Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephen D. Thorp"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 24, Iss , Pp 661-671 (2024)
The influence of biomechanics on cell function has become increasingly defined over recent years. Biomechanical changes are known to affect oncogenesis; however, these effects are not yet fully understood. Atomic force microscopy (AFM) is the gold st
Externí odkaz:
https://doaj.org/article/3ddc98631da143d798e2c9ca3a4130de
Publikováno v:
Interact Cardiovasc Thorac Surg
OBJECTIVES The Magna Ease aortic valve (Edwards Lifesciences, Irvine, CA) is a third-generation bioprosthetic valve developed as a modification of the well-studied Perimount and Magna valve designs. This study’s objective is to evaluate a large, si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2567012f44985b09ebf4d683ab14945
https://doi.org/10.1093/icvts/ivab016
https://doi.org/10.1093/icvts/ivab016
Geotemporal Fluorophore Biodistribution Mapping of Colorectal Cancer: Micro and Macroscopic Insights
Autor:
Niall P. Hardy, Niall Mulligan, Jeffrey Dalli, Jonathan P. Epperlein, Peter M. Neary, William Robertson, Richard Liddy, Stephen D. Thorpe, John J. Aird, Ronan A. Cahill
Publikováno v:
Current Oncology, Vol 31, Iss 2, Pp 849-861 (2024)
Fluorescence-guided oncology promises to improve both the detection and treatment of malignancy. We sought to investigate the temporal distribution of indocyanine green (ICG), an exogenous fluorophore in human colorectal cancer. This analysis aims to
Externí odkaz:
https://doaj.org/article/ccc433db910e4c4692c800b281a74d42
Autor:
Gaby A. Iskander, Alan T. Davis, Nicholas S Adams, Laura Krech, Alistair J. Chapman, Gerald Paul Wright, Stephen D. Thorp, Carlos H. Rodriguez, Julie Le, Charles J. Gibson
Publikováno v:
Journal of safety research. 75
Introduction: Motorcycles are colloquially referred to as “donorcycles” among medical staff. However, the actual impact of helmet laws and helmet use on organ donation is unknown. Michigan’s 35-year-old universal helmet law (UHL) was repealed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c312c8305cb60576487811cb00c5625
https://pubmed.ncbi.nlm.nih.gov/33334475
https://pubmed.ncbi.nlm.nih.gov/33334475
Autor:
Carlos Matellan, Dariusz Lachowski, Ernesto Cortes, Kai Ning Chiam, Aleksandar Krstic, Stephen D. Thorpe, Armando E. del Río Hernández
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-11 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is the most common and lethal form of pancreatic cancer, characterised by stromal remodelling, elevated matrix stiffness and high metastatic rate. Retinoids, compounds derived from vitamin A, have a hi
Externí odkaz:
https://doaj.org/article/2566f2763fe74c66a28b1cdb8c6ec4bf
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
This study examined the role of sirtuins in the regenerative potential of articular chondrocytes. Sirtuins (SIRT1-7) play a key role in regulating cartilage homeostasis. By inhibiting pro-inflammatory pathways responsible for cartilage degradation an
Externí odkaz:
https://doaj.org/article/1f8abf52476c450fad6b15c49082e7d8
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Pluripotent cells are subject to much interest as a source of differentiated cellular material for research models, regenerative medical therapies and novel applications such as lab-cultured meat. Greater understanding of the pluripotent state and co
Externí odkaz:
https://doaj.org/article/543a4a22520040b38663fe9256aa2222
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/f6c7c46be7ef4ecfbd37a128ed3ce39f
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Organ-on-chip (OOC) systems recapitulate key biological processes and responses in vitro exhibited by cells, tissues, and organs in vivo. Accordingly, these models of both health and disease hold great promise for improving fundamental research, drug
Externí odkaz:
https://doaj.org/article/0ec38aad05f64e0093bd6c4e9eb2081a
Autor:
Dariusz Lachowski, Ernesto Cortes, Carlos Matellan, Alistair Rice, David A. Lee, Stephen D. Thorpe, Armando E. del Río Hernández
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mechanical forces regulate cell functions through multiple pathways. G protein-coupled estrogen receptor (GPER) is a seven-transmembrane receptor that is ubiquitously expressed across tissues and mediates the acute cellular response to estrogens. Her
Externí odkaz:
https://doaj.org/article/8153b8e6157e4fde885521f46a3fcb2a