Zobrazeno 1 - 10
of 372
pro vyhledávání: '"Stephen C Cunnane"'
Autor:
Valérie St-Pierre, Gabriel Richard, Etienne Croteau, Mélanie Fortier, Camille Vandenberghe, André C. Carpentier, Bernard Cuenoud, Stephen C. Cunnane
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
The heart and kidney have a high energy requirement, but relatively little is known about their utilization of ketones as a potential energy source. We assessed the metabolism of the ketone tracer, carbon-11 acetoacetate (11C-AcAc), by the left and r
Externí odkaz:
https://doaj.org/article/f8b52fc572c441c1b29cacc75a4e84fc
Autor:
Christian-Alexandre Castellano, Jean-Patrice Baillargeon, Scott Nugent, Sébastien Tremblay, Mélanie Fortier, Hélène Imbeault, Julie Duval, Stephen C Cunnane
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144116 (2015)
ObjectiveTo investigate whether cerebral metabolic rate of glucose (CMRglu) is altered in normal weight young women with polycystic ovary syndrome (PCOS) who exhibit mild insulin resistance.Materials and methodsSeven women with PCOS were compared to
Externí odkaz:
https://doaj.org/article/d1e651f15b224dfd9c21823a98849a9b
Autor:
John C Umhau, Weiyin Zhou, Shantalaxmi Thada, James Demar, Nahed Hussein, Abesh K Bhattacharjee, Kaizong Ma, Sharon Majchrzak-Hong, Peter Herscovitch, Norman Salem, Abigail Urish, Joseph R Hibbeln, Stephen C Cunnane, Stanley I Rapoport, Jussi Hirvonen
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75333 (2013)
Chronic alcohol dependence has been associated with disturbed behavior, cerebral atrophy and a low plasma concentration of docosahexaenoic acid (DHA, 22∶6n-3), particularly if liver disease is present. In animal models, excessive alcohol consumptio
Externí odkaz:
https://doaj.org/article/349a61ee4a27497faa13b83a20432330
Autor:
François Normand-Lauzière, Frédérique Frisch, Sébastien M Labbé, Patrick Bherer, René Gagnon, Stephen C Cunnane, André C Carpentier
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10956 (2010)
It has been proposed that abnormal postprandial plasma nonesterified fatty acid (NEFA) metabolism may participate in the development of tissue lipotoxicity and type 2 diabetes (T2D). We previously found that non-diabetic offspring of two parents with
Externí odkaz:
https://doaj.org/article/ac7a9a3922b84b06a274292f9f62fb91
Autor:
Bernard Cuenoud, Etienne Croteau, Valérie St-Pierre, Gabriel Richard, Mélanie Fortier, Camille Vandenberghe, André C. Carpentier, Stephen C. Cunnane
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Ketones are alternative energy substrates for the heart and kidney but no studies have investigated their metabolism simultaneously in both organs in humans. The present double tracer positron emission tomography (PET) study evaluated the organ distr
Externí odkaz:
https://doaj.org/article/7f946f45654446788263a0bed1e207bf
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
COVID-19 infection causes cognitive changes in the acute phase, but also after apparent recovery. Over fifty post (long)-COVID symptoms are described, including cognitive dysfunction (“brain fog”) precluding return to pre-COVID level of function,
Externí odkaz:
https://doaj.org/article/d311085d83bd407d8fc4b2fbf4e61fde
Autor:
Maggie Roy, Manon Edde, Mélanie Fortier, Etienne Croteau, Christian-Alexandre Castellano, Valérie St-Pierre, Camille Vandenberghe, François Rheault, Mahsa Dadar, Simon Duchesne, Christian Bocti, Tamas Fulop, Stephen C. Cunnane, Maxime Descoteaux
Publikováno v:
Neurobiology of Aging. 115:77-87
Ketones, the brain's alternative fuel to glucose, bypass the brain glucose deficit and improve cognition in mild cognitive impairment (MCI). Our goal was to assess the impact of a 6-month ketogenic intervention on the functional connectivity within e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88252d1d8539980b7d9e487c68571d3e
https://doi.org/10.1016/j.neurobiolaging.2022.04.005
https://doi.org/10.1016/j.neurobiolaging.2022.04.005
Publikováno v:
British Journal of Nutrition. 128:407-423
Alzheimer’s disease (AD) is the most common major neurocognitive disorder of ageing. Although largely ignored until about a decade ago, accumulating evidence suggests that deteriorating brain energy metabolism plays a key role in the development an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48eaecd643a46a2638b8251487326bf0
https://doi.org/10.1017/s0007114521003883
https://doi.org/10.1017/s0007114521003883
Autor:
Juno, Van Valkenburgh, Marlon Vincent V, Duro, Erica, Burnham, Quan, Chen, Shaowei, Wang, Jenny, Tran, Bilal E, Kerman, Sung Hee, Hwang, Xiaodan, Liu, Naomi S, Sta Maria, Francesca, Zanderigo, Etienne, Croteau, Stanley I, Rapoport, Stephen C, Cunnane, Russell E, Jacobs, Hussein N, Yassine, Kai, Chen
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 186
Dysreglulated brain arachidonic acid (AA) metabolism is involved in chronic inflammation and is influenced by apolipoprotein E4 (APOE4) genotype, the strongest genetic risk factor of late-onset Alzheimer's disease (AD). Visualization of AA uptake and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7caae59332bd2e29949d9c98f82cba20
https://pubmed.ncbi.nlm.nih.gov/36341886
https://pubmed.ncbi.nlm.nih.gov/36341886
Autor:
Caroline S Duchaine, Alexandra J Fiocco, Pierre-Hugues Carmichael, Stephen C Cunnane, Mélanie Plourde, Aurélie Lampuré, Benjamin Allès, Sylvie Belleville, Pierrette Gaudreau, Nancy Presse, Guylaine Ferland, Danielle Laurin
Publikováno v:
J Nutr
BACKGROUND: Omega-3 (n–3) PUFAs are suggested to play a role in the prevention of cognitive decline. The evidence may be inconsistent due to methodologic issues, including interrelations with other long-chain (14 or more carbons) fatty acids (LCFAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c32af8fd928fc94a508931fa95da9a5
https://europepmc.org/articles/PMC9445853/
https://europepmc.org/articles/PMC9445853/
