Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Stephen Dudley Holmes"'
Autor:
David J. Cutler, Shelagh Wilson, Ron A. Leslie, Sara Patel, Gareth Williams, Richard Morris, Robin E. Buckingham, Jonathan R.S. Arch, Vimal Sheridhar, Trevor A. Wattam, Martyn L. Evans, Stephen Dudley Holmes
Publikováno v:
Peptides. 20:1455-1470
The orexins are recently identified appetite-stimulating hypothalamic peptides. We used immunohistochemistry to map orexin-A and orexin-B immunoreactivity in rat brain, spinal cord, and some peripheral tissues. Orexin-A- and orexin-B-immunoreactive c
Autor:
Anne M. Romanic, Douglas W. P. Hay, Shelagh Wilson, Eliot H. Ohlstein, Nambi Aiyar, Calvert Louden, Wu-Schyong Liu, Henry M. Sarau, George I. Glover, Stephen A. Douglas, Stephen Dudley Holmes, Charles F. Sauermelch, Nabil Elshourbagy, Usman Shabon, John D. Martin, Robert W. Coatney, James J. Foley, Johathan K. Chambers, Derk J. Bergsma, Catherine E. Ellis, Dean E. McNulty, Robert S. Ames, John J. Trill, Zhaohui Ao, Robert N. Willette, Jeffrey M. Stadel, Jyoti Disa
Publikováno v:
Nature. 401:282-286
Urotensin-II (U-II) is a vasoactive ‘somatostatin-like’ cyclic peptide which was originally isolated from fish spinal cords1,2, and which has recently been cloned from man3. Here we describe the identification of an orphan human G-protein-coupled
Autor:
Diane L. McBay, Kamal A. Al-Barazanji, Jonathan R.S. Arch, Israel S. Gloger, Andrea C. Haynes, Mark T. McHale, Stephen Dudley Holmes, Danuta E. Mossakowska, Xin-Min Wang, Robin E. Buckingham
Publikováno v:
Obesity Research. 5:387-394
The obese Zucker rat (OZR) exhibits a missense mutation in the cDNA for the leptin receptor, producing a single amino acid substitution in the extracellular domain of the receptor. A mutation in the leptin receptor gene of the db/db mouse prevents th