Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stephen Chelko"'
Autor:
Stephen Chelko, Daniel Fay
Publikováno v:
Patient Experience Journal, Vol 9, Iss 3 (2022)
As an academic researcher, my work-life revolves around testing the efficaciousness of pharmaceutical drugs on the prevention of cardiac dysfunction, arrhythmias, and sudden cardiac death in animal models of heart disease. I never thought I would go
Externí odkaz:
https://doaj.org/article/8c11cde6dfbe4477b4bf778d9cc5cafb
Autor:
Jacopo Agrimi, Cristina Spalletti, Carlotta Baroni, Gizem Keceli, Guangshuo Zhu, Angela Caragnano, Marco Matteucci, Stephen Chelko, Genaro A. Ramirez-Correa, Djahida Bedja, Valentina Casieri, Nicole Di Lascio, Arianna Scalco, Antonio Paolo Beltrami, Nazareno Paolocci, Matteo Caleo, Vincenzo Lionetti
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 384-401 (2019)
Introduction: Obesity and psychosocial stress (PS) co-exist in individuals of Western society. Nevertheless, how PS impacts cardiac and hippocampal phenotype in obese subjects is still unknown. Nor is it clear whether changes in local brain-derived n
Externí odkaz:
https://doaj.org/article/344bbb4dd2b84f019ca7f7ef6fbf2bd0
Autor:
Gun-Sik Cho, Dong I. Lee, Emmanouil Tampakakis, Sean Murphy, Peter Andersen, Hideki Uosaki, Stephen Chelko, Khalid Chakir, Ingie Hong, Kinya Seo, Huei-Sheng Vincent Chen, Xiongwen Chen, Cristina Basso, Steven R. Houser, Gordon F. Tomaselli, Brian O’Rourke, Daniel P. Judge, David A. Kass, Chulan Kwon
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 571-582 (2017)
Summary: Pluripotent stem cells (PSCs) offer unprecedented opportunities for disease modeling and personalized medicine. However, PSC-derived cells exhibit fetal-like characteristics and remain immature in a dish. This has emerged as a major obstacle
Externí odkaz:
https://doaj.org/article/04ac548333594c669d794d791d77417d
Publikováno v:
Cureus.
Publikováno v:
International Journal of Molecular Sciences. 23:8753
Arrhythmogenic Cardiomyopathy (ACM), a Mendelian disorder that can affect both left and right ventricles, is most often associated with pathogenic desmosomal variants that can lead to fibrofatty replacement of the myocardium, a pathological hallmark
Autor:
Julia Cadrin-Tourigny, Laurens P Bosman, Anna Nozza, Weijia Wang, Rafik Tadros, Aditya Bhonsale, Mimount Bourfiss, Annik Fortier, Øyvind H Lie, Ardan M Saguner, Anneli Svensson, Antoine Andorin, Crystal Tichnell, Brittney Murray, Katja Zeppenfeld, Maarten P van den Berg, Folkert W Asselbergs, Arthur A M Wilde, Andrew D Krahn, Mario Talajic, Lena Rivard, Stephen Chelko, Stefan L Zimmerman, Ihab R Kamel, Jane E Crosson, Daniel P Judge, Sing Chien Yap, Jeroen F van der Heijden, Harikrishna Tandri, Jan D H Jongbloed, Marie Claude Guertin, J Peter van Tintelen, Pyotr G Platonov, Firat Duru, Kristina H Haugaa, Paul Khairy, Richard N W Hauer, Hugh Calkins, Anneline S J M te Riele, Cynthia A James
Publikováno v:
European heart journal, 40(23), 1850-1858. Oxford University Press
European Heart Journal, 40(23), 1850-1858. OXFORD UNIV PRESS
European Heart Journal, 40(23), 1850-1858. Oxford University Press
European Heart Journal, 43(32). Oxford University Press
European heart journal, 43(32), E1-E9. Oxford University Press
European Heart Journal, 40(23), 1850. Oxford University Press
European Heart Journal, 40(23), 1850-1858. OXFORD UNIV PRESS
European Heart Journal, 40(23), 1850-1858. Oxford University Press
European Heart Journal, 43(32). Oxford University Press
European heart journal, 43(32), E1-E9. Oxford University Press
European Heart Journal, 40(23), 1850. Oxford University Press
Aims Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is characterized by ventricular arrhythmias (VAs) and sudden cardiac death (SCD). We aimed to develop a model for individualized prediction of incident VA/SCD in ARVC patients. Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38b4b26167e7959e9427ba20e165c7b
https://dspace.library.uu.nl/handle/1874/385509
https://dspace.library.uu.nl/handle/1874/385509
Publikováno v:
Circulation. 130
Reduced signal at intercalated discs (IDs) and nuclear accumulation of the desmosomal protein plakoglobin (γ-catenin) in arrhythmogenic cardiomyopathy (ACM) have been linked to suppression of canonical Wnt/β-catenin signaling. In a chemical screen