Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Stephen D. Hess"'
Autor:
Lars Binkle-Ladisch, Andy Pironet, Andrea Zaliani, Chantal Alcouffe, Daniel Mensching, Undine Haferkamp, Anne Willing, Marcel S. Woo, Alexandre Erdmann, Timm Jessen, Stephen D. Hess, Philip Gribbon, Ole Pless, Rudi Vennekens, Manuel A. Friese
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111425- (2024)
Summary: Neurodegeneration in central nervous system disorders is linked to dysregulated neuronal calcium. Direct inhibition of glutamate-induced neuronal calcium influx, particularly via N-methyl-D-aspartate receptors (NMDAR), has led to adverse eff
Externí odkaz:
https://doaj.org/article/7c4743fbba874384a913ff92e62451a3
Autor:
Adam J. Davenport, Ioana Neagoe, Nico Bräuer, Markus Koch, Andrea Rotgeri, Jens Nagel, Alexis Laux-Biehlmann, Frederic Machet, Anne-Marie Coelho, Susan Boyce, Nikisha Carty, Mark J. Gemkow, Stephen D. Hess, Thomas M. Zollner, Oliver M. Fischer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract ATP-dependent P2X3 receptors play a crucial role in the sensitization of nerve fibers and pathological pain pathways. They are also involved in pathways triggering cough and may contribute to the pathophysiology of endometriosis and overacti
Externí odkaz:
https://doaj.org/article/db0e029d06d746b6aa334c9d4e1c736d
Autor:
Mark J. Gemkow, Jens Nagel, Nikisha Carty, Alexis Laux-Biehlmann, Ioana Neagoe, Thomas M. Zollner, Frederic Machet, Markus Koch, Adam James Davenport, Nico Bräuer, Andrea Rotgeri, Stephen D. Hess, Anne-Marie Coelho, Oliver Fischer, Susan Boyce
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
ATP-dependent P2X3 receptors play a crucial role in the sensitization of nerve fibers and pathological pain pathways. They are also involved in pathways triggering cough and may contribute to the pathophysiology of endometriosis and overactive bladde
Publikováno v:
Frontiers in Pharmacology, Vol 2 (2011)
Profiling of putative lead compounds against a representative panel of relevant enzymes, receptors, ion channels and transporters is a pragmatic approach to establish a preliminary view of potential issues that might later hamper development. An earl
Externí odkaz:
https://doaj.org/article/a073ea2b54544eefb8b5f520957e8318
Autor:
Seesha R. Takagishi, Anokhi Jambusaria-Pahlajani, Jay J. Liao, Madhu Shetti, Marvin Heyboer, Upendra Parvathaneni, Stephen D. Hess, George E. Laramore, Daniel Berg, Chrysalyne D. Schmults
Publikováno v:
Journal of Cancer Therapy. :824-835
Purpose: Post-operative radiotherapy (PORT) for resected cutaneous squamous cell carcinoma (CSCC) with perineural invasion (PNI) is controversial. Therefore, we conducted a survey to review treatment recommendations among Radiation Oncologists (ROs)
Autor:
Daniel Berg, Anokhi Jambusaria-Pahlajani, Kenneth A. Katz, Stephen D. Hess, Chrysalyne D. Schmults
Publikováno v:
Archives of Dermatology. 146:1225-1231
Objective To evaluate whether Mohs surgeons' management of high-risk cutaneous squamous cell carcinoma (HRCSCC) is uniform regarding radiologic nodal staging (RNS) and adjuvant radiation therapy (ART). Design A survey study of randomly selected, fell
Autor:
Jacqueline M. Junkins-Hopkins, Ellen J. Kim, Dipti Anand, Stephen D. Hess, Alain H. Rook, Rachel H. Gormley
Publikováno v:
Journal of the American Academy of Dermatology. 62:300-307
Cutaneous T-cell lymphomas most commonly have a CD4(+) memory T-cell phenotype with relatively indolent course, but may in rare cases present with a CD8(+) cytotoxic phenotype exhibiting strikingly more aggressive clinical behavior. We present two ca
Autor:
Stephen D. Hess, Alain H. Rook, Maria Wysocka, Julie H. Lin, Sarah M. Newton, Stephen K. Richardson, Jessica S. Yoon, Mariusz A. Wasik, Andrea B. Troxel, Bernice M. Benoit, Monika Kasprzycka
Publikováno v:
Journal of Investigative Dermatology. 128:473-480
IL-21, a common gamma-chain cytokine secreted by activated CD4+ T cells, influences both humoral and cell-mediated immune responses through the regulation of T, B, dendritic, and natural killer (NK) cells. Sézary syndrome is an advanced form of cuta
Autor:
Alain H. Rook, Ravi Ubriani, Joel M. Gelfand, Camille E. Introcaso, Malek Kamoun, Stephen D. Hess
Publikováno v:
Journal of the American Academy of Dermatology. 53:428-434
Background Because there are currently many effective therapies available for Sezary syndrome, close monitoring of disease progression is required in order for a clinician to know when to institute or change an intervention. It has been our clinical
Autor:
Fang-An Chen, Stephen D. Hess, Richard B. Bankert, Michael S. Sabel, Thomas F. Conway, Nejat K. Egilmez
Publikováno v:
Cancer Immunology, Immunotherapy. 54:944-952
Previous studies by others using transplantable murine tumor models have demonstrated that the administration of antibodies that block CTLA-4 interaction with B7 can provoke the elimination of established tumors, and that the tumor suppression is med