Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Stephen E, Braun"'
Autor:
Giorgio Zenere, Chengxiang Wu, Cecily C Midkiff, Nathan M Johnson, Christopher P Grice, William C Wimley, Amitinder Kaur, Stephen E Braun
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0293990 (2024)
Chimeric antigen receptor (CAR)-T cells have demonstrated clinical potential, but current receptors still need improvements to be successful against chronic HIV infection. In this study, we address some requirements of CAR motifs for strong surface e
Externí odkaz:
https://doaj.org/article/e8dbe9a7e70048bfb98b004007c0f038
Autor:
Nathan M. Johnson, Anna Francesca Alvarado, Trey N. Moffatt, Joshua M. Edavettal, Tarun A. Swaminathan, Stephen E. Braun
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 451-465 (2021)
Three gene therapy strategies have received US Food and Drug Administration (FDA) approval; one includes HIV-1-based lentiviral vectors. These vectors incorporate features to provide long-term gene transfer and expression while minimizing generation
Externí odkaz:
https://doaj.org/article/b0ae2a92625d46128d7f5f921b0d27ac
Autor:
Amin Izadpanah, Fatemeh Daneshimehr, Kurtis Willingham, Zahra Barabadi, Stephen E. Braun, Aaron Dumont, Ricardo Mostany, Bysani Chandrasekar, Eckhard U. Alt, Reza Izadpanah
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Increased vascularization, also known as neoangiogenesis, plays a major role in many cancers, including glioblastoma multiforme (GBM), by contributing to their aggressive growth and metastasis. Although anti-angiogenic therapies provide some clinical
Externí odkaz:
https://doaj.org/article/cd9d8192a3634812bdd0769f0882f9bd
Autor:
Partha K. Chandra, Stephen E. Braun, Sudipa Maity, Jorge A. Castorena-Gonzalez, Hogyoung Kim, Jeffrey G. Shaffer, Sinisa Cikic, Ibolya Rutkai, Jia Fan, Jessie J. Guidry, David K. Worthylake, Chenzhong Li, Asim B. Abdel-Mageed, David W. Busija
Publikováno v:
Viruses, Vol 15, Iss 3, p 794 (2023)
Despite the suppression of human immunodeficiency virus (HIV) replication by combined antiretroviral therapy (cART), 50–60% of HIV-infected patients suffer from HIV-associated neurocognitive disorders (HAND). Studies are uncovering the role of extr
Externí odkaz:
https://doaj.org/article/229353644e9f4202a6485649497b10fd
Autor:
Stefan H. Scheller, Yasmine Rashad, Fayez M. Saleh, Kurtis A. Willingham, Antonia Reilich, Dong Lin, Reza Izadpanah, Eckhard U. Alt, Stephen E. Braun
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Transplanting HIV-1 positive patients with hematopoietic stem cells homozygous for a 32 bp deletion in the chemokine receptor type 5 (CCR5) gene resulted in a loss of detectable HIV-1, suggesting genetically disrupting CCR5 is a promising approach fo
Externí odkaz:
https://doaj.org/article/cdd5d9185f5b4533babba21b5503c30e
Autor:
Sharven Taghavi, Sarah Abdullah, Farhana Shaheen, Jacob Packer, Juan Duchesne, Stephen E. Braun, Chad Steele, Derek Pociask, Jay Kolls, Olan Jackson-Weaver
Publikováno v:
Shock.
Autor:
Kelli L. Jablon, Victoria L. Akerstrom, Min Li, Stephen E. Braun, Charles E. Norton, Jorge A. Castorena‐Gonzalez
Publikováno v:
Microcirculation (New York, N.Y. : 1994)REFERENCES.
To develop an experimental method for routine isolation and short-term culture of primary lymphatic endothelial cells from specific collecting vessels.Lymphatic endothelial cell tubes (LECTs) were isolated from micro-dissected collecting vessels. LEC
Autor:
Anna Francesca Alvarado, Nathan M. Johnson, Stephen E. Braun, Tarun A. Swaminathan, Joshua M. Edavettal, Trey N. Moffatt
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 451-465 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 451-465 (2021)
Three gene therapy strategies have received US Food and Drug Administration (FDA) approval; one includes HIV-1-based lentiviral vectors. These vectors incorporate features to provide long-term gene transfer and expression while minimizing generation
Autor:
Samantha L. Gerlach, Partha K. Chandra, Upal Roy, Sunithi Gunasekera, Ulf Göransson, William C. Wimley, Stephen E. Braun, Debasis Mondal
Publikováno v:
Medicines, Vol 6, Iss 1, p 33 (2019)
Background: Novel strategies to increase the efficacy of antiretroviral (ARV) drugs will be of crucial importance. We hypothesize that membranes of HIV-1-infected cells and enveloped HIV-1 particles may be preferentially targeted by the phytopeptide,
Externí odkaz:
https://doaj.org/article/de475b8bd4284e0eadbdb975ea2d7921
Autor:
Stefan H Scheller, Reza Izadpanah, Stephen E. Braun, Eckhard Alt, Dong Lin, Madeline M Robinson
Publikováno v:
The CRISPR Journal. 4:92-103
CCR5 is a coreceptor of human immunodeficiency virus type 1 (HIV-1). Transplantation of hematopoietic stem cells homozygous for a 32-bp deletion in CCR5 resulted in a loss of detectable HIV-1 in two patients, suggesting that genetic strategies to kno