Zobrazeno 1 - 10
of 394
pro vyhledávání: '"Stephen Cho"'
Autor:
John Akrofi Kubi, Augustine Suurinobah Brah, Kenneth Man Chee Cheung, Yin Lau Lee, Kai-Fai Lee, Stephen Cho Wing Sze, Wei Qiao, Kelvin Wai-Kwok Yeung
Publikováno v:
Bioactive Materials, Vol 27, Iss , Pp 429-446 (2023)
Delayed bone defect repairs lead to severe health and socioeconomic impacts on patients. Hence, there are increasing demands for medical interventions to promote bone defect healing. Recombinant proteins such as BMP-2 have been recognized as one of t
Externí odkaz:
https://doaj.org/article/7baa5005eb264f2b900fd29db3b68b6d
Autor:
Zhenguang Ying, Kaifang Wang, Junfeng Wu, Mingyu Wang, Jing Yang, Xia Wang, Guowei Zhou, Haibin Chen, Hongwu Xu, Stephen Cho Wing Sze, Feng Gao, Chunman Li, Ou Sha
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-21 (2022)
Abstract Background The centrosome is one of the most important non-membranous organelles regulating microtubule organization and progression of cell mitosis. The coiled-coil alpha-helical rod protein 1 (CCHCR1, also known as HCR) gene is considered
Externí odkaz:
https://doaj.org/article/477a18e6a70b43539ffeb2203bccdd7e
Autor:
Ka Man Yip, Kwan Ming Lee, Tzi Bun Ng, Shujun Xu, Ken Kin Lam Yung, Shaogang Qu, Allen Ka Loon Cheung, Stephen Cho Wing Sze
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-20 (2022)
Abstract Background Since the outbreak of COVID-19 has resulted in over 313,000,000 confirmed cases of infection and over 5,500,000 deaths, substantial research work has been conducted to discover agents/ vaccines against COVID-19. Undesired adverse
Externí odkaz:
https://doaj.org/article/7ea8a37b54314cf1aa8e4f129b292a44
Autor:
Zhu Zhang, Wen-Qing Chen, Shi-Qing Zhang, Jing-Xuan Bai, Ching-Lam Lau, Stephen Cho-Wing Sze, Ken Kin-Lam Yung, Joshua Ka-Shun Ko
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pancreatic cancer is amongst the most lethal malignancies, while its poor prognosis could be associated with promotion of autophagy and the tumor immune microenvironment. Studies have confirmed the pro-tumorigenic nature of the cathelicidin family of
Externí odkaz:
https://doaj.org/article/76ea504c5e1a4d11920d520ab3a55c07
Autor:
Kaili Lin, Stephen Cho-Wing Sze, Bin Liu, Zhang Zhang, Zhu Zhang, Peili Zhu, Ying Wang, Qiudi Deng, Ken Kin-Lam Yung, Shiqing Zhang
Publikováno v:
Journal of Ginseng Research, Vol 45, Iss 2, Pp 325-333 (2021)
Background: Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders. Enhancing hippocampal neurogenesis by promoting proliferation and differentiation of neural stem cells (NSCs) is a promising therapeutic strategy for AD. 2
Externí odkaz:
https://doaj.org/article/89d76940d68748fc94c7c57ad9e61b4f
Autor:
Junkui Li, Peili Zhu, Yifei Chen, Shiqing Zhang, Zhu Zhang, Zhang Zhang, Ying Wang, Xiaoli Jiang, Kaili Lin, Wei Wu, Zhixian Mo, Stephen Cho Wing Sze, Ken Kin Lam Yung
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Colorectal cancer (CRC) is an aggressive cancer. Isoalantolactone (IATL) has been reported to exert cytotoxicity against various cancer cells, but not CRC. In this study, we explored the anti-CRC effects and mechanism of action of IATL in vitro and i
Externí odkaz:
https://doaj.org/article/d9f5cb620b424cb28c9cd1eac38d1a26
Autor:
Kaifang Wang, Xiaona Wang, Minghuan Zhang, Zhenguang Ying, Zeyao Zhu, Kin Yip Tam, Chunman Li, Guowei Zhou, Feng Gao, Meiqi Zeng, Stephen Cho Wing Sze, Xia Wang, Ou Sha
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1416 (2023)
Trichosanthin (TCS) is a type I ribosome-inactivating protein extracted from the tuberous root of the plant Trichosanthes. TCS shows promising potential in clinical drug abortion, anti-tumor and immunological regulation. However, the molecular mechan
Externí odkaz:
https://doaj.org/article/5f0dfb391a48491abd91bef2941193f5
Autor:
Stephen Cho Wing Sze, Liang Zhang, Shiqing Zhang, Kaili Lin, Tzi Bun Ng, Man Ling Ng, Kai-Fai Lee, Jenny Ka Wing Lam, Zhang Zhang, Ken Kin Lam Yung
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12689 (2022)
We report herein a novel mechanism, unraveled by proteomics and validated by in vitro and in vivo studies, of the aberrant aging-associated upregulation of ovarian transferrin and ferritin in rat ovaries. The ovarian mass and serum estradiol titer pl
Externí odkaz:
https://doaj.org/article/798cde20af354469a1cc3598765e97c3
Autor:
Jun-Kui Li, Hai-Tao Sun, Xiao-Li Jiang, Yi-Fei Chen, Zhu Zhang, Ying Wang, Wen-Qing Chen, Zhang Zhang, Stephen Cho Wing Sze, Pei-Li Zhu, Ken Kin Lam Yung
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11890 (2022)
Polyphyllin II (PPII) is a natural steroidal saponin occurring in Rhizoma Paridis. It has been demonstrated to exhibit anti-cancer activity against a variety of cancer cells. However, the anti-colorectal cancer (CRC) effects and mechanism of action o
Externí odkaz:
https://doaj.org/article/09816c8c70d6416598e647feaf2d604c
Autor:
Shiqing Zhang, Xiaoli Jiang, Ying Wang, Kaili Lin, Zhang Zhang, Zhu Zhang, Peili Zhu, Man Ling Ng, Shaogang Qu, Stephen Cho Wing Sze, Ken Kin Lam Yung
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
An-Gong-Niu-Huang Wan (AGNHW), a famous formula in traditional Chinese medicine, has been clinically used for centuries for treating cerebral diseases, but the protective effects of pre-treatment with AGNHW on cerebral ischemia have not yet been repo
Externí odkaz:
https://doaj.org/article/4d0209ac91c34a7794994e7b2b6f25b8