Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Stephen Burge"'
Autor:
Stephen Burge
I.B. Tauris in association with the Institute of Ismaili StudiesProphets serve as intermediaries between the human and divine worlds, granting them a special status in history across diverse religions and cultures. For Muslims, the Prophet Muhammad (
Autor:
Dipender Gill, Marie-Joe Dib, Héléne T. Cronjé, Ville Karhunen, Benjamin Woolf, Eloi Gagnon, Iyas Daghlas, Michael Nyberg, Donald Drakeman, Stephen Burgess
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Drug target Mendelian randomization describes the use of genetic variants as instrumental variables for studying the effects of pharmacological agents. The paradigm can be used to inform on all aspects of drug development and has
Externí odkaz:
https://doaj.org/article/7b25030b6f094cc48073ca0e8a6b8685
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-9 (2024)
Abstract Background Genome-wide association studies have enabled Mendelian randomization analyses to be performed at an industrial scale. Two-sample summary data Mendelian randomization analyses can be performed using publicly available data by anyon
Externí odkaz:
https://doaj.org/article/983a6c7b1a5a41d1b8fb838855775288
Autor:
Stephen Burge
Publikováno v:
Journal of Qur'anic Studies. 24:116-121
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Vitamin D deficiency has been linked to various chronic pain conditions. However, randomized trials of vitamin D supplementation have had mixed results. In contrast, systematic reviews of randomized trials indicate a protective effect of vit
Externí odkaz:
https://doaj.org/article/6ea2bc7ee646435db280bcb6a33341ac
Publikováno v:
PLoS Genetics, Vol 20, Iss 9, p e1011391 (2024)
Mendelian Randomization (MR) is a widely embraced approach to assess causality in epidemiological studies. Two-stage least squares (2SLS) method is a predominant technique in MR analysis. However, it can lead to biased estimates when instrumental var
Externí odkaz:
https://doaj.org/article/00a8fc1d86704dad912b7f796a488051
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Externí odkaz:
https://doaj.org/article/1751332dd7d540d7bde9ef5a0a3cfcf1
Autor:
Oladapo Babajide, Alisa D. Kjaergaard, Weichen Deng, Aleksander Kuś, Rosalie B. T. M. Sterenborg, Bjørn Olav Åsvold, Stephen Burgess, Alexander Teumer, Marco Medici, German Borderline Genomics Consortium, Christina Ellervik, Bass Nick, Panos Deloukas, Eirini Marouli
Publikováno v:
Borderline Personality Disorder and Emotion Dysregulation, Vol 11, Iss 1, Pp 1-7 (2024)
Abstract Background Genome-wide association studies have reported a genetic overlap between borderline personality disorder (BPD) and schizophrenia (SCZ). Epidemiologically, the direction and causality of the association between thyroid function and
Externí odkaz:
https://doaj.org/article/9d21772293b646098d930aeebce06d94
Autor:
Loukas Zagkos, Héléne T. Cronjé, Benjamin Woolf, Roxane de La Harpe, Stephen Burgess, Christos S. Mantzoros, Paul Elliott, Shuai Yuan, Susanna C. Larsson, Ioanna Tzoulaki, Dipender Gill
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Caffeine is one of the most utilized drugs in the world, yet its clinical effects are not fully understood. Circulating caffeine levels are influenced by the interplay between consumption behaviour and metabolism. This study aimed
Externí odkaz:
https://doaj.org/article/263b49f2ef8b4d119a0652d6d922853e
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Mendelian randomization is a popular method for causal inference with observational data that uses genetic variants as instrumental variables. Similarly to a randomized trial, a standard Mendelian randomization analysis estimates
Externí odkaz:
https://doaj.org/article/c9f473150dd5491baf5954549df3ff7b