Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephen D. Lupton"'
Autor:
Stephen D. Lupton, Lawrence S. Evans, Stanley R. Riddell, Andrew L. Feldhaus, Philip D. Greenberg, Brad H. Nelson, Pamela R. Witte, Lori A. Jones
Publikováno v:
Human Gene Therapy. 10:1941-1951
Adoptive immunotherapy with ex vivo-expanded antigen-specific cytotoxic T lymphocytes (CTLs) has been shown to clear viral infections and eliminate tumors in murine models. Clinical trials have also reported promising data for the use of adoptive imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427f15f572130f0f3a1d3b77ece97bf7
https://doi.org/10.1089/10430349950017301
https://doi.org/10.1089/10430349950017301
Autor:
Stanley R. Riddell, Mark Gilbert, Deborah A. Lewinsohn, Philip D. Greenberg, Robert W. Overell, Sara A. Manley, Stephen D. Lupton, Thomas C. Reynolds, Mark Elliott, Linda Wilson, Lawrence Corey
Publikováno v:
Nature Medicine. 2:216-223
The introduction and expression of genes in somatic cells is an innovative therapy for correcting genetic deficiency diseases and augmenting immune function. A potential obstacle to gene therapy is the elimination of such gene-modified cells by an im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f34189410382a0bab78ca6700fdb624
https://doi.org/10.1038/nm0296-216
https://doi.org/10.1038/nm0296-216
Autor:
S. Scheeler, Robert W. Overell, Stephen D. Lupton, Stanley R. Riddell, Philip D. Greenberg, Jan M. Agosti, Mark J. Gilbert, T. P. Loughran, Lawrence Corey, Robert W. Coombs
Publikováno v:
Human Gene Therapy. 3:319-338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601ad8069193df6e31a2532fd5b42a5c
https://doi.org/10.1089/hum.1992.3.3-319
https://doi.org/10.1089/hum.1992.3.3-319
Autor:
C.I. Brannan, Stephen D. Lupton, Nancy A. Jenkins, C E Grubin, J M Wignall, B. Mosley, J.L. Slack, David Cosman, L.L. Brunton, Catherine J. McMahan
Publikováno v:
The EMBO Journal. 10:2821-2832
cDNA clones corresponding to an Mr approximately 80,000 receptor (type I receptor) for interleukin-1 (IL-1) have been isolated previously by mammalian expression. Here, we report the use of an improved expression cloning method to isolate human and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db67a034b347d529c7b2f505da61c662
https://doi.org/10.1002/j.1460-2075.1991.tb07831.x
https://doi.org/10.1002/j.1460-2075.1991.tb07831.x
Publikováno v:
Molecular and Cellular Biology. 11:3374-3378
The hygromycin phosphotransferase gene was fused in-frame with the herpes simplex virus type 1 thymidine kinase gene. The resulting fusion gene (termed HyTK) confers hygromycin B resistance for dominant positive selection and ganciclovir sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e97f931f16510e8314b7849e8dcecc
https://doi.org/10.1128/mcb.11.6.3374-3378.1991
https://doi.org/10.1128/mcb.11.6.3374-3378.1991
Autor:
Piero Musiani, Maria Ferrantini, Massimo Venditti, Andrea Modesti, Lucia Gabriele, Alessandro Modica, Laura Santodonato, Filippo Belardelli, Enrico Proietti, Stephen D. Lupton
Publikováno v:
Scopus-Elsevier
Transduction of the murine interferon-alpha (IFN-alpha) gene into various malignant mouse tumor cells has resulted in the loss of tumorigenicity and an acquired capacity to induce long-lasting antitumor immunity following their injection into immunoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3f2a3441e12db88a8d8b953f638f18
http://hdl.handle.net/11573/419000
http://hdl.handle.net/11573/419000
Publikováno v:
Human gene therapy. 6(12)
The herpes simplex virus thymidine kinase (HSV-TK) converts ganciclovir (GCV) into a toxic product and allows selective elimination of TK+ cells in vitro and in vivo. It is currently being used in clinical gene therapy trials as a therapeutic gene or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf297938aa3d47eb6e2c9f2bb07f43d3
https://pubmed.ncbi.nlm.nih.gov/8664377
https://pubmed.ncbi.nlm.nih.gov/8664377
Autor:
Raymond G. Goodwin, Kathryn Hjerrild, Rita Jerzy, David Cosman, Anthony E. Namen, William Clevenger, Stephen D. Lupton, Steve Gillis, Ann E. Schmierer
Publikováno v:
Proceedings of the National Academy of Sciences. 86:302-306
A cDNA encoding biologically active human interleukin 7 was isolated by hybridization with the homologous murine clone. Nucleotide sequence analysis indicated that this cDNA was capable of encoding a protein of 177 amino acids with a signal sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22455c7832d53f9ca99638e005aad7e
https://doi.org/10.1073/pnas.86.1.302
https://doi.org/10.1073/pnas.86.1.302
Autor:
Carl J. March, Stephen D. Lupton, Diane Y. Mochizuki, Raymond G. Goodwin, Anthony E. Namen, Kathryn A. Hjerrild, Ann E. Schmierer, Steven Gillis, Janis M. Wignall, Bruce Mosley, David L. Urdal, David Cosman
Publikováno v:
Nature. 333(6173)
The events involved in the commitment and development of lymphoid lineage cells are poorly understood. We have used a recently described long-term culture system1 to establish a bioassay that can detect a novel growth factor capable of stimulating th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c26f482b29b07d638621e949bf48eb
https://pubmed.ncbi.nlm.nih.gov/3259677
https://pubmed.ncbi.nlm.nih.gov/3259677