Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Stephen F. Parsons"'
Publikováno v:
Haematologica, Vol 102, Iss 3 (2017)
The generation of cultured red blood cells from stem cell sources may fill an unmet clinical need for transfusion-dependent patients, particularly in countries that lack a sufficient and safe blood supply. Cultured red blood cells were generated from
Externí odkaz:
https://doaj.org/article/3225d7ca54204b26b3f5b1764fd7baa8
Autor:
Frances A Spring, Rebecca E Griffiths, Tosti J Mankelow, Christopher Agnew, Stephen F Parsons, Joel A Chasis, David J Anstee
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62654 (2013)
The proliferation and terminal differentiation of erythroid progenitors occurs in human bone marrow within erythroblastic islands, specialised structures consisting of a central macrophage surrounded by developing erythroid cells. Many cell-cell and
Externí odkaz:
https://doaj.org/article/994732caaaa14d64903e94486a5c0542
Publikováno v:
Haematologica. 102:476-483
The generation of cultured red blood cells from stem cell sources may fill an unmet clinical need for transfusion-dependent patients, particularly in countries that lack a sufficient and safe blood supply. Cultured red blood cells were generated from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb383fa2c0247b14ea80b52cfdfc5c52
https://doi.org/10.3324/haematol.2016.154443
https://doi.org/10.3324/haematol.2016.154443
Publikováno v:
Autophagy. 9:881-893
Wholesale depletion of membrane organelles and extrusion of the nucleus are hallmarks of mammalian erythropoiesis. Using quantitative EM and fluorescence imaging we have investigated how autophagy contributes to organelle removal in an ex vivo model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197fec5ccd8028c7585d854fbf3f4c88
https://doi.org/10.4161/auto.24172
https://doi.org/10.4161/auto.24172
Publikováno v:
Haematologica
The generation of cultured red blood cells from stem cell sources may fill an unmet clinical need for transfusion-dependent patients, particularly in countries that lack a sufficient and safe blood supply. Cultured red blood cells were generated from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72205eed2447f063751c34a5d577822f
https://pubmed.ncbi.nlm.nih.gov/27909219
https://pubmed.ncbi.nlm.nih.gov/27909219
Autor:
Belinda K. Singleton, Stephen F. Parsons, Geoff Daniels, Carole Green, D J Anstee, Vanja Karamatic Crew
Publikováno v:
British Journal of Haematology. 142:657-667
Tn polyagglutination results from inactivating mutations in C1GALT1C1, an X-borne gene encoding a core 1 beta3-galactosyltransferase-specific molecular chaperone (cosmc) required for the functioning of T-synthase (beta 1,3-galactosyltransferase), a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f6cd0dbc0a87f3613dc0b12847acb08
https://doi.org/10.1111/j.1365-2141.2008.07215.x
https://doi.org/10.1111/j.1365-2141.2008.07215.x
Autor:
Stephen F. Parsons, Punthita Sakuntanaga, Ryo Kurita, Jan Frayne, David J. Anstee, Yukio Nakamura, Marieangela C. Wilson, Kongtana Trakarnsanga, Winnie W. Y. Lau, Belinda K. Singleton
Publikováno v:
University of Bristol-PURE
A major barrier to the clinical use of erythrocytes generated in vitro from pluripotent stem cells or cord blood progenitors is failure of these erythrocytes to express adult hemoglobin. The key regulators of globin switching KLF1 and BCL11A are abse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af529a0d38f86ae8aa6320087b8e3cb
https://europepmc.org/articles/PMC4222483/
https://europepmc.org/articles/PMC4222483/
Autor:
Stephen F. Parsons, Edward D. Salmon
Publikováno v:
Cell Motility and the Cytoskeleton. 36:1-11
Crude cytoplasmic extracts made from Xenopus eggs have proven to be uniquely useful in the studies of the mechanism of spindle microtubule assembly dynamics and chromosome movement during progression through the cell cycle. We examined microtubule dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7df68c074c8c90efb2046bf888099c4b
https://doi.org/10.1002/(sici)1097-0169(1997)36:1<1::aid-cm1>3.0.co
https://doi.org/10.1002/(sici)1097-0169(1997)36:1<1::aid-cm1>3.0.co
Autor:
Jon D. Lane, Kongtana Trakarnsanga, Rebecca E. Griffiths, David J. Anstee, Nicola Cogan, Tosti J. Mankelow, Stephen F. Parsons, Sabine Kupzig, Virginie M S Betin, Edwin Massey
Publikováno v:
Blood. 119(26)
The maturation of reticulocytes into functional erythrocytes is a complex process requiring extensive cytoplasmic and plasma membrane remodeling, cytoskeletal rearrangements and changes to cellular architecture. Autophagy is implicated in the sequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927a3862b80b9b6dc9283d6ab34f81c0
https://pubmed.ncbi.nlm.nih.gov/22659916
https://pubmed.ncbi.nlm.nih.gov/22659916
Publikováno v:
Autophagy. 8(4)
The Atg4 cysteine proteases play crucial roles in the processing of Atg8 proteins during autophagy, but their regulation during cellular stress and differentiation remains poorly understood. We have found that two Atg4 family members--Atg4C and Atg4D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031da69cb85e70fbd683ef1749007ae9
https://pubmed.ncbi.nlm.nih.gov/22441018
https://pubmed.ncbi.nlm.nih.gov/22441018