Zobrazeno 1 - 10
of 461
pro vyhledávání: '"Stephen D Hursting"'
Autor:
Michael F. Coleman, Eylem Kulkoyluoglu Cotul, Alexander J. Pfeil, Emily N. Devericks, Muhammad H. Safdar, Marvis Monteiro, Hao Chen, Alyssa N. Ho, Numair Attaar, Hannah M. Malian, Violet A. Kiesel, Alexis Ramos, Matthew Smith, Heena Panchal, Adam Mailloux, Dorothy Teegarden, Stephen D. Hursting, Michael K. Wendt
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-20 (2024)
Abstract Background Metabolic plasticity mediates breast cancer survival, growth, and immune evasion during metastasis. However, how tumor cell metabolism is influenced by and feeds back to regulate breast cancer progression are not fully understood.
Externí odkaz:
https://doaj.org/article/4bc52c528bb64c7f812b584380877b6e
Autor:
Kaylyn L Devlin, Tiffany Sanford, Lauren M Harrison, Paul LeBourgeois, Laura M Lashinger, Elizabeth Mambo, Stephen D Hursting
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159686 (2016)
MicroRNAs have emerged as ubiquitous post-transcriptional regulators that coordinate many fundamental processes within cells, including those commonly linked to cancer when dysregulated. Profiling microRNAs across stages of cancer progression provide
Externí odkaz:
https://doaj.org/article/5a2d28696c0f4d7887eb5e86cf8cd295
Autor:
Su Yon Jung, Mara Z Vitolins, Jenifer Fenton, Alexis C Frazier-Wood, Stephen D Hursting, Shine Chang
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121430 (2015)
Risk factors for obesity and weight gain are typically evaluated individually while "adjusting for" the influence of other confounding factors, and few studies, if any, have created risk profiles by clustering risk factors. We identified subgroups of
Externí odkaz:
https://doaj.org/article/5f6aa29cb6cb430ca03da8973e2dc969
Autor:
Laura W Bowers, Megan Wiese, Andrew J Brenner, Emily L Rossi, Rajeshwar R Tekmal, Stephen D Hursting, Linda A deGraffenried
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145452 (2015)
Obesity is associated with a worse breast cancer prognosis, while greater breast tumor estrogen receptor beta (ERβ) expression is correlated with improved therapy response and survival. The objective of this study was to determine the impact of obes
Externí odkaz:
https://doaj.org/article/b98b99f2ebdc48abb70b0892876d9aa7
Autor:
Alison E Harvey, Laura M Lashinger, Drew Hays, Lauren M Harrison, Kimberly Lewis, Susan M Fischer, Stephen D Hursting
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e94151 (2014)
Calorie restriction (CR) prevents obesity and has potent anticancer effects that may be mediated through its ability to reduce serum growth and inflammatory factors, particularly insulin-like growth factor (IGF)-1 and protumorigenic cytokines. IGF-1
Externí odkaz:
https://doaj.org/article/1df9c1ce63ff41d99cb2ae0528b50030
Autor:
Susan E Olivo-Marston, Stephen D Hursting, Susan N Perkins, Aaron Schetter, Mohammed Khan, Carlo Croce, Curtis C Harris, Jackie Lavigne
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94765 (2014)
Obesity is an established colon cancer risk factor, while preventing or reversing obesity via a calorie restriction (CR) diet regimen decreases colon cancer risk. Unfortunately, the biological mechanisms underlying these associations are poorly under
Externí odkaz:
https://doaj.org/article/304041ce981b4f93a01c13d9d55f87a2
Publikováno v:
Frontiers in Oncology, Vol 3 (2013)
The prevalence of obesity, an established risk and progression factor for many cancers, has increased dramatically in many countries over the past three decades. Worldwide, an estimated 600 million adults are currently obese. Thus, a better understan
Externí odkaz:
https://doaj.org/article/ca188ab93a124590b2bfb86451577818
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68089 (2013)
Obesity, prevalent in >35% of US women, is an established risk and progression factor for postmenopausal breast cancer, and strategies to break the obesity-breast cancer link are urgently needed. Approximately 30% of breast cancers carry p53 tumor su
Externí odkaz:
https://doaj.org/article/e5583cde72fe490d90baa5296d83dea8
Autor:
Yuan-yuan Li, Supradeep S. Madduri, Erika T. Rezeli, Charlene Santos, Herman Freeman III, Jing Peng, Susan L. McRitchie, Wimal Pathmasiri, Stephen D. Hursting, Susan J. Sumner, Delisha A. Stewart
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionObesity is a multi-factorial disease frequently associated with poor nutritional habits and linked to many detrimental health outcomes. Individuals with obesity are more likely to have increased levels of persistent inflammatory and metab
Externí odkaz:
https://doaj.org/article/33951a7561284ad3a43b615ec536c51b
Autor:
Alyssa N. Ho, Violet A. Kiesel, Claire E. Gates, Bennett H. Brosnan, Scott P. Connelly, Elaine M. Glenny, Alyssa J. Cozzo, Stephen D. Hursting, Michael Francis Coleman
Publikováno v:
Cells, Vol 13, Iss 10, p 806 (2024)
Triple-negative breast cancer (TNBC) lacks targeted therapies, leaving cytotoxic chemotherapy as the current standard treatment. However, chemotherapy resistance remains a major clinical challenge. Increased insulin-like growth factor 1 signaling can
Externí odkaz:
https://doaj.org/article/1ec0970c8673497f8d4cd59562421e0f