Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Stephen D Kachman"'
Autor:
Lianna R Walker, Taylor B Engle, Hiep Vu, Emily R Tosky, Dan J Nonneman, Timothy P L Smith, Tudor Borza, Thomas E Burkey, Graham S Plastow, Stephen D Kachman, Daniel C Ciobanu
Publikováno v:
PLoS Genetics, Vol 14, Iss 10, p e1007750 (2018)
Porcine circovirus 2 (PCV2) is a circular single-stranded DNA virus responsible for a group of diseases collectively known as PCV2 Associated Diseases (PCVAD). Variation in the incidence and severity of PCVAD exists between pigs suggesting a host gen
Externí odkaz:
https://doaj.org/article/6174445da06d44d49cef7e2b695350f1
Autor:
Baolong Liu, Phuong Linh Nguyen, Han Yu, Xingzhi Li, Huiren Wang, Tram Gia Bao Nguyen, Prakash Kumar Sahoo, Meghna Sur, Jay Reddy, Sarah Sillman, Stephen D. Kachman, Bara Altartouri, Guoqing Lu, Sathish Kumar Natarajan, Mahesh Pattabiraman, Jiujiu Yu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3661-3679 (2024)
Non-alcoholic steatohepatitis (NASH), an advanced form of non-alcoholic fatty liver disease (NAFLD), has emerged as the leading cause of liver failure and related death. Currently, no medication is specifically approved to treat NAFLD or NASH. Here w
Externí odkaz:
https://doaj.org/article/66b2c63f21974fa4b49f52be264308b3
Autor:
Joseph M Reed, Sean Olson, Danielle F Brees, Caitlin E Griffin, Ryan A Grove, Paul J Davis, Stephen D Kachman, Jiri Adamec, Greg A Somerville
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0207161 (2018)
The success of Staphylococcus aureus as a pathogen is due in part to its ability to adapt to changing environmental conditions using signal transduction pathways, such as metabolite- responsive regulators and two-component systems. S. aureus has a tw
Externí odkaz:
https://doaj.org/article/352bb418ed9341c3a714751e7868caa3
Autor:
Autumn M McKnite, Maria Elisa Perez-Munoz, Lu Lu, Evan G Williams, Simon Brewer, Pénélope A Andreux, John W M Bastiaansen, Xusheng Wang, Stephen D Kachman, Johan Auwerx, Robert W Williams, Andrew K Benson, Daniel A Peterson, Daniel C Ciobanu
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39191 (2012)
The gastrointestinal tract harbors a complex and diverse microbiota that has an important role in host metabolism. Microbial diversity is influenced by a combination of environmental and host genetic factors and is associated with several polygenic d
Externí odkaz:
https://doaj.org/article/f51bd453bfbc412996f86192dfb734f5
Autor:
Mahima T. Rasquinha, Kiruthiga Mone, Meghna Sur, Ninaad Lasrado, Chandirasegaran Massilamany, Stephen D. Kachman, David Steffen, Jay Reddy
Publikováno v:
Vaccines, Vol 12, Iss 3, p 266 (2024)
Group B coxsackieviruses (CVBs) cause a wide range of diseases in humans, but no vaccines are currently available to prevent these infections. Previously, we had demonstrated that a live attenuated CVB3 vaccine virus, Mutant 10 (Mt10), offers protect
Externí odkaz:
https://doaj.org/article/9e627bc61a304cd8a560a4821fd6b4ab
Autor:
Hatem Kittana, João C. Gomes-Neto, Kari Heck, Anthony F. Juritsch, Jason Sughroue, Yibo Xian, Sara Mantz, Rafael R. Segura Muñoz, Liz A. Cody, Robert J. Schmaltz, Christopher L. Anderson, Rodney A. Moxley, Jesse M. Hostetter, Samodha C. Fernando, Jennifer Clarke, Stephen D. Kachman, Clayton E. Cressler, Andrew K. Benson, Jens Walter, Amanda E. Ramer-Tait
Publikováno v:
mSphere, Vol 8, Iss 2 (2023)
ABSTRACT Enrichment of adherent-invasive Escherichia coli (AIEC) has been consistently detected in subsets of inflammatory bowel disease (IBD) patients. Although some AIEC strains cause colitis in animal models, these studies did not systematically c
Externí odkaz:
https://doaj.org/article/46c3fefc6c324ccd97461e0af0d7f5d4
Autor:
Débora G. Montezano, Thomas E. Hunt, Priscila M. Colombo da Luz, Kelsey Karnik, Stephen D. Kachman, Ana M. Vélez, Julie A. Peterson
Publikováno v:
Insects, Vol 14, Iss 6, p 524 (2023)
Exposure of lepidopteran pests to Bacillus thuringiensis (Bt) proteins has been shown to affect the behavior of larvae, including increased movement and avoidance of Bt-expressing plants or diet. Therefore, we hypothesized that the behavior of wester
Externí odkaz:
https://doaj.org/article/01386b90cb17471bb5ceb081b36d6a73
Autor:
Peterson, Débora G. Montezano, Thomas E. Hunt, Priscila M. Colombo da Luz, Kelsey Karnik, Stephen D. Kachman, Ana M. Vélez, Julie A.
Publikováno v:
Insects; Volume 14; Issue 6; Pages: 524
Exposure of lepidopteran pests to Bacillus thuringiensis (Bt) proteins has been shown to affect the behavior of larvae, including increased movement and avoidance of Bt-expressing plants or diet. Therefore, we hypothesized that the behavior of wester
Autor:
Christian W Eaton, Hiep L Vu, Arabella L Hodges, Seth P Harris, Stephen D Kachman, Daniel C Ciobanu
Publikováno v:
Journal of Animal Science.
Replication of porcine circovirus type 2 (PCV2), an important worldwide swine pathogen, has been demonstrated to be influenced by host genotype. Specifically, a missense DNA polymorphism (SYNGR2 p.Arg63Cys) within the SYNGR2 gene was demonstrated to
Autor:
Han Yu, Xingzhi Li, Baolong Liu, Jiujiu Yu, Xuan Shi, Stephen D. Kachman, You Zhou, Lili Jing, Xinghui Sun, Soonkyu Chung, Sophie Alvarez, Michael J. Naldrett, Seung Hyun Ro
Publikováno v:
Theranostics
Aberrant activation of the nucleotide-binding domain and leucine-rich repeat related (NLR) family, pyrin domain containing 3 (NLRP3) inflammasome drives the development of many complex inflammatory diseases, such as obesity, Alzheimer's disease, and