Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stephen C. Case-Green"'
Effects of dangling ends on duplex yield have been assessed by hybridisation of oligonucleotides to an array of oligonucleotides synthesised on the surface of a solid support. The array consists of decanucleotides and shorter sequences. One of the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc76b48e868d09553e4c10114cd61498
https://ora.ox.ac.uk/objects/uuid:2ddc02ac-3c82-4fe9-b6ff-a1a3c77e5624
https://ora.ox.ac.uk/objects/uuid:2ddc02ac-3c82-4fe9-b6ff-a1a3c77e5624
Autor:
Paul M. Roberts, James E. Thomson, Stephen C. Case-Green, Angela J. Russell, Stephen G. Davies
The highly diastereoselective aldol reaction between acyl complexes of the iron chiral auxiliary [(η 5-C 5H 5)Fe(CO)(PPh 3)] and β-hydroxy aldehydes (obtained via a Noyori asymmetric hydrogenation), followed by a tandem oxidative decomplexation-cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d67acf44788307e5b2e2fd4298a735
https://ora.ox.ac.uk/objects/uuid:861aae61-26b2-41f1-8833-d8adfeb2782b
https://ora.ox.ac.uk/objects/uuid:861aae61-26b2-41f1-8833-d8adfeb2782b
Publikováno v:
Nucleic Acids Research. 25:1155-1161
We have investigated the use of spacer molecules to reduce steric interference of the support on the hybridisation behaviour of immobilised oligonucleotides. These spacers are built up from a variety of monomeric units, using phosphoramidite chemistr
Publikováno v:
Current opinion in chemical biology. 2(3)
The large amount of DNA sequence information produced in recent years has created a need for high-throughput methods in biology and genetics. These include sequencing, comparing gene sequences and genotyping. DNA arrays promise a highly parallel mean
Autor:
James F. Costello, Stephen G. Davies, Stephen C. Case-Green, Vanessa M. Humphreys, Jeremy C. Primes, Charles J. R. Hedgecock, Michael R. Metzler, Nicholas Heaton
Publikováno v:
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1. (8)
The chiral iron acetyl complexes [Fe(CO)(η5-C 5H5)(L)COCH3] [L = PPh3, P(p-tolyl)3] have been kinetically resolved via aldol reactions involving their derived lithium enolates and camphor in the presence of lithium chloride. With (1R)-(+)-camphor th
Autor:
John Kenneth Elder, Jennifer C. Williams, Stephen C. Case-Green, Matthew P. Johnson, L Wang, Kalim U. Mir, Edwin M. Southern
Publikováno v:
Nucleic acids research. 22(8)
Arrays of oligonucleotides corresponding to a full set of complements of a known sequence can be made in a single series of base couplings in which each base in the complement is added in turn. Coupling is carried out on the surface of a solid suppor
Autor:
Stephen G. Davies, James F. Costello, Jeremy C. Prime, Charles J. R. Hedgecock, Nicholas Heaton, Stephen C. Case-Green
Publikováno v:
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS. (21)
The chiral discrimination displayed between the enolate derived from (RS)-[Fe(η5-C5H5)(CO)(PPh3)COMe] and (1R)-(+)-camphor furnishes a practical route to homochiral (R)-[Fe(η5-C5H5)(CO)(PPh3)COMe] via a kinetic resolution protocol, while a retro-al