Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stephen C. Kolwicz Jr."'
Autor:
Bo Zhou, Arianne Caudal, Xiaoting Tang, Juan D. Chavez, Timothy S. McMillen, Andrew Keller, Outi Villet, Mingyue Zhao, Yaxin Liu, Julia Ritterhoff, Pei Wang, Stephen C. Kolwicz Jr., Wang Wang, James E. Bruce, Rong Tian
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
In hypertrophied and failing hearts, fuel metabolism is reprogrammed to increase glucose metabolism, especially glycolysis. This metabolic shift favors biosynthetic function at the expense of ATP production. Mechanisms responsible for the switch are
Externí odkaz:
https://doaj.org/article/42430db1c8a448f4bb8c08df2e4cb07e
Autor:
Lola E. Holcomb, Patrick Rowe, Caitlin C. O’Neill, Elizabeth A. DeWitt, Stephen C. Kolwicz Jr.
Publikováno v:
Physiological Reports, Vol 10, Iss 3, Pp n/a-n/a (2022)
Abstract Previous studies suggest that sex differences in lipid metabolism exist with females demonstrating a higher utilization of lipids during exercise, which is mediated partly by increased utilization of muscle triglycerides. However, whether th
Externí odkaz:
https://doaj.org/article/271e11ea0e994e8b91575d007f508fb9
Autor:
Stephen C. Kolwicz Jr.
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Research has demonstrated that the high capacity requirements of the heart are satisfied by a preference for oxidation of fatty acids. However, it is well known that a stressed heart, as in pathological hypertrophy, deviates from its inherent profile
Externí odkaz:
https://doaj.org/article/8c10da1d279942b7822cfab05bf1e2e0
Publikováno v:
Journal of Sport and Health Science, Vol 11, Iss 4, Pp 418-420 (2022)
Externí odkaz:
https://doaj.org/article/e3a2e809e00147eeb20a90cf3d54d127
Autor:
Stephen C. Kolwicz, Jr., PhD, John K. Hall, PhD, Farid Moussavi-Harami, MD, Xiolan Chen, PhD, Stephen D. Hauschka, PhD, Jeffrey S. Chamberlain, PhD, Michael Regnier, PhD, Guy L. Odom, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 7, Pp 778-791 (2019)
Summary: Mutations in the gene encoding for dystrophin leads to structural and functional deterioration of cardiomyocytes and is a hallmark of cardiomyopathy in Duchenne muscular dystrophy (DMD) patients. Administration of recombinant adeno-associate
Externí odkaz:
https://doaj.org/article/4212bb9493db490e828183607656df25