dc79
https://hdl.handle.net/1959.8/154811
https://hdl.handle.net/1959.8/154811
Autor:
Trond Aasen, Malcolm B. Hodgins, Sheila Bryson, David A. Greenhalgh, Susan Jamieson, Malcolm E. Finbow, George Bakirtzis, Stephen Forrow, Laurence Tetley
Publikováno v:
CIÊNCIAVITAE
Scopus-Elsevier
Europe PubMed Central
Scopus-Elsevier
Europe PubMed Central
To elucidate the mode of action of dominant mutant connexins in causing inherited skin diseases, transgenic mice were produced that express the true Vohwinkel syndrome-associated mutant Cx26 (D66H), from a keratin 10 promoter, specifically in the sup