Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Stephen C. Chapin"'
Autor:
Wendy Broom, Thao Duong, Elaine Donohue, Pramod Pandey, Jungwook Kim, Patrick S. Doyle, W. Adam Hill, Nakwon Choi, Stephen C. Chapin
Publikováno v:
Analytical Chemistry. 84:9370-9378
Transcriptional profiling, which is directly or indirectly associated with expressed protein levels, has been used in various applications including clinical prognosis and pharmaceutical investigation of drug activities. Although the widely used reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f884cfd0cfa2d2725c11bf5c4a9948
https://doi.org/10.1021/ac302128u
https://doi.org/10.1021/ac302128u
Publikováno v:
Microfluidics and Nanofluidics. 13:665-674
We report new methods for the synthesis and efficient manipulation of magnetic hydrogel microparticles. Through the development of a high-pH rinsing scheme, we achieve a simple and flexible synthesis strategy for the generation of geometrically and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448d6898798c53745ce135daa051a50a
https://doi.org/10.1007/s10404-012-0977-8
https://doi.org/10.1007/s10404-012-0977-8
Autor:
Daniel C. Pregibon, Tamara Floyd-Smith, Stephen C. Chapin, Ki Wan Bong, David Baah, Patrick S. Doyle
Publikováno v:
Lab Chip. 11:743-747
We present the construction and operation of a compressed-air driven flow system that can be used for a variety of microfluidic applications that require rapid dynamic response and precise control of multiple inlet streams. With the use of inexpensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6fcfb1ecb870ccb98a9462a8a21573
https://doi.org/10.1039/c0lc00303d
https://doi.org/10.1039/c0lc00303d
Publikováno v:
Langmuir. 26:8008-8014
Magnetic polymer particles have been used in a wide variety of applications ranging from targeting and separation to diagnostics and imaging. Current synthesis methods have limited these particles to spherical or deformations of spherical morphologie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1f3d163e22cf84b055e3a443c5e809
https://doi.org/10.1021/la904903g
https://doi.org/10.1021/la904903g
Autor:
Stephen C. Chapin, Ki Wan Bong, Patrick S. Doyle, Michael S. Strano, Karen K. Gleason, Jong-Ho Kim, Jingjing Xu
Publikováno v:
Nature Communications. 3
Flow lithography has become a powerful particle synthesis technique. Currently, flow lithography relies on the use of polydimethylsiloxane microchannels, because the process requires local inhibition of polymerization, near channel interfaces, via ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa6b37b8c2ea1526be6cadf9e25e60b
https://doi.org/10.1038/ncomms1800
https://doi.org/10.1038/ncomms1800
Publikováno v:
Analytical chemistry. 83(23)
Highly sensitive and multiplexed detection of clinically relevant proteins in biologically complex samples is crucial for the advancement of clinical proteomics. In recent years, aptamers have emerged as useful tools for protein analysis due to their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564075d75e3ad58b399eaa97b385eab0
https://pubmed.ncbi.nlm.nih.gov/22017663
https://pubmed.ncbi.nlm.nih.gov/22017663
Publikováno v:
Nature protocols. 6(11)
This protocol describes the core methodology for the fabrication of bar-coded hydrogel microparticles, the capture and labeling of protein targets and the rapid microfluidic scanning of particles for multiplexed detection. Multifunctional hydrogel pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a404f65c3748583c015db9b10954787c
https://pubmed.ncbi.nlm.nih.gov/22015846
https://pubmed.ncbi.nlm.nih.gov/22015846
Autor:
Patrick S. Doyle, Stephen C. Chapin
Publikováno v:
Analytical chemistry. 83(18)
There is great demand for flexible biomolecule analysis platforms that can precisely quantify very low levels of multiple targets directly in complex biological samples. Herein we demonstrate multiplexed quantification of microRNAs (miRNAs) on encode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf685df13469f27730e5e4708bbee5d
https://pubmed.ncbi.nlm.nih.gov/21812442
https://pubmed.ncbi.nlm.nih.gov/21812442
Publikováno v:
PMC
In recent years, there has been a surge in methods to synthesize geometrically and chemically complex microparticles. Analogous to atoms, the concept of a “periodic table” of particles has emerged and continues to be expanded upon. Complementing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63189aee46d826afb6d32d38c611ce16
https://pubmed.ncbi.nlm.nih.gov/21516212
https://pubmed.ncbi.nlm.nih.gov/21516212
Publikováno v:
Analytical chemistry. 83(1)
We demonstrate the use of graphically encoded hydrogel microparticles for the sensitive and high-throughput multiplexed detection of clinically relevant protein panels in complex media. Combining established antibody capture techniques with advances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef68f396cc31fd3dd37eeed58a78120
https://pubmed.ncbi.nlm.nih.gov/21142122
https://pubmed.ncbi.nlm.nih.gov/21142122