Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stephen D. Hodges"'
Autor:
Floyd F. Snyder, Stephen D. Hodges
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 23:1269-1274
A media has been developed which enables the assessment of mitochondrial function in fibroblasts by measuring proliferation as an end point.
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 27(6)
A metabolomic analysis of plasma amino acids and acylcarnitines was applied to four disorders of nucleotide metabolism. Multivariate analysis gave score plots that show segregation of hypoxanthine phosphoribosyltransferase and adenine phosphoribosylt
Publikováno v:
Purine and Pyrimidine Metabolism in Man VIII ISBN: 9781461361053
IMP dehydrogenase is recognized as a rate limiting step in the de novo synthesis of guanine nucleotides and is a target for chemotherapeutic intervention. We selected a mouse neuroblastoma (NB) cell line capable of growth in 1 mM mycophenolic acid (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b5d8ee753ee40a7b0f96a4ac9493130
https://doi.org/10.1007/978-1-4615-2584-4_151
https://doi.org/10.1007/978-1-4615-2584-4_151
Publikováno v:
Veterinary pathology. 30(2)
β-mannosidosis is a recently recognized lysosomal storage disease in newborn Salers calves. Fourteen calves with β-mannosidase deficiency were examined. Twelve calves were from routine laboratory submissions, and two calves were the result of a bre
Publikováno v:
Biochemical and biophysical research communications. 173(2)
A fatal inherited glycoprotein storage disorder is described in Salers cattle which affects both sexes. Affected calves are unable to stand at birth, have a marked intention tremor, markedly enlarged kidneys, decreased white matter in all areas of th
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 173(2)
Interleukin-2-dependent T cell lines can be started from as little as 1 ml of peripheral blood and expanded to 50 x 10(6) cells within 12 days. These cells represent an easily obtainable source of nucleated tissue with certain advantages over skin fi
Publikováno v:
Purine and Pyrimidine Metabolism in Man V ISBN: 9781468412505
By incremental increase in the concentrations of inhibitors of essential biosynthetic pathways, a number of specific genes have been amplified in cultured mammalian cells. We have attempted to obtain an amplified phenotype by the progressive selectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::694dc795fbcbadf4018b065a82c495f8
https://doi.org/10.1007/978-1-4684-1248-2_43
https://doi.org/10.1007/978-1-4684-1248-2_43
Publikováno v:
Pediatric Research. 24:135-135
Mouse neuroblastoma cells (NB) have been adapted for growth in 1 mM mycophenolic acid (NB-myco) by incremental increases in drug concentration with each passage without mutagenesis. 50% growth inhibition occurred at 0.1 uM and 1 mM for NB and NB-myco
Publikováno v:
Pediatric Research. 19:758-758
Mouse neuroblastoma cells, NB, have been grown in increasing concentrations of mycophenolic acid for greater than 80 passages. A mycophenolic acid resistant neuroblastoma cell line (NB-MyR) has been isolated which is 1000-fold more resistant to mycop