The Hepatic Compensatory Response to Elevated Systemic Sulfide Promotes Diabetes

Autor: Thierry Sulpice, Martin E. Barrios-Llerena, Matthew T G Gibbins, Ruma Banerjee, Thomas H. Gillingwater, Madara Brice, Gillian A. Gray, Huizhong Su, Nicholas M. Morton, Anne Tailleux, Subhankar Singha, Colin Selman, Peter L. Freddolino, Natalie Z.M. Homer, Clare Mc Fadden, Claire McMaster, Marouane Libiad, Kyo Han Ahn, Stephen E. Wilkie, François Briand, Roderick N. Carter, Victor Vitvitsky, Nourdine Faresse, Thierry Le Bihan, Bart Staels, Scott G. Denham, Barry Emerson, Richard C. Hartley, Andrew J. Finch

Publikováno v: Nicholas Carter, R, Gibbins, M T G, Barrios-Llerena, M E, Wilkie, S E, Freddolino, P L, Libiad, M, Vitvitsky, V, Emerson, B, Le Bihan, T, Brice, M, Su, H, Denham, S G, Homer, N Z M, McFadden, C, Tailleux, A, Faresse, N, Sulpice, T, Briand, F, Gillingwater, T H, Han Ahn, K, Singha, S, McMaster, C, Hartley, R C, Staels, B, Gray, G A, J Finch, A, Selman, C, Banerjee, R & Morton, N M 2021, ' The Hepatic Compensatory Response to Elevated Systemic Sulfide Promotes Diabetes ', Cell Reports . https://doi.org/10.1016/j.celrep.2021.109958
Cell Reports

Summary Impaired hepatic glucose and lipid metabolism are hallmarks of type 2 diabetes. Increased sulfide production or sulfide donor compounds may beneficially regulate hepatic metabolism. Disposal of sulfide through the sulfide oxidation pathway (S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc399f070262aaf17b48ed0cb1b2591
https://www.pure.ed.ac.uk/ws/files/239134274/CELL_REPORTS_D_21_00011_R3.pdf

Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice

Autor: James R. Mitchell, William A. Sands, Colin Selman, Diana E. Marcu, Nicholas M. Morton, Stephen E. Wilkie, Roderick N. Carter, Lorna Mulvey, Christopher Hine

Publikováno v: Wilkie, S E, Mulvey, L, Sands, W A, Marcu, D E, Carter, R N, Morton, N M, Hine, C, Mitchell, J R & Selman, C 2020, ' Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice ', GeroScience . https://doi.org/10.1007/s11357-020-00168-2
GeroScience
GeroScience, 42 (2)

Modulation of the ageing process by dietary restriction (DR) across multiple taxa is well established. While the exact mechanism through which DR acts remains elusive, the gasotransmitter hydrogen sulphide (H2S) may play an important role. We employe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dba5bdf54d7e44a512715151460aab
https://www.pure.ed.ac.uk/ws/files/150202707/Morton_N_Strain_specificity_....pdf