Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stephen C Heinsch"'
Autor:
Aunica L Kane, Basem Al-Shayeb, Patrick V Holec, Srijay Rajan, Nicholas E Le Mieux, Stephen C Heinsch, Sona Psarska, Kelly G Aukema, Casim A Sarkar, Edward A Nater, Jeffrey A Gralnick
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147036 (2016)
Mercury is a highly toxic heavy metal and the ability of the neurotoxin methylmercury to biomagnify in the food chain is a serious concern for both public and environmental health globally. Because thousands of tons of mercury are released into the e
Externí odkaz:
https://doaj.org/article/cf12fe5e8ea447f6a72042e51a993049
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Bacteria within the genus Streptomyces remain a major source of new natural product discovery and as soil inoculants in agriculture where they promote plant growth and protect from disease. Recently, Streptomyces spp. have been im
Externí odkaz:
https://doaj.org/article/27c0b67172014ccbb054ea5626ae05ff
Autor:
Maciej Maselko, Stephen C. Heinsch, Jeremy M. Chacón, William R. Harcombe, Michael J. Smanski
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible po
Externí odkaz:
https://doaj.org/article/acabf95d0c834ff197052d558dcbfeae
Autor:
Matthew H Zinselmeier, J. Armando Casas-Mollano, Adam Sychla, Stephen C Heinsch, Daniel F Voytas, Michael J Smanski
Understanding how the expression of genes impacts plant development and physiology is important for rationally engineering crop improvements. Programmable Transcription Activators (PTAs), including CRISPRa activators, have traditionally relied on a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aa7c2e3251a429fb57fd17f83d50c7b
https://doi.org/10.1101/2022.06.10.495638
https://doi.org/10.1101/2022.06.10.495638
Autor:
Noelle M. Olson, Jorden A. Johnson, Kerstin E. Peterson, Stephen C. Heinsch, Andrew P. Marshall, Michael J. Smanski, Erin E. Carlson, William C.K. Pomerantz
Publikováno v:
J Fluor Chem
Current experiments that rely on biosynthetic metabolic protein labeling with (19)F often require fluorinated amino acids, which in the case of 2- and 3-fluorotyrosine can be expensive. However, using these amino acids has provided valuable insight i
Recent reports of CRISPR/Cas9-based suppression gene drives in insects underscore the challenge of overcoming genetic resistance. Here we present results from agent-based simulation modeling of a novel Field-Amplified Male Sterility System (FAMSS) th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db3b130d04b2be342b0e128f5d7764d
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Frontiers in Microbiology
Frontiers in Microbiology
Increasing the final titer of a multi-gene metabolic pathway can be viewed as a multivariate optimization problem. While numerous multivariate optimization algorithms exist, few are specifically designed to accommodate the constraints posed by geneti
Autor:
Stephen C. Heinsch, Michael J. Smanski, Jeremy M. Chacón, Maciej Maselko, William R. Harcombe
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Controlling the exchange of genetic information between sexually reproducing populations has applications in agriculture, eradication of disease vectors, control of invasive species, and the safe study of emerging biotechnology applications. Here we
Autor:
Jeffrey A. Gralnick, Patrick V. Holec, Casim A. Sarkar, Edward A. Nater, Aunica L. Kane, Kelly G. Aukema, Srijay S. Rajan, Sona Psarska, Nicholas E. Le Mieux, Stephen C. Heinsch, Basem Al-Shayeb
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 1, p e0147036 (2016)
PLoS ONE, Vol 11, Iss 1, p e0147036 (2016)
Mercury is a highly toxic heavy metal and the ability of the neurotoxin methylmercury to biomagnify in the food chain is a serious concern for both public and environmental health globally. Because thousands of tons of mercury are released into the e