Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Stephen C. Billups"'
Autor:
Audrey E Hendricks, Stephen C Billups, Hamish N C Pike, I Sadaf Farooqi, Eleftheria Zeggini, Stephanie A Santorico, Inês Barroso, Josée Dupuis
Publikováno v:
PLoS Genetics, Vol 14, Iss 10, p e1007591 (2018)
A primary goal of the recent investment in sequencing is to detect novel genetic associations in health and disease improving the development of treatments and playing a critical role in precision medicine. While this investment has resulted in an en
Externí odkaz:
https://doaj.org/article/04bb9de3319f4d46ab425323f1bc9b66
Autor:
Peter Graf, Stephen C. Billups
Publikováno v:
Computational Optimization and Applications. 68:671-687
Computational materials design has suffered from a lack of algorithms formulated in terms of experimentally accessible variables. Here we formulate the problem of (ternary) alloy optimization at the level of choice of atoms and their composition that
Autor:
Jeffrey Larson, Stephen C. Billups
Publikováno v:
Computational Optimization and Applications. 64:619-645
This paper presents a trust region algorithm to minimize a function f when one has access only to noise-corrupted function values $$\bar{f}$$f¯. The model-based algorithm dynamically adjusts its step length, taking larger steps when the model and fu
Publikováno v:
SIAM Journal on Optimization. 23:27-53
We propose a derivative-free algorithm for optimizing computationally expensive functions with computational error. The algorithm is based on the trust region regression method by Conn, Scheinberg, and Vicente [A. R. Conn, K. Scheinberg, and L. N. Vi
Autor:
Eleftheria Zeggini, Josée Dupuis, Stephanie A. Santorico, Stephen C. Billups, Inês Barroso, Hamish N C Pike, Audrey E. Hendricks, I. Sadaf Farooqi
Publikováno v:
PLoS Genetics, Vol 14, Iss 10, p e1007591 (2018)
PLoS Genetics
PLoS Genetics
A primary goal of the recent investment in sequencing is to detect novel genetic associations in health and disease improving the development of treatments and playing a critical role in precision medicine. While this investment has resulted in an en
Publikováno v:
Economica. 72:655-681
This paper presents a dynamic model of criminal activity. Individuals are endowed with legal and criminal human capital. Potential incomes in legal and criminal sectors depend on the level of the relevant human capital, the rate of return and random
Autor:
Eman Al-Shemas, Stephen C. Billups
Publikováno v:
Journal of Computational and Applied Mathematics. 170(2):423-432
This paper presents an iterative method for solving the generalized nonlinear set-valued mixed quasi-variational inequality, a problem class that was introduced by Huang et al. (Comp. Math. Appl. 40 (2–3) (2000) 205–215). The method incorporates
Autor:
Janine M. Kennedy, Stephen C. Billups
Publikováno v:
Annals of Operations Research. 119:229-245
Computer-generated plans for radiation treatment sometimes involve an unnecessarily large number of gantry angles. Such plans are time consuming and expensive to administer because each distinct angle causes a delay while the gantry is repositioned.
Autor:
Stephen C. Billups
Publikováno v:
SIAM Journal on Optimization. 12:583-605
This paper develops an algorithm for solving mixed complementarity problems that is based upon probability-one homotopy methods. After the complementarity problem is reformulated as a system of nonsmooth equations, a homotopy method is used to solve
Autor:
Stephen C. Billups, Layne T. Watson
Publikováno v:
SIAM Journal on Optimization. 12:606-626
Convergence theory for a new probability-one homotopy algorithm for solving non-smooth equations is given. This algorithm is able to solve problems involving highly nonlinear equations, where the norm of the residual has nonglobal local minima. The a