Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Stephen C. Schmechel"'
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Figure 4 - PDF file 111K, Reduction of Wnt signaling by β-catenin knockdown or GSK3B overexpression reduces tumor growth in xenograft models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bce1b4500ae8aa47f763841e42aa42b
https://doi.org/10.1158/2159-8290.22530711
https://doi.org/10.1158/2159-8290.22530711
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Table 2 - PDF 69K, QPCR primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f54fa0e01e8181316838630811d03c
https://doi.org/10.1158/2159-8290.22530705
https://doi.org/10.1158/2159-8290.22530705
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Figure 2 - PDF file 109K, Overexpression of activated β-catenin and knockdown of AXIN1 or GSK3B results in increased Wnt signaling and an induction of oncogenic properties in immortalized human Schwann cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e365a917fcd11f9e3331f28e9d12a11
https://doi.org/10.1158/2159-8290.22530717.v1
https://doi.org/10.1158/2159-8290.22530717.v1
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Table and Figure Legends-PDF file 123K, Supplementary Table and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccc12018854f2621735d0c850c71419
https://doi.org/10.1158/2159-8290.22530702.v1
https://doi.org/10.1158/2159-8290.22530702.v1
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Figure 1 - PDF file 141K, Human tissue microarray shows that C-MYC staining intensity increases with tumor progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c5c5d9446810b9576443f5768e5a98
https://doi.org/10.1158/2159-8290.22530723.v1
https://doi.org/10.1158/2159-8290.22530723.v1
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Table 1 - PDF 95K, Genes listed were identified in a murine SB screen for drivers of Schwann cell tumorigenesis, and all have known roles in canonical Wnt/β-catenin signaling. Listed are the percentage of neurofibromas or MPNSTs with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1556eae348360ad89fa96b2f74177232
https://doi.org/10.1158/2159-8290.22530708.v1
https://doi.org/10.1158/2159-8290.22530708.v1
Autor:
David A. Largaespada, Aaron L. Sarver, Michael D. Taylor, Annie Huang, David J. Odde, Robert J. Wechsler-Reya, Robert B. Jenkins, Charles G. Eberhart, Stephen C. Schmechel, Anthony E. Rizzardi, Michelle M. Frees, Addison M. Demer, Amy M. Molan, Ryan D. Krebs, Quincy Rosemarie, Fausto J. Rodriguez, Xiaochong Wu, Daniel Picard, Branden S. Moriarity, Adrian M. Dubuc, Paramita Das, Barbara R. Tschida, Catherine Lee, Jun Wang, Rory L. Williams, George M. Otto, Ghaidan A. Shamsan, Eric P. Rahrmann, Sandra Wagner, Jason P. Ostergaard, Alex T. Larsson, Jon D. Larson, Pauline J. Beckmann
Medulloblastoma and central nervous system primitive neuroectodermal tumors (CNS-PNET) are aggressive, poorly differentiated brain tumors with limited effective therapies. Using Sleeping Beauty (SB) transposon mutagenesis, we identified novel genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebcfc7720d1848ea19440c3e7a8f431f
https://doi.org/10.1158/0008-5472.c.6511413.v1
https://doi.org/10.1158/0008-5472.c.6511413.v1
Autor:
David A. Largaespada, Aaron L. Sarver, Michael D. Taylor, Annie Huang, David J. Odde, Robert J. Wechsler-Reya, Robert B. Jenkins, Charles G. Eberhart, Stephen C. Schmechel, Anthony E. Rizzardi, Michelle M. Frees, Addison M. Demer, Amy M. Molan, Ryan D. Krebs, Quincy Rosemarie, Fausto J. Rodriguez, Xiaochong Wu, Daniel Picard, Branden S. Moriarity, Adrian M. Dubuc, Paramita Das, Barbara R. Tschida, Catherine Lee, Jun Wang, Rory L. Williams, George M. Otto, Ghaidan A. Shamsan, Eric P. Rahrmann, Sandra Wagner, Jason P. Ostergaard, Alex T. Larsson, Jon D. Larson, Pauline J. Beckmann
Figure S4. Shows ARHGAP36 expression in mouse and human neural tissue. Figure S5. Shows characterization of ARHGAP36 and Megf10 in C17.2 cells Figures S6-S7 show mechanistic analysis of FOXR2 in C17.2 and HSC1L cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c88fb8090e9d0f93c8d64bec0f20df6
https://doi.org/10.1158/0008-5472.22423053
https://doi.org/10.1158/0008-5472.22423053
Autor:
David A. Largaespada, Aaron L. Sarver, Michael D. Taylor, Annie Huang, David J. Odde, Robert J. Wechsler-Reya, Robert B. Jenkins, Charles G. Eberhart, Stephen C. Schmechel, Anthony E. Rizzardi, Michelle M. Frees, Addison M. Demer, Amy M. Molan, Ryan D. Krebs, Quincy Rosemarie, Fausto J. Rodriguez, Xiaochong Wu, Daniel Picard, Branden S. Moriarity, Adrian M. Dubuc, Paramita Das, Barbara R. Tschida, Catherine Lee, Jun Wang, Rory L. Williams, George M. Otto, Ghaidan A. Shamsan, Eric P. Rahrmann, Sandra Wagner, Jason P. Ostergaard, Alex T. Larsson, Jon D. Larson, Pauline J. Beckmann
Characterization of SB-induced medulloblastomas and CNS-PNETs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcf71417a72492031f7dbb0484851a0
https://doi.org/10.1158/0008-5472.22423056.v1
https://doi.org/10.1158/0008-5472.22423056.v1
Autor:
Haojie Huang, Donald J. Tindall, Jan Van Deursen, John C. Cheville, Stephen C. Schmechel, Jun Zhang, Liang Cheng, Anthony Rizzardi, Chunrong Yu, Liguo Wang, Kevin M. Regan, Jian Zhong, Yunqian Pan, Ping Liu, Shuai Chen, Liya Ding
PDF file - 66KB, Supplemental Table S2. The incidence of prostatic intraepithelial neoplasia (PIN) lesions detected in prostate-specific Cbp homozygous and Pten heterozygous deletion (Cbppc-/-;Ptenpc+/-) mice at 4 and 6 months of age and their litter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fa618afa4b1adacf9eaab6bb9a23d7
https://doi.org/10.1158/0008-5472.22401347
https://doi.org/10.1158/0008-5472.22401347