Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Stephen E. Shanahan"'
Autor:
Stephen E. Shanahan, James D. Cuthbertson, Andrew L. Shannon-Little, Jan Saska, Valentin Magné, Ross M. Denton, Rhydian H. Beddoe, Keith G. Andrews, Helen F. Sneddon
Publikováno v:
Science. 365:910-914
Displacing OH groups catalytically The Mitsunobu reaction is widely used to invert the configuration of alcohols. However, its major drawback is the need to activate the alcohol with a full equivalent of phosphine, thereby generating a phosphine oxid
Autor:
Yunpeng Wang, Stephen E. Shanahan, Richard J. K. Taylor, Rebecca J. M. Goss, Danai S. Gkotsi, Jack A. Connolly, Hannes Ludewig, Jagwinder Dhaliwal, Matthew M. W. McLachlan, William P. Unsworth, James H. Naismith, Sunil V. Sharma
We thank the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007–2013/ERC grant agreement no. 614779 GenoChemetics to R.J.M.G.), Syngenta and Wellcome ISSF (grant no. 204821/Z/16/Z to D.S.G.) for generous fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1f06dd85e509dccd214f98051dc7ff
https://eprints.whiterose.ac.uk/152554/1/Revised_VirX1_210619_1_WPU_edit_AAM.docx
https://eprints.whiterose.ac.uk/152554/1/Revised_VirX1_210619_1_WPU_edit_AAM.docx
Autor:
Bridget V. Hogg, Barry Elsdon, Daniel P. Kloer, Timothy Robert Hawkes, Phillip J. Milnes, Shanaaz Tayab, Saranga Ranasinghe, Karine Lecoq, Matthew M. W. McLachlan, Richard Dale, John Martin Clough, Stephen E. Shanahan, Timothy J. C. O'Riordan, Karen D. Sumner, Anushka Howell
Publikováno v:
Pest Management Science. 72:2254-2272
BACKGROUND Exploiting novel herbicidal modes of action is an important method to overcome the challenges faced by increasing resistance and regulatory pressure on existing commercial herbicides. Recent reports of inhibitors of enzymes in the non-meva
Autor:
John M, Clough, Richard P, Dale, Barry, Elsdon, Timothy R, Hawkes, Bridget V, Hogg, Anushka, Howell, Daniel P, Kloer, Karine, Lecoq, Matthew Mw, McLachlan, Phillip J, Milnes, Timothy Jc, O'Riordan, Saranga, Ranasinghe, Stephen E, Shanahan, Karen D, Sumner, Shanaaz, Tayab
Publikováno v:
Pest management science. 72(12)
Exploiting novel herbicidal modes of action is an important method to overcome the challenges faced by increasing resistance and regulatory pressure on existing commercial herbicides. Recent reports of inhibitors of enzymes in the non-mevalonate path
Publikováno v:
Angewandte Chemie. 122:5706-5709
Autor:
Melanie Washington, Davina Humphreys, Lesley Nisbet, Philip Alan Skone, Royston C. B. Copley, Simon J. F. Macdonald, Graham G. A. Inglis, Richard J. Upton, Mike D. Barker, Margaret Clackers, Victoria Vinader, Haydn Terence Jones, Michael John Johnston, Iain M. McLay, Derek A. Demaine, Stephen E. Shanahan, David House, Richard Loiseau, Dan Tape, Michael V. Haase, Francois Pacquet, Iain Uings
Publikováno v:
Journal of Medicinal Chemistry. 49:4216-4231
The tetrahydronaphthalene-benzoxazine glucocorticoid receptor (GR) partial agonist 4b was optimized to produce potent full agonists of GR. Aromatic ring substitution of the tetrahydronaphthalene leads to weak GR antagonists. Discovery of an "agonist
Autor:
Alan Armstrong, Stephen E. Shanahan
Publikováno v:
Organic Letters. 7:1335-1338
[reaction: see text] The 7-azabicyclo[2.2.1]heptane ring system can be rapidly accessed from 5-(1-hydroxyallyl)-2-alkoxy-N-tosylpyrrolidines via an unusual aza-Prins-pinacol reaction mediated by Lewis acid. The products can undergo ring expansion to
Autor:
Richard S. Cooke, Alan Armstrong, Graham R. Cumming, Jamie D. Knight, Ian D. Edmonds, Stephen E. Shanahan
Publikováno v:
Chinese Journal of Chemistry. 23:1270-1272
Structure/reactivity relationships of N-alkoxycarbonyl- and N-carboxamidooxaziridines are explored, and conditions are discovered for the efficient amination of sulfides and primary amines. Reactions of these oxaziridines with alkenes are also examin
Publikováno v:
Angewandte Chemie (International ed. in English). 49(32)
Autor:
Martin N. Kenworthy, Richard J. K. Taylor, Alan R. Burns, Mahmood Ahmed, Stephen E. Shanahan, Christopher W. Barfoot, Michael G. Edwards
Publikováno v:
Organic letters. 10(2)
The first synthetic route to the tricyclic core of the dictyosphaeric acids has been established starting from readily available (S)-(−)-4-(tert-butyldimethylsilyloxy)cyclohexenone and involving 9 steps, including a ring-closing metathesis to produ