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pro vyhledávání: '"Stephen B. Hunter"'
Supplementary Methods from Overexpression of MBD2 in Glioblastoma Maintains Epigenetic Silencing and Inhibits the Antiangiogenic Function of the Tumor Suppressor Gene BAI1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238e3e3cb456df33a85e5d094d0037dd
https://doi.org/10.1158/0008-5472.22389405.v1
https://doi.org/10.1158/0008-5472.22389405.v1
Autor:
Silvio Notari, Francisco J Moleres, Stephen B Hunter, Ermias D Belay, Lawrence B Schonberger, Ignazio Cali, Piero Parchi, Wun-Ju Shieh, Paul Brown, Sherif Zaki, Wen-Quan Zou, Pierluigi Gambetti
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8765 (2010)
BackgroundVariant Creutzfeldt-Jakob disease (vCJD) is a prion disease thought to be acquired by the consumption of prion-contaminated beef products. To date, over 200 cases have been identified around the world, but mainly in the United Kingdom. Thre
Externí odkaz:
https://doaj.org/article/28fe48923f9445478b550bf34da11624
Autor:
Dianne Alexis, Daniel J. Brat, Candace Chisolm, Jeffrey J. Olson, Cristina Vincentelli, Costas G. Hadjipanayis, Stephen B. Hunter, Chunhai Hao, Matthew Schniederjan, Jingjing Gao, Mike Torian, Christina L. Appin
Publikováno v:
Brain Pathology. 23:454-461
Glioblastoma (GBM) is an aggressive primary brain tumor with an average survival of approximately 1 year. A recently recognized subtype, glioblastoma with oligodendroglioma component (GBM-O), was designated by the World Health Organization (WHO) in 2
Publikováno v:
Cancer Research. 71:5859-5870
Brain angiogenesis inhibitor 1 (BAI1) is a putative G protein–coupled receptor with potent antiangiogenic and antitumorigenic properties that is mutated in certain cancers. BAI1 is expressed in normal human brain, but it is frequently silenced in g
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 19:246-252
The role of Epstein-Barr virus (EBV) in the pathogenesis of multiple sclerosis (MS) is still elusive. In 2007, Serafini et al demonstrated the direct role of EBV in brain lesions of MS patients. They found positive immunohistochemistry (IHC) staining
Publikováno v:
Proceedings of the National Academy of Sciences. 105:7570-7575
Isoform A of phosphatidylinositol 3-kinase enhancer (PIKE-A) is a newly identified prooncogenic factor that has been implicated in cancer cell growth. How PIKE-A activity is regulated in response to growth signal is poorly understood. Here, we demons
Autor:
Chen Yih Ou, John R. Goldblum, Josiah N. Wilcox, David Monson, Andrew N. Young, Sharon W. Weiss, Jack L. Arbiser, John D. L. Nolen, David L. Jaye, Stephen B. Hunter, Vijay Varma
Publikováno v:
Human Pathology. 36:987-993
Apolipoprotein D (apoD) expression was studied in nonneoplastic peripheral nerve, neurofibromas (NFs), and malignant peripheral nerve sheath tumors (MPNSTs) by quantitative polymerase chain reaction, in situ hybridization, and immunohistochemistry. M
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 36:1046-1069
The invasion of neoplastic cells into healthy brain tissue is a pathologic hallmark of gliomas and contributes to the failure of current therapeutic modalities (surgery, radiation and chemotherapy). Transformed glial cells share the common attributes
Autor:
Amilcar A. Castellano-Sanchez, Sarojini N. Devi, Erwin G. Van Meir, Marcia Pecot, Cynthia Cohen, Balveen Kaur, Elizabeth H. Hammond, Daniel J. Brat, Stephen B. Hunter
Publikováno v:
Cancer Research. 64:920-927
Necrosis and vascular proliferation are the pathologic features that distinguish the most malignant infiltrative astrocytoma, glioblastoma (GBM), from those of lower grades. In GBM, hypercellular zones called pseudopalisades typically surround necrot
Publikováno v:
Advances in Anatomic Pathology. 10:212-217
Summary:Glioblastoma multiforme (GBM) is the highest-grade infiltrative astrocytoma and also the most common. It is generally associated with a dismal prognosis (mean survival 11 months), yet individual patient survivals vary. Histologic parameters h