Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Stephen D, Robinson"'
Autor:
Christopher J. Benwell, Robert T. Johnson, James A. G. E. Taylor, Jordi Lambert, Stephen D. Robinson
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract Integrin trafficking to and from membrane adhesions is a crucial mechanism that dictates many aspects of a cell’s behaviour, including motility, polarisation, and invasion. In endothelial cells (ECs), the intracellular traffic of α5 integ
Externí odkaz:
https://doaj.org/article/71671c3a81fc4095bba9b64980907adb
Autor:
Nektarios K. Mazarakis, Stephen D. Robinson, Priyank Sinha, Christos Koutsarnakis, Spyridon Komaitis, George Stranjalis, Susan C. Short, Paul Chumas, Georgios Giamas
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 46, Iss , Pp 100761- (2024)
High grade gliomas are the most common primary aggressive brain tumours with a very poor prognosis and a median survival of less than 2 years. The standard management protocol of newly diagnosed glioblastoma patients involves surgery followed by radi
Externí odkaz:
https://doaj.org/article/ad5baf5a520642be8dd50b97972492c0
Autor:
Alastair M. McKee, Benjamin M. Kirkup, Matthew Madgwick, Wesley J. Fowler, Christopher A. Price, Sally A. Dreger, Rebecca Ansorge, Kate A. Makin, Shabhonam Caim, Gwenaelle Le Gall, Jack Paveley, Charlotte Leclaire, Matthew Dalby, Cristina Alcon-Giner, Anna Andrusaite, Tzu-Yu Feng, Martina Di Modica, Tiziana Triulzi, Elda Tagliabue, Simon W.F. Milling, Katherine N. Weilbaecher, Melanie R. Rutkowski, Tamás Korcsmáros, Lindsay J. Hall, Stephen D. Robinson
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103012- (2021)
Summary: The gut microbiota’s function in regulating health has seen it linked to disease progression in several cancers. However, there is limited research detailing its influence in breast cancer (BrCa). This study found that antibiotic-induced p
Externí odkaz:
https://doaj.org/article/2e86b553d51f40f4b0d717c1e699887e
Autor:
Abdullah A. A. Alghamdi, Christopher J. Benwell, Samuel J. Atkinson, Jordi Lambert, Robert T. Johnson, Stephen D. Robinson
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Angiogenesis relies on the ability of endothelial cells (ECs) to migrate over the extracellular matrix via integrin receptors to respond to an angiogenic stimulus. Of the two neuropilin (NRP) orthologs to be identified, both have been reported to be
Externí odkaz:
https://doaj.org/article/c0060822154a4990b649b695f8e8a3d8
Autor:
Raymond Kiu, Alexander G. Shaw, Kathleen Sim, Antia Acuna-Gonzalez, Christopher A. Price, Harley Bedwell, Sally A. Dreger, Wesley J. Fowler, Emma Cornwell, Derek Pickard, Gusztav Belteki, Jennifer Malsom, Sarah Phillips, Gregory R. Young, Zoe Schofield, Cristina Alcon-Giner, Janet E. Berrington, Christopher J. Stewart, Gordon Dougan, Paul Clarke, Gillian Douce, Stephen D. Robinson, J. Simon Kroll, Lindsay J. Hall
Clostridium perfringens is an anaerobic toxin-producing bacterium associated with intestinal diseases, particularly in neonatal humans and animals. Infant gut microbiome studies have recently indicated a link between C. perfringens and the preterm in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99cb2b07e2fd2a5bdf9eb9e6d97321b
https://www.repository.cam.ac.uk/handle/1810/350553
https://www.repository.cam.ac.uk/handle/1810/350553
Autor:
Stephen D. Robinson, Christopher A. Price, James A.G.E. Taylor, Robert T. Johnson, Christopher J. Benwell
Angiogenesis is inhibited in PyMT-BO1 tumours upon NRP1 and NRP2 depletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc41ca5a7fcb3191384d581bb6ccee9
https://doi.org/10.1158/2767-9764.22546179.v1
https://doi.org/10.1158/2767-9764.22546179.v1
Autor:
Melanie R. Rutkowski, Stephen D. Robinson, Wesley J. Fowler, Stephanie Greenfield, Maureen A. Carey, Sree H. Kolli, Audrey M. Putelo, Mitchell T. McGinty, Claire Buchta Rosean, Sally A. Dreger, Francesca N. Azar, Tzu-Yu Feng
Establishing commensal dysbiosis, defined as an inflammatory gut microbiome with low biodiversity, before breast tumor initiation, enhances early dissemination of hormone receptor–positive (HR+) mammary tumor cells. Here, we sought to determine whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52f83f1eb39f7e5fea6d49a48811db5
https://doi.org/10.1158/2326-6066.c.6551030.v1
https://doi.org/10.1158/2326-6066.c.6551030.v1
Autor:
Stephen D. Robinson, Christopher A. Price, James A.G.E. Taylor, Robert T. Johnson, Christopher J. Benwell
Neuropilin (NRP) expression is highly correlated with poor outcome in multiple cancer subtypes. As known coreceptors for VEGFRs, core drivers of angiogenesis, past investigations have alluded to their functional roles in facilitating tumorigenesis by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc2214408cef5f8225e0e1682ecd706
https://doi.org/10.1158/2767-9764.c.6551115.v1
https://doi.org/10.1158/2767-9764.c.6551115.v1
Autor:
Melanie R. Rutkowski, Stephen D. Robinson, Wesley J. Fowler, Stephanie Greenfield, Maureen A. Carey, Sree H. Kolli, Audrey M. Putelo, Mitchell T. McGinty, Claire Buchta Rosean, Sally A. Dreger, Francesca N. Azar, Tzu-Yu Feng
Supplementary Figure from Reciprocal Interactions Between the Gut Microbiome and Mammary Tissue Mast Cells Promote Metastatic Dissemination of HR+ Breast Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef353a470e68f376afe3e1f4bce41f05
https://doi.org/10.1158/2326-6066.22545764
https://doi.org/10.1158/2326-6066.22545764
Autor:
Stephen D. Robinson, Christopher A. Price, James A.G.E. Taylor, Robert T. Johnson, Christopher J. Benwell
Co-targeting NRP1 and NRP2 inhibits tumour growth and angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5dd601d1158d2ee0036599f40a065f
https://doi.org/10.1158/2767-9764.22546182.v1
https://doi.org/10.1158/2767-9764.22546182.v1