Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stephen B. Boulware"'
Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes
Autor:
Junhua Zhao, Guliang Wang, Imee M. del Mundo, Jennifer A. McKinney, Xiuli Lu, Albino Bacolla, Stephen B. Boulware, Changsheng Zhang, Haihua Zhang, Pengyu Ren, Catherine H. Freudenreich, Karen M. Vasquez
Publikováno v:
Cell Reports, Vol 22, Iss 5, Pp 1200-1210 (2018)
Summary: Sequences with the capacity to adopt alternative DNA structures have been implicated in cancer etiology; however, the mechanisms are unclear. For example, H-DNA-forming sequences within oncogenes have been shown to stimulate genetic instabil
Externí odkaz:
https://doaj.org/article/29090ebd0ad548ea94a5b4dbe1f900e7
Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes
Autor:
Guliang Wang, Albino Bacolla, Changsheng Zhang, Junhua Zhao, Pengyu Ren, Jennifer A. McKinney, Catherine H. Freudenreich, Karen M. Vasquez, Xiuli Lu, Stephen B. Boulware, Haihua Zhang, Imee Marie A. del Mundo
Publikováno v:
Cell Reports, Vol 22, Iss 5, Pp 1200-1210 (2018)
Summary: Sequences with the capacity to adopt alternative DNA structures have been implicated in cancer etiology; however, the mechanisms are unclear. For example, H-DNA-forming sequences within oncogenes have been shown to stimulate genetic instabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4252e710409bd3513a68446894e5d62d
http://www.sciencedirect.com/science/article/pii/S2211124718300317
http://www.sciencedirect.com/science/article/pii/S2211124718300317
Autor:
Laura A. Christensen, Rick A. Finch, Howard D. Thames, Lezlee G Coghlan, Karen M. Vasquez, Stephen B. Boulware
Publikováno v:
Molecular Carcinogenesis. 53:744-752
Antimetabolite chemotherapy remains an essential cancer treatment modality, but often produces only marginal benefit due to the lack of tumor specificity, the development of drug resistance, and the refractoriness of slowly proliferating cells in sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5435754efd64bcd59d2e8f71dd6d1ea9
https://doi.org/10.1002/mc.22026
https://doi.org/10.1002/mc.22026
Autor:
K.L. Powell, Erika L. Abel, Elizabeth McIvor, Stephen B. Boulware, Michael C. MacLeod, Karen M. Vasquez, John DiGiovanni, Tammy Y. Fields
Publikováno v:
Toxicology and Applied Pharmacology. 266:439-442
Mustard gas, used in chemical warfare since 1917, is a mutagenic and carcinogenic agent that produces severe dermal lesions for which there are no effective therapeutics; it is currently seen as a potential terrorist threat to civilian populations. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4dcf4f9d7db86b78b6bafad14d7218
https://doi.org/10.1016/j.taap.2012.11.020
https://doi.org/10.1016/j.taap.2012.11.020
Autor:
Tammy Y. Fields, Elizabeth McIvor, Stephen B. Boulware, Michael C. MacLeod, Erika L. Abel, Karen M. Vasquez, K. Leslie Powell
Publikováno v:
Toxicology and Applied Pharmacology. 263:203-209
Sulfur mustard [bis(2-chloroethyl)sulfide, SM] is a well-known DNA-damaging agent that has been used in chemical warfare since World War I, and is a weapon that could potentially be used in a terrorist attack on a civilian population. Dermal exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68072f15fbf0ac9ac04b4b257894058e
https://doi.org/10.1016/j.taap.2012.06.010
https://doi.org/10.1016/j.taap.2012.06.010
Autor:
Karen M. Vasquez, K. Leslie Powell, Howard D. Thames, Stephen B. Boulware, Michael C. MacLeod
Sulfur mustard (bis-(2-chloroethyl)sulfide) is a well-known chemical warfare agent that induces debilitating cutaneous toxicity in exposed individuals. It is also known to be carcinogenic and mutagenic because of its ability to damage DNA via electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffcdd13a40d80622354d241178b8c58
https://europepmc.org/articles/PMC2838951/
https://europepmc.org/articles/PMC2838951/
