Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stephen C. McNeill"'
Autor:
Jim E. Riviere, Alfred O. Inman, Michael L. Francoeur, Nancy A. Monteiro-Riviere, Stephen C. McNeill
Publikováno v:
Pharmaceutical Research. 10:1326-1331
The mechanism of the topical delivery of piroxicam, a nonsteroidal antiinflammatory drug, has been controversial as to whether systemic absorption is required for topical efficacy. This study, using in vivo pigs treated with topical 3H-piroxicam gel,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53ceac05370742dc0423a2218836a2a8
https://doi.org/10.1023/a:1018973814456
https://doi.org/10.1023/a:1018973814456
Publikováno v:
Pharmaceutical Research. :1422-1427
There is considerable uncertainty over whether and to what extent topically applied drugs can be delivered directly to anatomical sites beneath the skin, without prior entry into the systemic blood circulation. The in vivo studies reported in this wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b2542635d055700000ea7106b998a6b
https://doi.org/10.1023/a:1015854728278
https://doi.org/10.1023/a:1015854728278
Publikováno v:
Pharmaceutical Research. :33-39
Using excised human skin and tissue grafted to athymic mice, the in vitro and in vivo delivery and metabolism of a salicylate diester were compared. Concentration profiles of this drug and its metabolites were obtained for the outer several hundred m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ea085e559bda3a8941465634d0bc81
https://doi.org/10.1023/a:1015891400924
https://doi.org/10.1023/a:1015891400924
Publikováno v:
Pharmaceutical Research. :119-124
The steady-state flux and skin tissue distribution of a topically applied diester of salicylic acid was measured in vitro in the presence and absence of an esterase inhibitor. When compared with data obtained previously under in vivo conditions, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a10001c3c393c12d75176df1cf6ef1
https://doi.org/10.1023/a:1015924408193
https://doi.org/10.1023/a:1015924408193
Autor:
Michael F. Holick, Jane Frommer, Neil M. Richtand, John T. Potts, Stephen C. McNeill, Sally Ann Holick, John W. Henley
Publikováno v:
Biochemistry. 18(6)
The process of the photolytic activation of vitamin D precursor(s) in the skin has been elucidated by a detailed analysis of the products formed after ultraviolet light exposure. The photolytic product isolated from the skin of rats exposed to ultrav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f865500569f767e14ee2fab436d8678
https://pubmed.ncbi.nlm.nih.gov/218609
https://pubmed.ncbi.nlm.nih.gov/218609