Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Stephen E. Maher"'
Autor:
Jae Hun Shin, Jaekwang Jeong, Jungmin Choi, Jaechul Lim, Ravi K. Dinesh, Jonathan Braverman, Jun Young Hong, Stephen E. Maher, Maria C. Amezcua Vesely, WonJu Kim, Ja-Hyun Koo, Wenwen Tang, Dianqing Wu, Holly N. Blackburn, Rosa M. Xicola, Xavier Llor, Omer Yilmaz, Je-Min Choi, Alfred L.M. Bothwell
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102411- (2021)
Summary: Enhanced stemness in colorectal cancer has been reported and it contributes to aggressive progression, but the underlying mechanisms remain unclear. Here we report a Wnt ligand, Dickkopf-2 (DKK2) is essential for developing colorectal cancer
Externí odkaz:
https://doaj.org/article/67458ed79ffd44e9bbd751bcc6f69111
Autor:
Alireza G. Senejani, Yanfeng Liu, Dawit Kidane, Stephen E. Maher, Caroline J. Zeiss, Hong-Jae Park, Michael Kashgarian, Jennifer M. McNiff, Daniel Zelterman, Alfred L.M. Bothwell, Joann B. Sweasy
Publikováno v:
Cell Reports, Vol 6, Iss 1, Pp 1-8 (2014)
A replication study of a previous genome-wide association study (GWAS) suggested that a SNP linked to the POLB gene is associated with systemic lupus erythematosus (SLE). This SNP is correlated with decreased expression of Pol β, a key enzyme in the
Externí odkaz:
https://doaj.org/article/d60217a0e3fe4edaa2240b7b757d30f8
Autor:
Jae Hun Shin, Jooyoung Park, Jaechul Lim, Jaekwang Jeong, Ravi K Dinesh, Stephen E Maher, Jeonghyun Kim, Soyeon Park, Jun Young Hong, John Wysolmerski, Jungmin Choi, Alfred LM Bothwell
Publikováno v:
eLife, Vol 13 (2024)
Metastasis is the leading cause of cancer-related mortality. Paneth cells provide stem cell niche factors in homeostatic conditions, but the underlying mechanisms of cancer stem cell niche development are unclear. Here, we report that Dickkopf-2 (DKK
Externí odkaz:
https://doaj.org/article/dffa8146f0424133a38409a5842a0105
Autor:
Bernadette Marquez-Nostra, Sandeep Mittal, Manali Phadke, Fangyong Li, Alfred L.M. Bothwell, Stephen E. Maher, Tim Mulnix, Michael Liu, Erika Belitzky, Sharon K. Michelhaugh, Tibor Keler, Jean-Dominique Gallezot, Alessandra Cavaliere, Supum Lee
There is a need for prognostic markers to select patients most likely to benefit from antibody–drug conjugate (ADC) therapy. We quantified the relationship between pretreatment PET imaging of glycoprotein nonmetastatic melanoma B (gpNMB) with 89Zr-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2012efa8df8a478df4247a589303e6
https://doi.org/10.1158/1535-7163.c.6543322.v1
https://doi.org/10.1158/1535-7163.c.6543322.v1
Autor:
Bernadette Marquez-Nostra, Sandeep Mittal, Manali Phadke, Fangyong Li, Alfred L.M. Bothwell, Stephen E. Maher, Tim Mulnix, Michael Liu, Erika Belitzky, Sharon K. Michelhaugh, Tibor Keler, Jean-Dominique Gallezot, Alessandra Cavaliere, Supum Lee
Supplementary Table from [89Zr]ZrDFO-CR011 PET Correlates with Response to Glycoprotein Nonmetastatic Melanoma B–targeted Therapy in Triple-negative Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803ec6b10e8366a6a87349cd081983fc
https://doi.org/10.1158/1535-7163.22522282.v1
https://doi.org/10.1158/1535-7163.22522282.v1
Autor:
Bernadette Marquez-Nostra, Sandeep Mittal, Manali Phadke, Fangyong Li, Alfred L.M. Bothwell, Stephen E. Maher, Tim Mulnix, Michael Liu, Erika Belitzky, Sharon K. Michelhaugh, Tibor Keler, Jean-Dominique Gallezot, Alessandra Cavaliere, Supum Lee
Supplementary Figure from [89Zr]ZrDFO-CR011 PET Correlates with Response to Glycoprotein Nonmetastatic Melanoma B–targeted Therapy in Triple-negative Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6bb32588ccbf3938a8bffcdd3db997
https://doi.org/10.1158/1535-7163.22522285
https://doi.org/10.1158/1535-7163.22522285
Autor:
Bernadette Marquez-Nostra, Sandeep Mittal, Manali Phadke, Fangyong Li, Alfred L.M. Bothwell, Stephen E. Maher, Tim Mulnix, Michael Liu, Erika Belitzky, Sharon K. Michelhaugh, Tibor Keler, Jean-Dominique Gallezot, Alessandra Cavaliere, Supum Lee
Supplementary Data from [89Zr]ZrDFO-CR011 PET Correlates with Response to Glycoprotein Nonmetastatic Melanoma B–targeted Therapy in Triple-negative Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a0c2ea43205e18b89e7e86281d711b
https://doi.org/10.1158/1535-7163.22522288.v1
https://doi.org/10.1158/1535-7163.22522288.v1
Autor:
Supum Lee, Alessandra Cavaliere, Jean-Dominique Gallezot, Tibor Keler, Sharon K. Michelhaugh, Erika Belitzky, Michael Liu, Tim Mulnix, Stephen E. Maher, Alfred L.M. Bothwell, Fangyong Li, Manali Phadke, Sandeep Mittal, Bernadette Marquez-Nostra
Publikováno v:
Molecular Cancer Therapeutics. 21:440-447
There is a need for prognostic markers to select patients most likely to benefit from antibody–drug conjugate (ADC) therapy. We quantified the relationship between pretreatment PET imaging of glycoprotein nonmetastatic melanoma B (gpNMB) with 89Zr-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd539708aea39b0de61dc9c9f341bb3b
https://doi.org/10.1158/1535-7163.mct-21-0590
https://doi.org/10.1158/1535-7163.mct-21-0590
Publikováno v:
Developmental Neurobiology. 81:389-399
Zika virus (ZIKV) can generate a number of neurological dysfunctions in infected humans. Here, we tested the potential of human immune cells to protect against ZIKV infection in genetically humanized MISTRG mice. FACS analysis showed robust reconstit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8efddc7f06742e61cc4c53e95867de
https://doi.org/10.1002/dneu.22820
https://doi.org/10.1002/dneu.22820
Autor:
Stephen E. Maher, Jaekwang Jeong, Jae Hun Shin, Alfred L. M. Bothwell, Jaechul Lim, Heon-Woo Lee
Publikováno v:
Proc Natl Acad Sci U S A
Cancer cells can develop an immunosuppressive tumor microenvironment to control tumor-infiltrating lymphocytes. The underlying mechanisms still remain unclear. Here, we report that mouse and human colon cancer cells acquire lymphocyte membrane protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbf33c96b2850186da8d677f62d5d6a
https://doi.org/10.1073/pnas.2110241118
https://doi.org/10.1073/pnas.2110241118