Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stephen D. Yanofsky"'
Autor:
Jay E. Wrobel, Brian J. Arey, Stephen D. Yanofsky, Francisco J. López, M. Claudia Perez, Ariamala Gopalsamy, Christopher P. Holmes, Panayiotis E. Stevis, Richard C. Winneker
Publikováno v:
Biochemical and biophysical research communications. 368(3)
The follicle-stimulating hormone is critical to reproductive success and is an important target for development of novel reproductive therapies. We have recently reported the development of thiazolidinone positive allosteric modulators of the follicl
Autor:
Stephen D. Yanofsky, Gerard Zurawski
Publikováno v:
Journal of Biological Chemistry. 265:13000-13006
Two mutational approaches were used to perform a thorough structure-function analysis of the first 53 residues of the 159-residue cytokine human interleukin-1 alpha (hIL-1 alpha). In this study, a total of 26 deletions, 97 multiple amino acid substit
Autor:
Erik A. Whitehorn, Ronald W. Barrett, Barbara Aguilar, Christopher P. Holmes, Richard C. Winneker, May M. Wu, Derek Maclean, Randall A. Scheuerman, Emily S. Shen, Donald E. Frail, Emily Tate, Francisco J. López, Frank Holden, Stephen D. Yanofsky, Brian J. Arey
Publikováno v:
The Journal of biological chemistry. 281(19)
The pituitary glycoprotein hormones, luteinizing hormone and follicle-stimulating hormone (FSH), act through their cognate receptors to initiate a series of coordinated physiological events that results in germ cell maturation. Given the importance o
Publikováno v:
High Throughput Screening for Novel Anti-Inflammatories ISBN: 9783034895781
Interleukin 1 (IL-1) is a pivotal pro-inflammatory cytokine involved in many types of inflammatory and autoimmune diseases [1]. IL-1 production whether initiated by infection or host antigen, initiates an inflammatory cascade which includes the induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8421c712f4fc9721ff1c972de3c55f
https://doi.org/10.1007/978-3-0348-8462-4_11
https://doi.org/10.1007/978-3-0348-8462-4_11
Autor:
Edoardo Sarubbi, Ann L. Akeson, Susanne Trump-Kallmeyer, Stephen D. Yanofsky, Ronald W. Barrett, H.A. Schreuder, Adolfo Soffientini, Chantal Tardif, Terry L. Bowlin
Publikováno v:
Nature. 386(6621)
Inflammation, regardless of whether it is provoked by infection or by tissue damage, starts with the activation of macrophages which initiate a cascade of inflammatory responses by producing the cytokines interleukin-1 (IL-1) and tumour necrosis fact
Publikováno v:
Nature. 259:60-63
THE chromosome of bacteriophage ϕ29, one of the smallest Bacillus phages, is a non-permuted linear duplex DNA molecule of molecular weight 11 × 106 (refs 1 and 2) that seems to be circularised by association with a protein, as circular monomers are
Autor:
Herbert W. Boyer, Judith A. McClarin, Patricia J. Greene, Stephen D. Yanofsky, Robert Love, John M. Rosenberg
Publikováno v:
Proteins. 2(4)
EcoRI endonuclease mutants were isolated in a methylase-deficient background following in vitro hydroxylamine mutagenesis of plasmid pKG2 (Kuhn et al.: Gene 44:253-263, 1986). Mutants which survived high-level endonuclease expression (IPTG induction)