Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stephen Dunaway"'
Autor:
Maria K Mateyak, Justyna K Pupek, Alexandra E Garino, McCllelan C Knapp, Sarah F Colmer, Terri Goss Kinzy, Stephen Dunaway
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190524 (2018)
In most eukaryotic organisms, translation elongation requires two highly conserved elongation factors eEF1A and eEF2. Fungal systems are unique in requiring a third factor, the eukaryotic Elongation Factor 3 (eEF3). For decades, eEF3, a ribosome-depe
Externí odkaz:
https://doaj.org/article/42ac79ade2dd45988516e906fcbd528e
Autor:
Domenica Paparatto, Dane Fletcher, Karen Piwowar, Kimberly Baldino, Charlotte Morel, Stephen Dunaway
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6181 (2009)
BACKGROUND:DNA damage checkpoints insure that the integrity of genomic DNA is faithfully maintained throughout the eukaryotic cell cycle. In the presence of damaged DNA, checkpoints are triggered to delay cell cycle progression to allow for DNA repai
Externí odkaz:
https://doaj.org/article/d45fdac82b0f4962817f497bdbe42187
Autor:
Sarah F. Colmer, Stephen Dunaway, Terri Goss Kinzy, Maria K. Mateyak, Alexandra E. Garino, Justyna K. Pupek, McCllelan C. Knapp
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190524 (2018)
PLoS ONE
PLoS ONE
In most eukaryotic organisms, translation elongation requires two highly conserved elongation factors eEF1A and eEF2. Fungal systems are unique in requiring a third factor, the eukaryotic Elongation Factor 3 (eEF3). For decades, eEF3, a ribosome-depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d89fa6297d2639741da2b35981e5352e
http://europepmc.org/articles/PMC5754060?pdf=render
http://europepmc.org/articles/PMC5754060?pdf=render
Publikováno v:
Evolution of the Protein Synthesis Machinery and Its Regulation ISBN: 9783319394671
Translation, the mechanism by which proteins are synthesized based on the information encoded in mRNA, is an essential process in all living organisms. Consisting of initiation, elongation and termination phases, many aspects of this process are cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd03a2f7c93489953020944300963853
https://doi.org/10.1007/978-3-319-39468-8_14
https://doi.org/10.1007/978-3-319-39468-8_14
Publikováno v:
Genes & Development. 20:3104-3116
The Saccharomyces cerevisiae DNA helicase Rrm3p is needed for normal fork progression through >1000 discrete sites scattered throughout the genome. Here we show that replication of all yeast chromosomes was markedly delayed in rrm3 cells. Delayed rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c59af6633a1f9ffbc4c5cd9adb5f2c
https://doi.org/10.1101/gad.1478906
https://doi.org/10.1101/gad.1478906
Autor:
James H. Wyche, John M. Sedivy, Panayotis Pantazis, Zhiyong Han, Kannan V. Balan, Paul Calabresi, Wenyi Wei, Stephen Dunaway, Eric A. Hendrickson, James W. Darnowski
Publikováno v:
Journal of Biological Chemistry. 277:17154-17160
Treatment of cells with the anti-cancer drug camptothecin (CPT) induces topoisomerase I (Top1)-mediated DNA damage, which in turn affects cell proliferation and survival. In this report, we demonstrate that treatment of the wild-type HCT116 (wt HCT11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615bf63a1fc924998379db42855a55ab
https://doi.org/10.1074/jbc.m112401200
https://doi.org/10.1074/jbc.m112401200
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e7ff2a87500bc59d21d7ec9ad6ed552
https://doi.org/10.1096/fasebj.26.1_supplement.550.5
https://doi.org/10.1096/fasebj.26.1_supplement.550.5
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e44700beae92766a375a37580c6ac991
https://doi.org/10.1096/fasebj.24.1_supplement.875.3
https://doi.org/10.1096/fasebj.24.1_supplement.875.3
Publikováno v:
Mitochondrion. 7(3)
Mitochondrial DNA (mtDNA) is highly susceptible to oxidative and chemically induced damage, and these insults lead to a number of diseases. In Saccharomyces cerevisiae, the DNA helicase Pif1p is localized to the nucleus and mitochondria. We show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a982cf0d9b3dbea80b298e376b72128
https://pubmed.ncbi.nlm.nih.gov/17257907
https://pubmed.ncbi.nlm.nih.gov/17257907
Publikováno v:
Journal of cell science. 118(Pt 1)
The protein kinase Chk1 is required for proper arrest of the cell cycle in response to DNA damage. We have previously shown in Schizosaccharomyces pombe, that upon DNA damage, phosphorylation of Chk1 correlates with checkpoint activation and that pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09eb6a225456d3cac1792208a726182
https://pubmed.ncbi.nlm.nih.gov/15585577
https://pubmed.ncbi.nlm.nih.gov/15585577