Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Stephen Doran"'
Autor:
Ammar Saadoon Alishlash, Muna Sapkota, Israr Ahmad, Kelsey Maclin, Noor A. Ahmed, Adam Molyvdas, Stephen Doran, Carolyn J. Albert, Saurabh Aggarwal, David A. Ford, Namasivayam Ambalavanan, Tamas Jilling, Sadis Matalon
Publikováno v:
Redox Biology, Vol 44, Iss , Pp 102009- (2021)
Triggering factors of Acute Chest Syndrome (ACS) is a leading cause of death in patients with Sickle Cell Disease (SCD) and targeted therapies are limited. Chlorine (Cl2) inhalation happens frequently, but its role as a potential trigger of ACS has n
Externí odkaz:
https://doaj.org/article/1f8684c2049241cd8fbf6cab9177445c
Autor:
Muhammad Arif, Martina Klevstig, Rui Benfeitas, Stephen Doran, Hasan Turkez, Mathias Uhlén, Maryam Clausen, Johannes Wikström, Damla Etal, Cheng Zhang, Malin Levin, Adil Mardinoglu, Jan Boren
Publikováno v:
eLife, Vol 10 (2021)
Myocardial infarction (MI) promotes a range of systemic effects, many of which are unknown. Here, we investigated the alterations associated with MI progression in heart and other metabolically active tissues (liver, skeletal muscle, and adipose) in
Externí odkaz:
https://doaj.org/article/3773ce265234459eb41aa49c78f1ab73
Autor:
Dylan R. Addis, James A. Lambert, Changchun Ren, Stephen Doran, Saurabh Aggarwal, Tamas Jilling, Sadis Matalon
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 3 (2020)
Background Circulating levels of sFLT‐1 (soluble fms‐like tyrosine kinase 1), the extracellular domain of vascular endothelial growth factor (VEGF) receptor 1, and its ratio to levels of placental growth factor are markers of the occurrence and s
Externí odkaz:
https://doaj.org/article/968a9abd78b14417a8b572051aced012
Autor:
David A. Ford, Jaideep Honavar, Carolyn J. Albert, Mark A. Duerr, Joo Yeun Oh, Stephen Doran, Sadis Matalon, Rakesh P. Patel
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 8, Pp 1529-1540 (2016)
Exposure to chlorine (Cl2) gas can occur during accidents and intentional release scenarios. However, biomarkers that specifically indicate Cl2 exposure and Cl2-derived products that mediate postexposure toxicity remain unclear. We hypothesized that
Externí odkaz:
https://doaj.org/article/8c6e127d0cf44ff6ab687d02c62e9744
Autor:
Marion Laudette, Malin Lindbom, Muhammad Arif, Mathieu Cinato, Mario Ruiz, Stephen Doran, Azra Miljanovic, Mikael Rutberg, Linda Andersson, Martina Klevstig, Marcus Henricsson, Per-Olof Bergh, Entela Bollano, Nay Aung, J Gustav Smith, Marc Pilon, Tuulia Hyötyläinen, Matej Orešič, Rosie Perkins, Adil Mardinoglu, Malin C Levin, Jan Borén
Publikováno v:
Cardiovascular Research.
Aims Pro-protein convertase subtilisin-kexin type 9 (PCSK9), which is expressed mainly in the liver and at low levels in the heart, regulates cholesterol levels by directing low-density lipoprotein receptors to degradation. Studies to determine the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5eb0a7fcc766be0a9c73b76466754f6
https://doi.org/10.1093/cvr/cvad041
https://doi.org/10.1093/cvr/cvad041
Autor:
Stephen Doran, Per Fogelstrand, Martina Klevstig, Matias Ekstrand, Muhammad Arif, Martin Adiels, Adil Mardinoglu, Elmir Omerovic, Linda Andersson, Marion Laudette, Ismena Mardani, Malin Lindbom, Lisanna Sinisalu, Mathieu Cinato, Matej Orešič, Ara Koh, Malin Levin, Jan Borén, Åsa Tivesten, Anders Jeppsson, Richard L. Proia, Tuulia Hyötyläinen, Azra Miljanovic, Johannes Wikström, Entela Bollano, Max Levin, Marcus Henricsson, Martin O. Bergo, Karl Swärd
Publikováno v:
European Heart Journal
Aims Cardiac injury and remodelling are associated with the rearrangement of cardiac lipids. Glycosphingolipids are membrane lipids that are important for cellular structure and function, and cardiac dysfunction is a characteristic of rare monogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a36d884237089879869110aaf97b3a
https://doi.org/10.1093/eurheartj/ehab412
https://doi.org/10.1093/eurheartj/ehab412
Publikováno v:
Applied Health Economics and Health Policy. 19:133-140
The lidocaine 5% medicated plaster, Versatis®, has one therapeutic indication listed on the Summary of Product Characteristics—symptomatic relief of post-herpetic neuralgia (PHN) in adults. Increased expenditure on Versatis® suggests that there i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b47a5454468127f322a8f857952f3c30
https://doi.org/10.1007/s40258-020-00586-5
https://doi.org/10.1007/s40258-020-00586-5
Autor:
Hasan Turkez, Simon Lam, Jens Nielsen, Jan Borén, Hatice Hilal Yuksel, Adil Mardinoglu, Mathias Uhlén, Ozlem Altay, Stephen Doran
Publikováno v:
Briefings in Bioinformatics
The abnormalities in human metabolism have been implicated in the progression of several complex human diseases, including certain cancers. Hence, deciphering the underlying molecular mechanisms associated with metabolic reprogramming in a disease st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0991d250c333e624b21b646e1b5f550f
http://europepmc.org/articles/PMC7986590
http://europepmc.org/articles/PMC7986590
Publikováno v:
Pharmacoepidemiology and drug safetyREFERENCES. 30(8)
PURPOSE Significant increases in opioid utilisation have been reported in many countries in recent decades. This study investigated strong opioid prescribing in Irish General Medical Services (GMS) patients over a ten-year period. METHODS A retrospec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c772aa5db5b7a2c79836eb34bb6759
https://pubmed.ncbi.nlm.nih.gov/33840133
https://pubmed.ncbi.nlm.nih.gov/33840133
Autor:
Adil Mardinoglu, Jan Borén, Stephen Doran, Simon Lam, Muhammad Arif, Hasan Turkez, Mathias Uhlén, Abdulahad Bayraktar
Publikováno v:
Briefings in Bioinformatics
The development and progression of cardiovascular disease (CVD) can mainly be attributed to the narrowing of blood vessels caused by atherosclerosis and thrombosis, which induces organ damage that will result in end-organ dysfunction characterized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21aba24fce7df58906c8b02f42879426
http://europepmc.org/articles/PMC8425417
http://europepmc.org/articles/PMC8425417