Editorial: Vulnerability and resilience of marine ecosystems affected by the Deepwater Horizon oil spill

Autor: Donald F. Boesch, Just Cebrian, Vanessa F. Fonseca, Stephen C. Landers, N. Justin Marshall

Publikováno v: Frontiers in Marine Science, Vol 10 (2023)

Externí odkaz: https://doaj.org/article/f8a8e43237434ce9bd357b833e7c9177

Epithelial Na+ channel activity in human airway epithelial cells: the role of serum and glucocorticoid-inducible kinase 1

Autor: Stephen C. Land, Agustin Garcia Caballero, Stuart M. Wilson, Gordon B. Watt, Noor Akmal Shareela Ismail

Publikováno v: British Journal of Pharmacology. 166:1272-1289

BACKGROUND AND PURPOSE Glucocorticoids appear to control Na+ absorption in pulmonary epithelial cells via a mechanism dependent upon serum and glucocorticoid-inducible kinase 1 (SGK1), a kinase that allows control over the surface abundance of epithe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bccbf2fb7d84521aaf17cc6cc6cb9a5
https://doi.org/10.1111/j.1476-5381.2012.01860.x

Absence of the Birt-Hogg-Dube gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

Autor: Tjinta Brinkhuizen, Arnim Pause, Rachael S. Preston, Andrew R. Tee, David Mark Davies, Elaine A. Dunlop, Anders Bondo Dydensborg, M.A.M. van Steensel, Stephen C. Land, Lieke Gijezen, Fred H. Menko, K. T. Harper, Andrew Philp, Keith Baar, Tijs Claessens

Publikováno v: Oncogene, 30(10), 1159-1173. Nature Publishing Group
Preston, R S, Philp, A, Claessens, T, Gijezen, L, Dydensborg, A B, Dunlop, E A, Harper, K T, Brinkhuizen, T, Menko, F H, Davies, D M, Land, S C, Pause, A, Baar, K, van Steensel, M A M & Tee, A R 2011, ' Absence of the Birt-Hogg-Dube gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility ', Oncogene, vol. 30, no. 10, pp. 1159-1173 . https://doi.org/10.1038/onc.2010.497

Under conditions of reduced tissue oxygenation, hypoxia-inducible factor (HIF) controls many processes, including angiogenesis and cellular metabolism, and also influences cell proliferation and survival decisions. HIF is centrally involved in tumour

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d787e3e5f0995aaedf4ee6b1d6c89a
https://hdl.handle.net/1871/36585

Redox Regulation of Lung Development and Perinatal Lung Epithelial Function

Autor: Stephen C. Land, Stuart M. Wilson

Publikováno v: Antioxidants & Redox Signaling. 7:92-107

Throughout gestation, low oxygen tensions are a dominant feature of the fetal environment and so may be important in sustaining a normal pattern of lung morphogenesis until the moment of birth. As breathing begins, the equilibration of the lung lumen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0a1e6b0997b7186fdfe190b0a72fa1
https://doi.org/10.1089/ars.2005.7.92

Thymulin evokes IL-6-C/EBPβ regenerative repair and TNF-α silencing during endotoxin exposure in fetal lung explants

Autor: Froogh Darakhshan, Stephen C. Land

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 286:L473-L487

Chorioamnionitis is associated with increased risks of perinatal respiratory failure; however, components of the inflammatory acute-phase response are known to actively promote lung maturation. To manipulate this relationship, we examined the effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700f9cfbe0638a0dd236982e4e2db53e
https://doi.org/10.1152/ajplung.00401.2002