Zobrazeno 1 - 10
of 344
pro vyhledávání: '"Stephen B. McMahon"'
Autor:
Beatrice Oehler, Cindy Périer, Vincent Martin, Amy Fisher, Stéphane Lezmi, Mikhail Kalinichev, Stephen B. McMahon
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Well-established efficacy of botulinum neurotoxin type A (BoNT/A) in aesthetic dermatology and neuromuscular hyperactivity disorders relies on canonical interruption of acetylcholine neurotransmission at the neuromuscular junction at the site of the
Externí odkaz:
https://doaj.org/article/f1a3a232eb484ea6a8f97ed2adf83874
Autor:
Jade B. Jackson, Owen O'Daly, Elena Makovac, Sonia Medina, Alfonso de Lara Rubio, Stephen B. McMahon, Steve C.R. Williams, Matthew A. Howard
Publikováno v:
NeuroImage, Vol 221, Iss , Pp 117178- (2020)
Functional neuroimaging techniques have provided great insight in the field of pain. Utilising these techniques, we have characterised pain-induced responses in the brain and improved our understanding of key pain-related phenomena. Despite the utili
Externí odkaz:
https://doaj.org/article/7dd30c865c4947b3a7df1f31053f11f2
Autor:
David Johannes Hohenschurz-Schmidt, Giovanni Calcagnini, Ottavia Dipasquale, Jade B. Jackson, Sonia Medina, Owen O’Daly, Jonathan O’Muircheartaigh, Alfonso de Lara Rubio, Steven C. R. Williams, Stephen B. McMahon, Elena Makovac, Matthew A. Howard
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
There are bi-directional interactions between the autonomic nervous system (ANS) and pain. This is likely underpinned by a substantial overlap between brain areas of the central autonomic network and areas involved in pain processing and modulation.
Externí odkaz:
https://doaj.org/article/ae58bf13f8b442c585331f77d9127ef3
Publikováno v:
Neurobiology of Disease, Vol 97, Iss , Pp 127-138 (2017)
Chronic pain affects more than 20% of the UK population. Neurotrophic factors have been identified as therapeutic targets to improve current treatments of chronic pain. This review article focuses on nerve growth factor (NGF) and interleukin-6 (IL-6)
Externí odkaz:
https://doaj.org/article/25d8448acfa048e4821524852182c72d
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1771-1781 (2016)
Chronic pain is a common and devastating condition that induces well-characterized changes in neurons and microglia. One major unanswered question is why these changes should persist long after the precipitating injury has healed. Here, we suggest th
Externí odkaz:
https://doaj.org/article/7d8bc14062e94249bfbb8c6ddcacaf20
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
The dorsal root ganglia (DRG) and trigeminal ganglia (TG) are clusters of cell bodies of highly specialized sensory neurons which are responsible for relaying information about our environment to the central nervous system. Despite previous efforts t
Externí odkaz:
https://doaj.org/article/2b891e549cd844c09e8d7f505c2a0ee8
Autor:
Nicholas D. James, Maria Angéria, Elizabeth J. Bradbury, Peter Damberg, Stephen B. McMahon, Mårten Risling, Thomas Carlstedt
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
In a recent clinical report, return of the tendon stretch reflex was demonstrated after spinal cord surgery in a case of total traumatic brachial plexus avulsion injury. Peripheral nerve grafts had been implanted into the spinal cord to reconnect to
Externí odkaz:
https://doaj.org/article/65a059fe662e465d9cb2cf73e8ff20dc
Publikováno v:
Cell Transplantation, Vol 26 (2017)
The central branches of the C7 and C8 dorsal roots were avulsed close to their entry point into the spinal cord in adult rats. The forepaw responses to heat and cold stimuli were tested at 1, 2, and 3 weeks after injury. Over this period, the paws we
Externí odkaz:
https://doaj.org/article/e60e3c52e98a4e618a237c5f3ebb1651
Autor:
Eleni Sinopoulou, Aline Barroso Spejo, Naomi Roopnarine, Emily R. Burnside, Katalin Bartus, Fred De Winter, Stephen B. McMahon, Elizabeth J. Bradbury
Publikováno v:
Journal of Neuroscience Research, 100, 2055-2076. Wiley-Liss Inc.
Cervical level spinal cord injury (SCI) can severely impact upper limb muscle function, which is typically assessed in the clinic using electromyography (EMG). Here, we established novel preclinical methodology for EMG assessments of muscle function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e877cb9846a5f6dee2a799a39887031a
https://doi.org/10.1002/jnr.25111
https://doi.org/10.1002/jnr.25111
Autor:
Olivia S. Kowalczyk, Sonia Medina, Dimitra Tsivaka, Stephen B. McMahon, Steven C. R. Williams, Jonathan C. W. Brooks, David J. Lythgoe, Matthew A. Howard
Resting fMRI studies have identified intrinsic spinal cord activity, which forms organised motor (ventral) and sensory (dorsal) resting-state networks. However, to facilitate the use of spinal fMRI in, for example, clinical studies, it is crucial to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88b5e22002165b2110202abffab680b8
https://doi.org/10.1101/2023.02.27.530185
https://doi.org/10.1101/2023.02.27.530185
