Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Stephen C Jameson"'
Autor:
Emily N Truckenbrod, Kristina S Burrack, Todd P Knutson, Henrique Borges da Silva, Katharine E Block, Stephen D O'Flanagan, Katie R Stagliano, Arthur A Hurwitz, Ross B Fulton, Kristin R Renkema, Stephen C Jameson
Publikováno v:
eLife, Vol 10 (2021)
Self-specific CD8+T cells can escape clonal deletion, but the properties and capabilities of such cells in a physiological setting are unclear. We characterized polyclonal CD8+ T cells specific for the melanocyte antigen tyrosinase-related protein 2
Externí odkaz:
https://doaj.org/article/ff7be6cef5c744868a9f63397d655dc6
Autor:
Trupti Vardam-Kaur, Alma Banuelos, Maria Gabaldon-Parish, Bruna Gois Macedo, Caio Loureiro Salgado, Kelsey Marie Wanhainen, Maggie Hanqi Zhou, Sarah van Dijk, Igor Santiago-Carvalho, Angad S. Beniwal, Chloe L. Leff, Changwei Peng, Nhan L. Tran, Stephen C. Jameson, Henrique Borges da Silva
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110290- (2024)
Summary: Sensing of extracellular ATP (eATP) controls CD8+ T cell function. Their accumulation can occur through export by specialized molecules, such as the release channel Pannexin 1 (Panx1). Whether Panx1 controls CD8+ T cell immune responses in v
Externí odkaz:
https://doaj.org/article/bd022071210a4cfc9b97ed22f0917cb0
Autor:
Lisa D S Johnson, Stephen C Jameson
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42268 (2012)
The pleiotropic cytokine TGF-β has been implicated in the regulation of numerous aspects of the immune response, including naïve T cell homeostasis. Previous studies found that impairing TGF-β responsiveness (through expression of a dominant-negat
Externí odkaz:
https://doaj.org/article/9f6fd2ce1a5e4cf481c51793805a178e
Autor:
Tzu-Yu Shao, Tony T. Jiang, Joseph Stevens, Abigail E. Russi, Ty D. Troutman, Anas Bernieh, Giang Pham, John J. Erickson, Emily M. Eshleman, Theresa Alenghat, Stephen C. Jameson, Kristin A. Hogquist, Casey T. Weaver, David B. Haslam, Hitesh Deshmukh, Sing Sing Way
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113323- (2023)
Summary: Intestinal colonization by antigenically foreign microbes necessitates expanded peripheral immune tolerance. Here we show commensal microbiota prime expansion of CD4 T cells unified by the Kruppel-like factor 2 (KLF2) transcriptional regulat
Externí odkaz:
https://doaj.org/article/44014ddf1b0d48c8b50adc38b432ca17
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Conventional T cell subsets are selected in the thymus by peptide bearing MHC expressed by cortical epithelial cells, in contrast cortical thymocytes express non-peptide bearing MHC molecules including CD1d and MR1 and select iNKT and MAIT cell popul
Externí odkaz:
https://doaj.org/article/81950d9bb43444afbba3babc90ee020b
Autor:
Nicholas N, Jarjour, Kelsey M, Wanhainen, Changwei, Peng, Noah V, Gavil, Nicholas J, Maurice, Henrique, Borges da Silva, Ryan J, Martinez, Talia S, Dalzell, Matthew A, Huggins, David, Masopust, Sara E, Hamilton, Stephen C, Jameson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(43)
Interleukin-15 (IL-15) is often considered a central regulator of memory CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7d5d5865f3d44964aaea765a58b86ab
https://pubmed.ncbi.nlm.nih.gov/36260745
https://pubmed.ncbi.nlm.nih.gov/36260745
Autor:
Stephen C. Jameson, Henrique Borges da Silva, Brandon J. Burbach, Ameeta Kelekar, Tingyuan Yang, Stephen O'Flanagan, Bruna de Gois Macedo, Maggie H. Zhou, Changwei Peng, Kelsey M. Wanhainen
Supplementary Table from P2RX7 Enhances Tumor Control by CD8+ T Cells in Adoptive Cell Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a15e65154193da79abb5e44be598f3a
https://doi.org/10.1158/2326-6066.22544783.v1
https://doi.org/10.1158/2326-6066.22544783.v1
Autor:
Stephen C. Jameson, Henrique Borges da Silva, Brandon J. Burbach, Ameeta Kelekar, Tingyuan Yang, Stephen O'Flanagan, Bruna de Gois Macedo, Maggie H. Zhou, Changwei Peng, Kelsey M. Wanhainen
Expression of the purinergic receptor P2RX7 by CD8+ T cells promotes the generation of memory populations following acute infections. However, data suggest that P2RX7 may limit the efficacy of antitumor responses. Herein, we show that P2RX7 is benefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5b879024930683cdb576cb960cf046
https://doi.org/10.1158/2326-6066.c.6550745
https://doi.org/10.1158/2326-6066.c.6550745
Autor:
Stephen C. Jameson, Henrique Borges da Silva, Brandon J. Burbach, Ameeta Kelekar, Tingyuan Yang, Stephen O'Flanagan, Bruna de Gois Macedo, Maggie H. Zhou, Changwei Peng, Kelsey M. Wanhainen
Supplementary Figure from P2RX7 Enhances Tumor Control by CD8+ T Cells in Adoptive Cell Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68655fb1fc6770a7e3567ff2292654ec
https://doi.org/10.1158/2326-6066.22544786.v1
https://doi.org/10.1158/2326-6066.22544786.v1
Autor:
David A. Largaespada, Stephen C. Jameson, Rebecca S. LaRue, David M. Zellmer, Adam J. Litterman
PDF - 930K, Supplementary Figure 1. Individual modifications to culture medium yield a fraction of CD62L+ cells in extended culture Supplementary Figure 2. Cells cultured in cocktail containing medium have greater viability. Supplementary Figure 3. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc666b5de2c3e67d7fd4d4ccf9b4835
https://doi.org/10.1158/2326-6066.22537124
https://doi.org/10.1158/2326-6066.22537124