Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Stephen B. Milne"'
Autor:
D.Lee Gorden, David S. Myers, Pavlina T. Ivanova, Eoin Fahy, Mano R. Maurya, Shakti Gupta, Jun Min, Nathanael J. Spann, Jeffrey G. McDonald, Samuel L. Kelly, Jingjing Duan, M.Cameron Sullards, Thomas J. Leiker, Robert M. Barkley, Oswald Quehenberger, Aaron M. Armando, Stephen B. Milne, Thomas P. Mathews, Michelle D. Armstrong, Chijun Li, Willie V. Melvin, Ronald H. Clements, M.Kay Washington, Alisha M. Mendonsa, Joseph L. Witztum, Ziqiang Guan, Christopher K. Glass, Robert C. Murphy, Edward A. Dennis, Alfred H. Merrill, Jr., David W. Russell, Shankar Subramaniam, H.Alex Brown
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 3, Pp 722-736 (2015)
The spectrum of nonalcoholic fatty liver disease (NAFLD) includes steatosis, nonalcoholic steatohepatitis (NASH), and cirrhosis. Recognition and timely diagnosis of these different stages, particularly NASH, is important for both potential reversibil
Externí odkaz:
https://doaj.org/article/5355a334d12e40fda22b2a610c1de49b
Autor:
Gwynneth Thomas, Jenna L. Betters, Caleb C. Lord, Amanda L. Brown, Stephanie Marshall, Daniel Ferguson, Janet Sawyer, Matthew A. Davis, John T. Melchior, Lawrence C. Blume, Allyn C. Howlett, Pavlina T. Ivanova, Stephen B. Milne, David S. Myers, Irina Mrak, Vera Leber, Christoph Heier, Ulrike Taschler, Jacqueline L. Blankman, Benjamin F. Cravatt, Richard G. Lee, Rosanne M. Crooke, Mark J. Graham, Robert Zimmermann, H. Alex Brown, J. Mark Brown
Publikováno v:
Cell Reports, Vol 5, Iss 2, Pp 508-520 (2013)
The serine hydrolase α/β hydrolase domain 6 (ABHD6) has recently been implicated as a key lipase for the endocannabinoid 2-arachidonylglycerol (2-AG) in the brain. However, the biochemical and physiological function for ABHD6 outside of the central
Externí odkaz:
https://doaj.org/article/458ed2401c5a458c8f277853db671abf
Autor:
Keri A. Tallman, Michelle D. Armstrong, Stephen B. Milne, Lawrence J. Marnett, H. Alex Brown, Ned A. Porter
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 3, Pp 859-868 (2013)
Monitoring lipid distribution and metabolism in cells and biological fluids poses many challenges because of the many molecular species and metabolic pathways that exist. This study describes the synthesis and study of molecules that contain an alkyn
Externí odkaz:
https://doaj.org/article/550ad9f7e7b045629b537255a4a13e76
Autor:
Oswald Quehenberger, Aaron M. Armando, Alex H. Brown, Stephen B. Milne, David S. Myers, Alfred H. Merrill, Sibali Bandyopadhyay, Kristin N. Jones, Samuel Kelly, Rebecca L. Shaner, Cameron M. Sullards, Elaine Wang, Robert C. Murphy, Robert M. Barkley, Thomas J. Leiker, Christian R.H. Raetz, Ziqiang Guan, Gregory M. Laird, David A. Six, David W. Russell, Jeffrey G. McDonald, Shankar Subramaniam, Eoin Fahy, Edward A. Dennis
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 11, Pp 3299-3305 (2010)
The focus of the present study was to define the human plasma lipidome and to establish novel analytical methodologies to quantify the large spectrum of plasma lipids. Partial lipid analysis is now a regular part of every patient's blood test and phy
Externí odkaz:
https://doaj.org/article/18456a2f1f6040868933a01812433287
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 6, Pp 1581-1590 (2010)
A large scale profiling and analysis of glycerophospholipid species in macrophages has facilitated the identification of several rare and atypical glycerophospholipid species. By using liquid chromatography tandem mass spectrometry and comparison of
Externí odkaz:
https://doaj.org/article/0d771880d0cc4010bf4e7a58171a156e
Autor:
Kristin E. Burnum, Dale S. Cornett, Satu M. Puolitaival, Stephen B. Milne, David S. Myers, Susanne Tranguch, H. Alex Brown, Sudhansu K. Dey, Richard M. Caprioli
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 11, Pp 2290-2298 (2009)
Molecular events involved in successful embryo implantation are not well understood. In this study, we used MALDI imaging mass spectrometry (IMS) technologies to characterize the spatial and temporal distribution of phospholipid species associated wi
Externí odkaz:
https://doaj.org/article/a9c1f45fd61d47fb9a3f85c330912923
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 8, Pp 1796-1802 (2005)
The development of a new mass spectrometric lipid profiling methodology permits the identification of cellular phosphatidylinositol monophosphate/phosphatidylinositol bisphosphate/phosphatidylinositol trisphosphate (PIP/PIP2/PIP3) species that includ
Externí odkaz:
https://doaj.org/article/a042de950d594754a6bee1c90c9f9109
Publikováno v:
ACS Chemical Neuroscience. 8:1641-1644
There are multiple treatment options for depression, anxiety, psychosis, and other psychiatric disorders, and psychiatry patients are often comorbid with complex, polypharmacy treatment regimens. Unlike cardiovascular disease and diabetes, there are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e46a5b9165f9df7387236159204b135
https://doi.org/10.1021/acschemneuro.7b00209
https://doi.org/10.1021/acschemneuro.7b00209
Autor:
John Scott Daniels, Candace D. McNaughton, Stephen B. Milne, Ryan D. Morrison, Jeffrey J. Sutherland
Publikováno v:
Hypertension. 72
Employing a novel and proprietary comprehensive precision medicine clinical tool that is a LC/MS/MS-based platform (PrecisCMQ™), we analyzed the serum of HTN patients seeking emergency care (n=293) for the presence and quantity of 42 antihypertensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::017ee6562b6dc41437eb139e5e7cd8d6
https://doi.org/10.1161/hyp.72.suppl_1.p367
https://doi.org/10.1161/hyp.72.suppl_1.p367
Autor:
Thomas M. Daly, Timothy P. Ryan, Elias A. Khawam, Karen Jacobs, J. Scott Daniels, Leo Pozuelo, Ryan D. Morrison, Stephen B. Milne, Jeffrey J. Sutherland
Publikováno v:
ACS chemical neuroscience. 9(3)
Medication exposure is dependent upon many factors, the single most important being if the patient took the prescribed medication as indicated. To assess medication exposure for psychotropic and other medication classes, we enrolled 115 highly adhere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21c6927eada72e059cf8fcd3015758d
https://pubmed.ncbi.nlm.nih.gov/29155555
https://pubmed.ncbi.nlm.nih.gov/29155555