Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stephen DeWall"'
Autor:
Minal Barve, Ahmad A Tarhini, Deepak Kilari, Randy Sweis, Timothy Yap, John Clark, Justin Gainor, Lu Gan, Ulka N Vaishampayan, Amna Sher, Yawen Ju, Susan Henry, Stephen DeWall, Asia McCune, Mo Qatanani
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/1c3b6e98b8f34fc1a8e666ad17762f46
Autor:
Tong-yuan Yang, Manuela Braun, Wibke Lembke, Fraser McBlane, John Kamerud, Stephen DeWall, Edit Tarcsa, Xiaodong Fang, Lena Hofer, Uma Kavita, Vijay V. Upreti, Swati Gupta, LiNa Loo, Alison J. Johnson, Rakesh Kantilal Chandode, Kay-Gunnar Stubenrauch, Maya Vinzing, Cindy Q. Xia, Vibha Jawa
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 471-494 (2022)
Immunogenicity has imposed a challenge to efficacy and safety evaluation of adeno-associated virus (AAV) vector-based gene therapies. Mild to severe adverse events observed in clinical development have been implicated with host immune responses again
Externí odkaz:
https://doaj.org/article/1b85bb2274f44631a3d3b829f5704b0f
Autor:
Timothy Yap, Justin Gainor, Meredith McKean, Melissa Johnson, Bruno Bockorny, Minal Barve, Randy Sweis, Ulka Vaishampayan, Ahmad Tarhini, Deepak Kilari, Yawen Ju, Si-Tuen Lee-Hoeflich, Stephen DeWall, Lan Liu, Nisha Shah, Ann Marie Kennedy, Lu Gan
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
H. A. Stirnadel-Farrant, Mary Birchler, R. Schroyer, Christine J. Watson, Oriol Bestard, Neil S. Sheerin, Stephen DeWall, John D. Scott, Stephen J. Wigmore, Lee Abberley, R. Noble, Ewen M Harrison, Menna R. Clatworthy, Robert B. Kirkpatrick, Luke Devey, M. Busz, David B. Kingsmore, Katrina Stevenson, S. Andrews, K. S. Thorneloe, E. Wlodek, Alexander N.R. Weber, D. Krull
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247972 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
Funder: GlaxoSmithKline; funder-id: http://dx.doi.org/10.13039/100004330
Introduction: Delayed graft function (DGF) following renal transplantation is a manifestation of acute kidney injury (AKI) leading to poor long-term outcome. Current treatm
Introduction: Delayed graft function (DGF) following renal transplantation is a manifestation of acute kidney injury (AKI) leading to poor long-term outcome. Current treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57954ffe765b43ecca9f79d4d6a549f6
Autor:
Stephen DeWall, Sara Brett, Keguan Chen, Andrew Gehman, George R Gunn, Ann M. Schwartz, Karen Liao
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0249049 (2021)
PLoS ONE, Vol 16, Iss 3, p e0249049 (2021)
Interleukin-7 (IL-7) signaling modulates T cell activity and is implicated in numerous autoimmune diseases. An anti-IL-7 receptor monoclonal antibody (GSK2618960) biotherapeutic was evaluated in healthy subjects for safety, pharmacokinetics (PK), pha
Autor:
Francesco Morena, Serena Acquati, Chiara Argentati, Sabata Martino, Stephen DeWall, Fiona Kelly, Stefano Zancan, Alessandra Biffi, Valeria Calbi, Alessandro Aiuti, Francesca Fumagalli
Publikováno v:
The journal of applied laboratory medicine. 6(2)
Background Cerebrospinal fluid (CSF) has emerged as a sensitive matrix for the screening of biomarkers for diagnosis and clinical follow-up of diseases with neurological manifestations, including some lysosomal storage disorders. In this study, we as
Publikováno v:
The AAPS Journal. 22
The objective of this manuscript is to provide the reader with two examples on how to present an immunogenicity risk assessment for a PEGylated therapeutic as part of Investigational New Drug (IND) application or during other stages of the drug devel
Autor:
Stephen DeWall, Karen E. Morrison, Alain Destée, Andrea Calvo, Annelot M. Dekker, Francesca Barbieri, Philip Van Damme, James D. Berry, Robert D. Henderson, Claude Desnuelle, Johannes Dorst, Linda O. Nichols, Jerzy Daniluk, Sonja Koerner, Adriano Chiò, Kristiana Salmon, Pierre-François Pradat, Albert C. Ludolph, Genevieve Matte, Harutoshi Fujimura, Gaëlle Bruneteau, Stewart Bates, Giuseppe Fuda, Torsten Grehl, Usha Gungabissoon, Andrea Sylvia Winkler, Byung Jo Kim, Eleanor Ramsey, Christen Shoesmith, Peggy Ho, Matthew C. Kiernan, Rodrigo Refoios Camejo, Saiju Jacob, Rob Stubbs, Thomas M. Ringer, Jonathan Bullman, Stephan A Botez, Michael A. van Es, Xenia Kobeleva, Stefano Milleri, Wim Robberecht, William Huynh, Mary Lou Watson, Mieko Ogino, Seung Hyun Kim, Chris Parkinson, Diane Boswell, Stephen J. Kolb, Jeremy M. Shefner, Katja Kollewe, Jane R. Temple, Paul Rees, Julian Grosskreutz, Deven Chauhan, K. Nishiyama, Leonard H. van den Berg, Marloes Stam, Susanne Petri, Rami Massie, Darryl Menezes, Tino Prell, Anthony Lynch, Raul Juntas-Morales, Andreas Funke, P. Nigel Leigh, Lawrence Korngut, Angela Genge, Cathy Alsop, Margie C. Zoing, Arseniy Lavrov, Rajat Mohindra, Anne E. Visser, Susanne Abdulla, Veronique Danel-Brunaud, William Camu, Matt Davies, Amy Lee, Erik Steinberg, Lorne Zinman, Jeffrey Price, Marie Helene Soriani, Matthew S Devine, Vincent Meininger, Géraldine Lautrette, Herman Sullivan
Publikováno v:
Lancet Neurology, 16(3), 208. Lancet Publishing Group
The Lancet Neurology
The Lancet Neurology, Elsevier, 2017, 16 (3), pp.208-216. ⟨10.1016/S1474-4422(16)30399-4⟩
The Lancet Neurology
The Lancet Neurology, Elsevier, 2017, 16 (3), pp.208-216. ⟨10.1016/S1474-4422(16)30399-4⟩
Summary Background Neurite outgrowth inhibitor A (Nogo-A) is thought to have a role in the pathophysiology of amyotrophic lateral sclerosis (ALS). A monoclonal antibody against Nogo-A showed a positive effect in the SOD1 G93A mouse model of ALS, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84786f0743df2f63aa43471c398c75f9
https://dspace.library.uu.nl/handle/1874/348903
https://dspace.library.uu.nl/handle/1874/348903
Autor:
Veronica Liu, Stephen DeWall, Joanna Opalinska, Josh Albert, Elisha J. Dettman, Boyenoh Gaye, Ruth M Barnard, Mary Birchler, Yan Deghenhardt, Zangdong He, Fabio Rigat
Publikováno v:
Blood. 132:1977-1977
Introduction: B-cell maturation antigen (BCMA) is a cell surface receptor that is widely expressed on multiple myeloma (MM) cells. GSK2857916 is a humanized Fc enhanced IgG1 anti-BCMA antibody conjugated to the microtubule inhibitor monomethyl aurist
Autor:
Catherine Wang, Thomas N. Lee, Daniel Sikkema, Jerry G. Page, Keguan Chen, Ann M. Schwartz, Stephen DeWall
Publikováno v:
Journal of Immunological Methods. 394:22-31
An electrochemiluminescent (ECL) bridging assay to detect anti-ofatumumab antibodies (ADA) in human serum samples was developed and validated. Using this assay format, clinical samples were first screened to identify potential ADA positive samples, w