Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Stephen E Spurgeon"'
Autor:
Cody Paiva, J Claire Godbersen, Ryan S Soderquist, Taylor Rowland, Sumner Kilmarx, Stephen E Spurgeon, Jennifer R Brown, Sreesha P Srinivasa, Alexey V Danilov
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143685 (2015)
CDK (cyclin-dependent kinase) inhibitors have shown remarkable activity in CLL, where its efficacy has been linked to inhibition of the transcriptional CDKs (7 and 9) and deregulation of RNA polymerase and short-lived pro-survival proteins such as MC
Externí odkaz:
https://doaj.org/article/76cdc642921945679fd81474213b76e4
Autor:
Zoe L. Lyski, Myung Sun Kim, David Xthona Lee, David Sampson, Hans-Peter Raué, Vikram Raghunathan, Debbie Ryan, Amanda E. Brunton, Mark K. Slifka, William B. Messer, Stephen E. Spurgeon
Publikováno v:
Case Reports in Hematology, Vol 2022 (2022)
Individuals with chronic lymphocytic leukemia (CLL) have significant immune disfunction, often further disrupted by treatment. While currently available COVID-19 vaccinations are highly effective in immunocompetent individuals, they are often poorly
Externí odkaz:
https://doaj.org/article/b0a143a3e32d4a6fbe0d76b253bb0eb8
Autor:
Adam S. Kittai, Scott Best, Bria Thurlow, Vi Lam, Taylor Hashiguchi, Shaun Goodyear, Daniel O. Persky, Craig Okada, Byung Park, Stephen E. Spurgeon, Alexey V. Danilov
Publikováno v:
Haematologica, Vol 106, Iss 7 (2021)
Externí odkaz:
https://doaj.org/article/831868bb6ee24e4dad3f1c03097fdbda
Autor:
Prashasti Agrawal, Kevin A. David, Zhengming Chen, Suchitra Sundaram, Seo-Hyun Kim, Ryan Vaca, Yong Lin, Samuel Singer, Mary-Kate Malecek, Jordan Carter, Adam Zayac, Myung Sun Kim, Nishitha Reddy, Douglas Ney, Alma Habib, Christopher Strouse, Jerome Graber, Veronika Bachanova, Sidra Salman, Jean A. Vendiola, Nasheed Hossain, Mazie Tsang, Ajay Major, Maher K. Gandhi, Colm Keane, David A. Bond, Matthew Folstad, Julie Chang, Angel Mier-Hicks, Pallawi Torka, Priya Rajakumar, Parameswaran Venugopal, Stephanie Berg, Michael Glantz, Samuel A. Goldlust, Rahul Matnani, Pallavi Kumar, Thomas A. Ollila, Johnny Cai, Stephen E. Spurgeon, Alex G. Sieg, Joseph Cleveland, Narendranath Epperla, Reem Karmali, Seema Naik, Sonali M. Smith, James L. Rubenstein, Brad S. Kahl, Amy Chadburn, Andrew M. Evens, Peter Martin
Publikováno v:
Leukemia & Lymphoma. :1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecca343a2f4c867b072555e56d4ab883
https://doi.org/10.1080/10428194.2023.2191152
https://doi.org/10.1080/10428194.2023.2191152
Autor:
Michael L, Wang, Wojciech, Jurczak, Mats, Jerkeman, Judith, Trotman, Pier L, Zinzani, David, Belada, Carola, Boccomini, Ian W, Flinn, Pratyush, Giri, Andre, Goy, Paul A, Hamlin, Olivier, Hermine, José-Ángel, Hernández-Rivas, Xiaonan, Hong, Seok Jin, Kim, David, Lewis, Yuko, Mishima, Muhit, Özcan, Guilherme F, Perini, Christopher, Pocock, Yuqin, Song, Stephen E, Spurgeon, John M, Storring, Jan, Walewski, Jun, Zhu, Rui, Qin, Todd, Henninger, Sanjay, Deshpande, Angela, Howes, Steven, Le Gouill, Martin, Dreyling, Joseph C, Gardiner
Publikováno v:
New England Journal of Medicine. 386:2482-2494
Ibrutinib, a Bruton's tyrosine kinase inhibitor, may have clinical benefit when administered in combination with bendamustine and rituximab and followed by rituximab maintenance therapy in older patients with untreated mantle-cell lymphoma.We randoml
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc07bab8a2de65339706c4de97728d22
https://doi.org/10.1056/nejmoa2201817
https://doi.org/10.1056/nejmoa2201817
Autor:
Paul M. Barr, Stephen D. Smith, Mark J. Roschewski, Susan M. O’Brien, Jeff P. Sharman, Jason M. Melear, Priti Patel, Roser Calvo, Helen Yang, Stephen E. Spurgeon
Publikováno v:
Leukemia & Lymphoma. 63:1728-1732
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d9d02a6c9576008a6161e84609eb381
https://doi.org/10.1080/10428194.2022.2043301
https://doi.org/10.1080/10428194.2022.2043301
Autor:
Marc M. Loriaux, Brian J. Druker, Thomas O'Hare, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, Christian Michel Zwaan, Michael W. Deininger, Stephen T. Oh, Jason R. Gotlib, Tibor Kovacsovics, William H. Fleming, Stephen E. Spurgeon, Bill H. Chang, Jason M. Glover, Jade Bryant, Luke B. Fletcher, Guang Fan, Armand Bankhead, Wayne F. Yang, Jeffrey W. Tyner
PDF file - 2.3MB, (S1) Scheme for profiling leukemia patient samples with a panel of kinase inhibitors; (S2) Rank ordering of 151 sample IC50 values for each small-molecule kinase inhibitor; (S3) One-way clustering of leukemia patient sample response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358d61b91513d02b521b8ea73f316e28
https://doi.org/10.1158/0008-5472.22396950
https://doi.org/10.1158/0008-5472.22396950
Autor:
Marc M. Loriaux, Brian J. Druker, Thomas O'Hare, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, Christian Michel Zwaan, Michael W. Deininger, Stephen T. Oh, Jason R. Gotlib, Tibor Kovacsovics, William H. Fleming, Stephen E. Spurgeon, Bill H. Chang, Jason M. Glover, Jade Bryant, Luke B. Fletcher, Guang Fan, Armand Bankhead, Wayne F. Yang, Jeffrey W. Tyner
XLS file - 48K, Sources of Small-Molecule Kinase Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0413283c94e508f27580b33c39b2e7
https://doi.org/10.1158/0008-5472.22396923.v1
https://doi.org/10.1158/0008-5472.22396923.v1
Autor:
Marc M. Loriaux, Brian J. Druker, Thomas O'Hare, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, Christian Michel Zwaan, Michael W. Deininger, Stephen T. Oh, Jason R. Gotlib, Tibor Kovacsovics, William H. Fleming, Stephen E. Spurgeon, Bill H. Chang, Jason M. Glover, Jade Bryant, Luke B. Fletcher, Guang Fan, Armand Bankhead, Wayne F. Yang, Jeffrey W. Tyner
XLS file - 552K, 151 Patient Drug Curve Raw Data Points
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb94612032623b4a3cb5ba3e929bf3c9
https://doi.org/10.1158/0008-5472.22396935.v1
https://doi.org/10.1158/0008-5472.22396935.v1
Autor:
Marc M. Loriaux, Brian J. Druker, Thomas O'Hare, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, Christian Michel Zwaan, Michael W. Deininger, Stephen T. Oh, Jason R. Gotlib, Tibor Kovacsovics, William H. Fleming, Stephen E. Spurgeon, Bill H. Chang, Jason M. Glover, Jade Bryant, Luke B. Fletcher, Guang Fan, Armand Bankhead, Wayne F. Yang, Jeffrey W. Tyner
XLS file - 114K, Kinase Inhibitor Gene Targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4a89e6382912368a7b1439a3009483
https://doi.org/10.1158/0008-5472.22396944
https://doi.org/10.1158/0008-5472.22396944