Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Stephen F. Doran"'
Autor:
Nilam Vetal, Shama Ahmad, Nithya Mariappan, Pamela C. Powell, Stephen F. Doran, Aftab Ahmad, David A. Ford, Juan Xavier Masjoan Juncos, Wayne E. Bradley, Iram Zafar, Chih-Chang Wei, Sadis Matalon, William E. Louch, Ahmed Zaky, Louis J. Dell’Italia
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 316:H212-H223
Halogens are widely used, highly toxic chemicals that pose a potential threat to humans because of their abundance. Halogens such as bromine (Br2) cause severe pulmonary and systemic injuries; however, the mechanisms of their toxicity are largely unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70252210d4aa61e6ecab990f765e4d7c
https://doi.org/10.1152/ajpheart.00652.2017
https://doi.org/10.1152/ajpheart.00652.2017
Autor:
David A. Ford, Dylan R. Addis, James A. Mobley, Kyoko Kojima, Israr Ahmad, Stephen F. Doran, Ming-Yuan Jian, Saurabh Aggarwal, Sadis Matalon
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Bromine (Br2) is an organohalide found in nature and is integral to many manufacturing processes. Br2is toxic to living organisms, and high concentrations can prove fatal. To meet industrial demand, large amounts of purified Br2are produced, transpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7929db0c1992434cc9f751b984087606
https://pubmed.ncbi.nlm.nih.gov/32579402
https://pubmed.ncbi.nlm.nih.gov/32579402
Autor:
James A. Lambert, Stephen F. Doran, Saurabh Aggarwal, Sadis Matalon, Changchun Ren, Dylan R. Addis, Tamas Jilling
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Circulating levels of sFLT‐1 (soluble fms‐like tyrosine kinase 1), the extracellular domain of vascular endothelial growth factor (VEGF) receptor 1, and its ratio to levels of placental growth factor are markers of the occurrence and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98ed0864bc2e0679623761578aeb6ff
https://doi.org/10.1161/jaha.119.013238
https://doi.org/10.1161/jaha.119.013238
Autor:
Mandy Laube, Ahmed Lazrak, Judy Creighton, Sadis Matalon, Ming Yuan Jian, Zhihong Yu, Stephen F. Doran, Y. S. Prakash, Stavros Garantziotis
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 318(3)
We investigated the mechanisms involved in the development of airway hyperresponsiveness (AHR) following exposure of mice to halogens. Male mice (C57BL/6; 20–25 g) exposed to either bromine (Br2) or Cl2(600 or 400 ppm, respectively, for 30 min) dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47d8199bc5c23dde65c1dcfd8c2d1db
https://pubmed.ncbi.nlm.nih.gov/32384259
https://pubmed.ncbi.nlm.nih.gov/32384259
Autor:
Noor A. Ahmed, Namasivayam Ambalavanan, Muna Sapkota, Tamas Jilling, Adam Molyvdas, Kelsey Maclin, Carolyn J. Albert, Israr Ahmad, Saurabh Aggarwal, David A. Ford, Sadis Matalon, Ammar Saadoon Alishlash, Stephen F. Doran
Publikováno v:
Redox Biology
Redox Biology, Vol 44, Iss, Pp 102009-(2021)
Redox Biology, Vol 44, Iss, Pp 102009-(2021)
Triggering factors of Acute Chest Syndrome (ACS) is a leading cause of death in patients with Sickle Cell Disease (SCD) and targeted therapies are limited. Chlorine (Cl2) inhalation happens frequently, but its role as a potential trigger of ACS has n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9bf6783ed279d193a7da74409ceeaae
https://doi.org/10.1016/j.redox.2021.102009
https://doi.org/10.1016/j.redox.2021.102009
Publikováno v:
Toxicology Letters. 271:20-25
Chlorine (Cl2) gas exposure and toxicity remains a concern in military and industrial sectors. While post-Cl2 exposure damage to the lungs and other tissues has been documented and major underlying mechanisms elucidated, no targeted therapeutics that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde3fe60ed8cb20523f139a7a9c0fe80
https://doi.org/10.1016/j.toxlet.2017.02.019
https://doi.org/10.1016/j.toxlet.2017.02.019
Autor:
Namasivayam Ambalavanan, Saurabh Aggarwal, James A. Lambert, Louis J. Dell'Italia, Tamas Jilling, Rakesh P. Patel, Sadis Matalon, Stephen F. Doran, Wayne E. Bradley
Publikováno v:
A45. CRITICAL CARE: OF MICE AND MEN - INSIGHTS FROM EXPERIMENTAL AND ANIMAL MODELS IN ARDS AND SEPSIS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49a7b3965dfadc36fc081df3a4da43a2
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1706
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1706
Autor:
Judy Creighton, Stephen F. Doran, Israr Ahmad, Paul E. Wolkowicz, Saurabh Aggarwal, Ming Yuan Jian, Sadis Matalon, Ting Zhou
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a65c11ccf85d3d0e242add76cdc9e4c
https://doi.org/10.1096/fasebj.2019.33.1_supplement.127.12
https://doi.org/10.1096/fasebj.2019.33.1_supplement.127.12
Autor:
Tamas Jilling, Carolyn J. Albert, David A. Ford, Rakesh P. Patel, Mark Gillespie, Sadis Matalon, Jeannette E. Eagen, Stephen F. Doran, Israr Ahmad, Saurabh Aggarwal, Joo-Yeun Oh, Stephen Gu
Publikováno v:
Toxicol Lett
Phosgene (Carbonyl Chloride, COCl2) remains an important chemical intermediate in many industrial processes such as combustion of chlorinated hydrocarbons and synthesis of solvents (degreasers, cleaners). It is a sweet smelling gas, and therefore doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648e3c16fbcbf59687d17947011dc3dd
https://doi.org/10.1101/521724
https://doi.org/10.1101/521724
Autor:
Sadis Matalon, Namasivayam Ambalavanan, Weifeng Song, Zhihong Yu, Chad Steele, Stavros Garantziotis, Stephen F. Doran
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 309:L205-L210
Exposure to chlorine (Cl2) damages airway and alveolar epithelia resulting in acute lung injury and reactive airway hyperresponsiveness (AHR) to methacholine. However, little is known about the effect of preexisting respiratory disease on Cl2-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec19b454ce18d986952ed75b769e87a
https://doi.org/10.1152/ajplung.00159.2015
https://doi.org/10.1152/ajplung.00159.2015