Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephen D. Kozuch"'
Autor:
Christopher N. Cultrara, Stephen D. Kozuch, Poornema Ramasundaram, Claudia J. Heller, Sunil Shah, Adah E. Beck, David Sabatino, Jenny Zilberberg
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background Glucose regulated protein 78 (GRP78) is a resident chaperone of the endoplasmic reticulum and a master regulator of the unfolded protein response under physiological and pathological cell stress conditions. GRP78 is overexpressed
Externí odkaz:
https://doaj.org/article/a378f8276edd4592be7f64ca65544a05
Autor:
Stephen D. Kozuch, Christopher N. Cultrara, Adah E. Beck, Claudia J. Heller, Sunil Shah, Mayurbhai R. Patel, Jenny Zilberberg, David Sabatino
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 12975-12984 (2018)
Externí odkaz:
https://doaj.org/article/f4e7be1661b4441693a2d3d5b16cd203
Autor:
Sunil Shah, David Sabatino, Christopher N. Cultrara, Adah E. Beck, Stephen D. Kozuch, Jenny Zilberberg, Poornema Ramasundaram, Claudia J. Heller
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-14 (2018)
BMC Cancer
BMC Cancer
Background Glucose regulated protein 78 (GRP78) is a resident chaperone of the endoplasmic reticulum and a master regulator of the unfolded protein response under physiological and pathological cell stress conditions. GRP78 is overexpressed in many c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2485c577e4b9ac6b6f3df21fbdcb549c
http://link.springer.com/article/10.1186/s12885-018-5178-8
http://link.springer.com/article/10.1186/s12885-018-5178-8
Autor:
Steven Park, Mengyan Li, Zain Siddiqui, Wanyi Fu, Stephen D. Kozuch, Peter K. Nguyen, David S. Perlin, Patricia Iglesias-Montoro, Biplab Sarkar, Reshma Paul, Jagannath Mondal, Shivani Jaisinghani, Wen Zhang, David Sabatino, Namita Dube, Daiyong Deng, Vivek A. Kumar
Publikováno v:
ACS biomaterials scienceengineering. 5(9)
Self-assembled peptide nanofibers can form biomimetic hydrogels at physiological pH and ionic strength through noncovalent and reversible interactions. Inspired by natural antimicrobial peptides, we designed a class of cationic amphiphilic self-assem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e027d257a3f954b9c6ffaeb241366a82
https://pubmed.ncbi.nlm.nih.gov/33448838
https://pubmed.ncbi.nlm.nih.gov/33448838
Autor:
Christopher N. Cultrara, Adah E. Beck, Claudia J. Heller, Mayurbhai R. Patel, Sunil Shah, Jenny Zilberberg, David Sabatino, Stephen D. Kozuch
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 12975-12984 (2018)
ACS Omega
ACS Omega
The integration of therapy and diagnostics, termed "theranostics", has recently gained widespread utility in the development of new and improved therapeutics that effectively diagnose and treat diseases, such as cancer. In this study, the covalent at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ab22010003314457e5b05294420316
https://doaj.org/article/f4e7be1661b4441693a2d3d5b16cd203
https://doaj.org/article/f4e7be1661b4441693a2d3d5b16cd203
Publikováno v:
Chemical biologydrug design. 93(6)
New methods for the synthesis of higher-order siRNA motifs and their bioconjugates have recently gained widespread attention in the development of new and improved gene therapeutics. Our efforts aim to produce new chemical tools and protocols for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f4f21769647fe775f4ee2fb5c62796
https://pubmed.ncbi.nlm.nih.gov/30480355
https://pubmed.ncbi.nlm.nih.gov/30480355
Autor:
Gabriela Chiosis, Stephen D. Kozuch, John Koren, Suiying Huang, Reeta Yadav, Christopher N. Cultrara, Uri Samuni, Mayurbhai R. Patel, David Sabatino
Publikováno v:
Nano letters. 16(10)
The emerging field of RNA nanotechnology has been used to design well-programmed, self-assembled nanostructures for applications in chemistry, biology, and medicine. At the forefront of its utility in cancer is the unrestricted ability to self-assemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62a7948359b5cd56f7c541e48b8110e
https://pubmed.ncbi.nlm.nih.gov/27669096
https://pubmed.ncbi.nlm.nih.gov/27669096
Publikováno v:
ChemInform. 47
Nucleoside- and nucleotide-based chemotherapeutics have been used to treat cancer for more than 50 years. However, their inherent cytotoxicities and the emergent resistance of tumors against treatment has inspired a new wave of compounds in which the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5438ade45d288e8ef4ea4e971833b5d
https://doi.org/10.1002/chin.201612284
https://doi.org/10.1002/chin.201612284
Publikováno v:
ChemMedChem. 11(3)
Nucleoside- and nucleotide-based chemotherapeutics have been used to treat cancer for more than 50 years. However, their inherent cytotoxicities and the emergent resistance of tumors against treatment has inspired a new wave of compounds in which the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f9cd19f5013403b782dec788f3bc5c
https://pubmed.ncbi.nlm.nih.gov/26663095
https://pubmed.ncbi.nlm.nih.gov/26663095
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e83421 (2013)
PLoS ONE, Vol 8, Iss 12, p e83421 (2013)
Protein conformational changes are commonly associated with the formation of protein complexes. The non-catalytic death effector domains (DEDs) mediate protein-protein interactions in a variety of cellular processes, including apoptosis, proliferatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f88e072dbcbcf5e2997c26eb69a5f6
https://doi.org/10.1371/journal.pone.0083421
https://doi.org/10.1371/journal.pone.0083421