Výsledky vyhledávání - "Stephen E. Kendall"

Akademický článek

Autor: Joseph Najbauer, Peter C Huszthy, Michael E Barish, Elizabeth Garcia, Marianne Z Metz, Sarah M Myers, Margarita Gutova, Richard T Frank, Hrvoje Miletic, Stephen E Kendall, Carlotta A Glackin, Rolf Bjerkvig, Karen S Aboody

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35150 (2012)

BACKGROUND: Glioblastoma multiforme (GBM) is the most aggressive type of malignant primary brain tumors in adults. Molecular and genetic analysis has advanced our understanding of glioma biology, however mapping the cellular composition of the tumor

Externí odkaz: https://doaj.org/article/3189767300cc4139a0a12b54b1996e19

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Akademický článek

Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model.

Autor: Mya S Thu, Joseph Najbauer, Stephen E Kendall, Ira Harutyunyan, Nicole Sangalang, Margarita Gutova, Marianne Z Metz, Elizabeth Garcia, Richard T Frank, Seung U Kim, Rex A Moats, Karen S Aboody

Publikováno v: PLoS ONE, Vol 4, Iss 9, p e7218 (2009)

Treatment strategies for the highly invasive brain tumor, glioblastoma multiforme, require that cells which have invaded into the surrounding brain be specifically targeted. The inherent tumor-tropism of neural stem cells (NSCs) to primary and invasi

Externí odkaz: https://doaj.org/article/6e9c6530b27f450e81d5afb3fe211ad2

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Akademický článek

Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies.

Autor: Richard T Frank, Marissa Edmiston, Stephen E Kendall, Joseph Najbauer, Chia-Wei Cheung, Thewodros Kassa, Marianne Z Metz, Seung U Kim, Carlotta A Glackin, Anna M Wu, Paul J Yazaki, Karen S Aboody

Publikováno v: PLoS ONE, Vol 4, Iss 12, p e8314 (2009)

BACKGROUND: Recombinant monoclonal antibodies have emerged as important tools for cancer therapy. Despite the promise shown by antibody-based therapies, the large molecular size of antibodies limits their ability to efficiently penetrate solid tumors

Externí odkaz: https://doaj.org/article/3159f93b5aa04d759d7b2560ec324484

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Urokinase Plasminogen Activator and Urokinase Plasminogen Activator Receptor Mediate Human Stem Cell Tropism to Malignant Solid Tumors

Autor: Joseph Najbauer, Karen S. Aboody, Mark Guevorkian, Anna Gevorgyan, Donghong Zhao, Marianne Z. Metz, Seung U. Kim, Carlotta A. Glackin, Richard T. Frank, Margarita Gutova, Stephen E. Kendall, Marissa Edmiston

Publikováno v: Stem Cells. 26:1406-1413

Human neural and mesenchymal stem cells have been identified for cell-based therapies in regenerative medicine and as vehicles for delivering therapeutic agents to areas of injury and tumors. However, the signals required for homing and recruitment o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8c0ca251a01706a539f02625dfd3cc
https://doi.org/10.1634/stemcells.2008-0141

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Neural Stem Cell Targeting of Glioma Is Dependent on Phosphoinositide 3-Kinase Signaling

Autor: Michael E. Barish, Heather F. Johnston, Marianne Z. Metz, Elizabeth Garcia, Stephen E. Kendall, Carlotta A. Glackin, Karen S. Aboody, Joseph Najbauer, Marisa Bowers, Seung U. Kim, Shan Li

Publikováno v: Stem Cells. 26:1575-1586

The utility of neural stem cells (NSCs) has extended beyond regenerative medicine to targeted gene delivery, as NSCs possess an inherent tropism to solid tumors, including invasive gliomas. However, for optimal clinical implementation, an understandi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4a9d37f615decfc7bc6ec4f552306a
https://doi.org/10.1634/stemcells.2007-0887

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Bone Morphogenetic Protein 7 Protects Prostate Cancer Cells from Stress-Induced Apoptosis via Both Smad and c-Jun NH2-Terminal Kinase Pathways

Autor: Shangxin Yang, Minyoung Lim, A. Hari Reddi, Stephen E. Kendall, Linda K. Pham, Dario C. Altieri, Pradip Roy-Burman

Publikováno v: Cancer Research. 66:4285-4290

We reported earlier that exposure to exogenous bone morphogenetic protein 7 (BMP7) could strongly inhibit serum starvation–induced apoptosis to C4-2B cell line, a variant of the LNCaP human prostate cancer cell line with propensity for bone metasta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59957b6a55f491e67669e4ecb0781b1
https://doi.org/10.1158/0008-5472.can-05-4456

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Insulin acts as a myogenic differentiation signal for neural stem cells with multilineage differentiation potential

Autor: Daniel P. Moore, George N. Nikopoulos, Stephen Bellum, Calvin P.H. Vary, Joseph M. Verdi, Stephen E. Kendall, Chris J. Kubu, Rebecca A. Cowling, Mahmud Bani-Yaghoub

Publikováno v: Development. 131:4287-4298

Reports of non-neural differentiation of neural stem cells (NSCs) have been challenged by alternative explanations for expanded differentiation potentials. In an attempt to demonstrate the plasticity of NSC, neurospheres were generated from single re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923f147d6a867cd0c846f10a457b0cad
https://doi.org/10.1242/dev.01295

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Cellular Host Responses to Gliomas

Autor: Peter C. Huszthy, Joseph Najbauer, Marianne Z. Metz, Stephen E. Kendall, Richard T. Frank, Michael E. Barish, Elizabeth Garcia, Hrvoje Miletic, Rolf Bjerkvig, Karen S. Aboody, Sarah M. Myers, Margarita Gutova, Carlotta A. Glackin

Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 4, p e35150 (2012)

Background: Glioblastoma multiforme (GBM) is the most aggressive type of malignant primary brain tumors in adults. Molecular and genetic analysis has advanced our understanding of glioma biology, however mapping the cellular composition of the tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64476c3c6b5fb2272c742974c45b8d22
https://hdl.handle.net/1956/6479

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