Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Stephen F Madden"'
Autor:
Sandra Roche, Patricia Gaule, Deirdre Winrow, Nupur Mukherjee, Fiona O'Neill, Neil T Conlon, Justine Meiller, Denis M Collins, Alexandra Canonici, Mohammed Ibrahim Fawsi, Alejandra Estepa-Fernández, Stephen F Madden, John Crown, Norma O'Donovan, Alex J Eustace
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282512 (2023)
Triple Negative Breast Cancer (TNBC), a subtype of breast cancer, has fewer successful therapeutic therapies than other types of breast cancer. Insulin-like growth factor receptor 1 (IGF1R) and the Insulin receptor (IR) are associated with poor outco
Externí odkaz:
https://doaj.org/article/b9644b158fb94f80a2b68dadca1eef19
Autor:
Alex J Eustace, Neil T Conlon, Martina S J McDermott, Brigid C Browne, Patrick O’Leary, Frankie A Holmes, Virginia Espina, Lance A Liotta, Joyce O’Shaughnessy, Clair Gallagher, Lorraine O’Driscoll, Sweta Rani, Stephen F Madden, Neil A O’Brien, Charles Ginther, Dennis Slamon, Naomi Walsh, William M Gallagher, Radoslaw Zagozdzon, William R Watson, Norma O’Donovan, John Crown
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background Lapatinib has clinical efficacy in the treatment of trastuzumab-refractory HER2-positive breast cancer. However, a significant proportion of patients develop progressive disease due to acquired resistance to the drug. Induction of
Externí odkaz:
https://doaj.org/article/5de7181f330d45b98eeaa2bf7e64c819
Publikováno v:
Translational Oncology, Vol 46, Iss , Pp 102025- (2024)
New treatments are urgently required for triple-negative breast cancer (TNBC). As TP53 is mutated in approximately 80% of TNBC, it is theoretically an attractive target for new drugs for this disease. Arsenic trioxide (ATO), which is used to treat pr
Externí odkaz:
https://doaj.org/article/75039994030f4ff8baa64d4d87ad5977
Autor:
Radka Saldova, Helene Piccard, Marta Pérez-Garay, David J Harvey, Weston B Struwe, Marie C Galligan, Nele Berghmans, Stephen F Madden, Rosa Peracaula, Ghislain Opdenakker, Pauline M Rudd
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71159 (2013)
Ovarian cancer is the most lethal gynaecological cancer and is often diagnosed in late stage, often as the result of the unavailability of sufficiently sensitive biomarkers for early detection, tumour progression and tumour-associated inflammation. G
Externí odkaz:
https://doaj.org/article/eb35c5ff15784526a2bde178641a4006
Autor:
Pierce Geoghegan, Jennifer Clarke, Grace Hogan, Aoife Keogh, Hannah Marsh, Karen Donnelly, Natalie McEvoy, Aoife Doolan, Stephen F. Madden, Ignacio Martin‐Loeches, Michael Power, John G. Laffey, Gerard F. Curley
Publikováno v:
Physiological Reports, Vol 10, Iss 17, Pp n/a-n/a (2022)
Abstract Split ventilation (using a single ventilator to ventilate multiple patients) is technically feasible. However, connecting two patients with acute respiratory distress syndrome (ARDS) and differing lung mechanics to a single ventilator is con
Externí odkaz:
https://doaj.org/article/8af2340459a0475e9a04c2002b81338c
Autor:
Marie McIlroy, Leonie S. Young, Arnold D. Hill, Damir Varešlija, Fiona T. Bane, Sinead Toomey, Stephen F. Madden, Rachel Bleach, Laura Creevey
Gene changes in MCF7aro. The impact of cyp19 overexpression on SGK3 expression in an independent study. Impact of siRNA-AR/ER on SGK3 mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0250a342b809328bd2b15e92b1c58745
https://doi.org/10.1158/1535-7163.22509654.v1
https://doi.org/10.1158/1535-7163.22509654.v1
Autor:
Marie McIlroy, Leonie S. Young, Arnold D. Hill, Damir Varešlija, Fiona T. Bane, Sinead Toomey, Stephen F. Madden, Rachel Bleach, Laura Creevey
Supplemental tables 1& 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5564df5cb2f6f565158ac55a87b166
https://doi.org/10.1158/1535-7163.22509663.v1
https://doi.org/10.1158/1535-7163.22509663.v1
Autor:
Marie McIlroy, Leonie S. Young, Arnold D. Hill, Damir Varešlija, Fiona T. Bane, Sinead Toomey, Stephen F. Madden, Rachel Bleach, Laura Creevey
Impact of SiSGK3 in ZRaroLetR. MTS following siSGK3 under various hormonal stimuli.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b82e3960fce3404cb48d8b585214c6
https://doi.org/10.1158/1535-7163.22509648.v1
https://doi.org/10.1158/1535-7163.22509648.v1
Autor:
Marie McIlroy, Leonie S. Young, Arnold D. Hill, Damir Varešlija, Fiona T. Bane, Sinead Toomey, Stephen F. Madden, Rachel Bleach, Laura Creevey
Characterisation of ZR75aro-LetR. Validation of ER AR siRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576780111d5376c5844897a3afa655fa
https://doi.org/10.1158/1535-7163.22509657.v1
https://doi.org/10.1158/1535-7163.22509657.v1
Autor:
Marie McIlroy, Leonie S. Young, Arnold D. Hill, Damir Varešlija, Fiona T. Bane, Sinead Toomey, Stephen F. Madden, Rachel Bleach, Laura Creevey
Correlation between CYP19 amplification and SGK3 expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5187c66e3ec70c85a9c749caf82047
https://doi.org/10.1158/1535-7163.22509666
https://doi.org/10.1158/1535-7163.22509666