Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stephen Christopher Finch"'
Publikováno v:
Handbook of Comparative Pharmacokinetics and Residues of Veterinary Antimicrobials ISBN: 9781351071055
The beta lactam antibiotics include the penicillins and cephalosporins. Penicillin has the distinction of being the first clinically useful antibiotic. Since its first therapeutic trial in 1941, it has become the foundation on which many other semisy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5903c3ca28f1c5dbb8bb55b35f8fb77
https://doi.org/10.1201/9781351071055-3
https://doi.org/10.1201/9781351071055-3
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 8:573-576
This paper reports the direct examination of rat bile by 1 H NMR and the detection and characterization of a metabolite of BRL 41897A using untreated samples. Subsequent purification of the compound by preparative HPLC and structure confirmation stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e493005718248977b28201a888e3bb
https://doi.org/10.1016/0731-7085(90)80082-z
https://doi.org/10.1016/0731-7085(90)80082-z
Publikováno v:
ChemInform. 21
The syntheses and biological activities of potassium (3RS)-3- [(2R)-2-(4-ethyl-2,3-dioxopiperazin-1-ylcarboxamido)-2-phenylacetamido]-3- formamido-2-oxoazetidine-1-sulphonate and potassium (3RS)-3-[(Z)-2-(2- aminothiazol-4-yl)-2-methoxyiminoacetamido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a393cee60ab9a24f10dd8353eb6bdfef
https://doi.org/10.1002/chin.199005309
https://doi.org/10.1002/chin.199005309
Autor:
Roger J. Ponsford, Stephen Christopher Finch, Terence C. Smale, Michael J. Pearson, Clive Leslie Branch, Peter H. Milner, Angela W. Guest, Michael J. Basker
Publikováno v:
The Journal of Antibiotics. 39:1788-1791
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0df97894a6f89794fe3d59b76b131c
https://doi.org/10.7164/antibiotics.39.1788
https://doi.org/10.7164/antibiotics.39.1788
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :1491-1498
Addition of the mixed anhydride derived from azidoacetic acid and trifluoroacetic anhydride to benzyl 2-(N-phenylpropynylideneamino)-3,3-ethylenedioxybutanoate (9) in the presence of triethylamine afforded (3RS,4SR)-3-azido-1-(1-benzyloxycarbonyl-2,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cae821cfc5fafcea2e9f7cc3aa89bda4
https://doi.org/10.1039/p19850001491
https://doi.org/10.1039/p19850001491
Publikováno v:
Tetrahedron Letters. 23:4381-4384
Tricyclic triazolocephem and triazolopenam carboxylic acids have been synthesized, but only the former exhibited antibacterial activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df730ea13d9c1bea54273ea6b39a71e7
https://doi.org/10.1016/s0040-4039(00)85607-5
https://doi.org/10.1016/s0040-4039(00)85607-5
Autor:
Clive Leslie Branch, Stephen Christopher Finch, Michael J. Pearson, Roger J. Ponsford, Angela W. Guest, Peter H. Milner, Terence C. Smale, Arun C. Kaura
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :45-55
The preparation of novel antibacterially active 7α-formamido cephalosporins from the corresponding 7α-(methylthio) analogues by mercury (II)-mediated displacement with ammonia and subsequent formylation is described. The amine (2), a versatile inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1405db6ea28b8ed2a20f4bc20d160379
https://doi.org/10.1039/p19870000045
https://doi.org/10.1039/p19870000045
Publikováno v:
Tetrahedron Letters. 30:3219-3222
The syntheses and biological activities of potassium (3RS)-3- [(2R)-2-(4-ethyl-2,3-dioxopiperazin-1-ylcarboxamido)-2-phenylacetamido]-3- formamido-2-oxoazetidine-1-sulphonate and potassium (3RS)-3-[(Z)-2-(2- aminothiazol-4-yl)-2-methoxyiminoacetamido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07fab778fb8b5c5bb9b10ed39afa114d
https://doi.org/10.1016/s0040-4039(00)99206-2
https://doi.org/10.1016/s0040-4039(00)99206-2
Autor:
Stephen Christopher Finch, Arun C. Kaura, Peter H. Milner, Michael J. Pearson, Michael J. Basker, Frank P. Harrington, A. W. Guest, Clive Leslie Branch, Sarah J. Knott
Publikováno v:
The Journal of Antibiotics. 40:646-651
The synthesis and antibacterial activity of 7 beta-[D-2-(aryl)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl) carbonylamino] acetamido]-7 alpha-formamidocephalosporins with various substituents at the C-3 position of the cephalosporin nucleus is described. Inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7a5ba219e811f20b8e596934ef150e
https://doi.org/10.7164/antibiotics.40.646
https://doi.org/10.7164/antibiotics.40.646
Autor:
Terence C. Smale, Stephen Christopher Finch, Arun C. Kaura, Roger J. Ponsford, Angela W. Guest, Michael J. Pearson, Clive Leslie Branch, Peter H. Milner
Publikováno v:
ChemInform. 18
Acylation of the amine (I) gives the cephalosporanates (III), whose methylthio group is replaced by formamido in a two-step process to give the formamides (V), which are converted to their sodium salts (VIa).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebb5199fb717736cf9846329fd2331fb
https://doi.org/10.1002/chin.198721298
https://doi.org/10.1002/chin.198721298